Metallaboratranes: Soft Scorpionates and Masked Metal Bases. All molecular metal compounds involve a metal surrounded by a group of electron donors (?ligands?). The design and manipulation of these ligand sets and their interactions with metals (?coordination chemistry?) underpins ALL applications of metals, be they in biological, pharmaceutical, materials or industrial applications. This proposal addresses the diametric opposite - the role-reversal wherein a metal centre acts as an electron don ....Metallaboratranes: Soft Scorpionates and Masked Metal Bases. All molecular metal compounds involve a metal surrounded by a group of electron donors (?ligands?). The design and manipulation of these ligand sets and their interactions with metals (?coordination chemistry?) underpins ALL applications of metals, be they in biological, pharmaceutical, materials or industrial applications. This proposal addresses the diametric opposite - the role-reversal wherein a metal centre acts as an electron donor to a ligand. This rare situation has only recently been firmly established in this research group, but promises to be part of a wider new coordination chemistry, the limits of which will be pursued in the proposed work.Read moreRead less
A Midas touch for electrophiles in new reaction development. This project aims to address the lack of knowledge about how high-value organic molecules are formed in gold-catalysed reactions by advancing a novel mode of catalysis. This project expects to generate new knowledge about these gold-catalysed reactions using an innovative, interdisciplinary approach incorporating computational and synthetic techniques. Expected outcomes of this project include the optimisation and development of import ....A Midas touch for electrophiles in new reaction development. This project aims to address the lack of knowledge about how high-value organic molecules are formed in gold-catalysed reactions by advancing a novel mode of catalysis. This project expects to generate new knowledge about these gold-catalysed reactions using an innovative, interdisciplinary approach incorporating computational and synthetic techniques. Expected outcomes of this project include the optimisation and development of important organic reactions and enhancing collaboration nationally and internationally between computational and synthetic chemists. This should provide significant benefits in the form of improved chemical reactions for chemists to prepare new pharmaceuticals, agrochemicals and materials.Read moreRead less
Switchable and stereocontrolled photoredox catalysis. This project aims to develop new catalytic synthetic reactions for the rapid and more direct functionalisation of organic compounds under mild conditions with the use of visible light. An integrated experimental and computational approach will be used to design potent visible-light photocatalysts that retain the advantages of standard photoredox catalysis but with the added ability to intercept and, thus control, reactive intermediates in sit ....Switchable and stereocontrolled photoredox catalysis. This project aims to develop new catalytic synthetic reactions for the rapid and more direct functionalisation of organic compounds under mild conditions with the use of visible light. An integrated experimental and computational approach will be used to design potent visible-light photocatalysts that retain the advantages of standard photoredox catalysis but with the added ability to intercept and, thus control, reactive intermediates in situ. This will enable the control of stereochemistry in photoredox reactions – not possible with standard catalysts - and establish other useful synthetic transformations. These strategies will make it easier to prepare valuable classes of organic molecules – efficiently, safely, and cost-effectively.
Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100177
Funder
Australian Research Council
Funding Amount
$300,000.00
Summary
Advanced electron paramagnetic resonance (EPR) facilities for chemical, biological and materials sciences. New instrumentation to advance national research in hydrogen fuel generation from renewable sources, new generation photo-voltaic technologies, novel polymer and other chemical materials and advanced computing systems will be provided by this project. A new high sensitivity electron paramagnetic resonance facility, located at the Australian National University, will serve researchers in the ....Advanced electron paramagnetic resonance (EPR) facilities for chemical, biological and materials sciences. New instrumentation to advance national research in hydrogen fuel generation from renewable sources, new generation photo-voltaic technologies, novel polymer and other chemical materials and advanced computing systems will be provided by this project. A new high sensitivity electron paramagnetic resonance facility, located at the Australian National University, will serve researchers in the ACT region devoted to the broad range of activities summarised above. A particular focus involves novel, biologically inspired energy systems and high efficiency solar cell technology.Read moreRead less
A new route to linear alpha olefins - catalytic isomerisation of internal olefins. Linear alpha olefins are an extremely important class of chemical building blocks used for everyday consumer products, such as plastics, detergents and lubricants. This research aims to develop a new platform technology for the production of these materials from low cost precursors.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0775548
Funder
Australian Research Council
Funding Amount
$180,000.00
Summary
Advanced characterisation facilities for functional nanostructured materials. A critical factor that enhances frontier research is a set of advanced core research experimental facilities for material characterisation purposes. The proposed equipment aims to: (1) provide research facilities for advanced nanomaterial research; (2) improve national competitiveness and growth in a knowledge-based economy; and (3) foster local talented researchers in order to meet the strategic needs of the nation fo ....Advanced characterisation facilities for functional nanostructured materials. A critical factor that enhances frontier research is a set of advanced core research experimental facilities for material characterisation purposes. The proposed equipment aims to: (1) provide research facilities for advanced nanomaterial research; (2) improve national competitiveness and growth in a knowledge-based economy; and (3) foster local talented researchers in order to meet the strategic needs of the nation for a sustainable environment. These activities will revitalise Australia's leading role in creating new technologies with particular relevance to using advanced nanostructures for the production of clean air and water, and sustainable energy alternatives.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100236
Funder
Australian Research Council
Funding Amount
$180,000.00
Summary
Facilities for spectroscopy and diffraction at high pressures. The provision of infrastructure for the study of novel materials under high pressures will enhance Australia's capability in creating new materials and in creating new devices that meet needs in communication, environment and medicine applications. The new facility will enable researchers to understand the response of structures to extreme pressures and will exploit the unique capabilities of the synchrotron light.
The mechanism of water splitting in photosynthesis. Sunlight reaching the earth is used by the vast body of plants and algae living in surface waters and on the land to drive photosynthesis. One of the most fundamental contributions that photosynthesis provides to the Biosphere is the gaseous oxygen produced by its water-splitting chemistry - ~300 gigatons of O2 are released into the atmosphere per year. However, the mechanism behind water-splitting is not precisely known. We will use a range o ....The mechanism of water splitting in photosynthesis. Sunlight reaching the earth is used by the vast body of plants and algae living in surface waters and on the land to drive photosynthesis. One of the most fundamental contributions that photosynthesis provides to the Biosphere is the gaseous oxygen produced by its water-splitting chemistry - ~300 gigatons of O2 are released into the atmosphere per year. However, the mechanism behind water-splitting is not precisely known. We will use a range of unique experimental approaches to determine the molecular mechanism of the photosynthetic water-splitting chemistry. The understanding of this reaction will provide the molecular blueprint for the development of efficient biocatalysts to generate H2 and O2 from water.Read moreRead less
Characterising and exploiting hydrogen tunnelling in environmentally and medically important enzymes. Theory and experiment will be used to study environmentally and medically important enzymes, and quantify the role that hydrogen tunnelling plays in their activity. The project will determine the basis of their remarkable ability to catalyse chemical reactions, and to engineer and design more efficient proteins and pharmaceuticals.