Stuttering in childhood: Patterns of recovery and persistence. This project will benefit the 1 in 20 Australian children who stutter and their families. We will learn for the first time how stuttering impacts on child development in the early school years and document the relationship between stuttering and other childhood conditions. The study will produce much needed information about recovery from stuttering and stuttering persistence. Therefore new knowledge will result to inform the scienti ....Stuttering in childhood: Patterns of recovery and persistence. This project will benefit the 1 in 20 Australian children who stutter and their families. We will learn for the first time how stuttering impacts on child development in the early school years and document the relationship between stuttering and other childhood conditions. The study will produce much needed information about recovery from stuttering and stuttering persistence. Therefore new knowledge will result to inform the scientific community and provide professionals and families with much needed evidence-based information about stuttering progression. Together this information will inform intervention approaches and help direct resources to those children who need them most. Read moreRead less
Attentional mechanisms in the relationship between sleep disruption and academic outcomes in Australian school children. This project will assess the impact of sleep problems on attention and academic performance in primary school children. The project will investigate typically developing children and children with developmental disorders over 18 months. The research will advance knowledge of the interplay between sleep, attention and learning across development.
Promoting healthy eating, active play and sustainability awareness in early childhood curricula: Addressing the Ben10™ problem. A pedagogical communication strategy has been developed to allow early childhood educators to design curriculum interventions that support children’s learning about healthy eating, the importance of active play and the sustainability consequences of their food and toy selections. The aim of this study is to conduct a randomised trial to evaluate the efficacy of the curr ....Promoting healthy eating, active play and sustainability awareness in early childhood curricula: Addressing the Ben10™ problem. A pedagogical communication strategy has been developed to allow early childhood educators to design curriculum interventions that support children’s learning about healthy eating, the importance of active play and the sustainability consequences of their food and toy selections. The aim of this study is to conduct a randomised trial to evaluate the efficacy of the curriculum interventions, developed by teachers using this pedagogical communication strategy, on children’s knowledge about healthy eating, active play and the sustainability consequences of their food and toy selections. This project connects strongly with the learning outcomes of the National Early Years Learning Framework and the Australian Curriculum to be implemented in 2014.Read moreRead less
A study of early stuttering. Stuttering affects 1 in 20 Australian children. Stuttering disrupts and prevents normal verbal communication, significantly interferes with social interaction and can affect the attainment of educational and occupational potential. Australia leads the world in stuttering research. This innovative study will document the onset of stuttering and describe its progression, an area that is not well described or understood. This project will contribute new knowledge about ....A study of early stuttering. Stuttering affects 1 in 20 Australian children. Stuttering disrupts and prevents normal verbal communication, significantly interferes with social interaction and can affect the attainment of educational and occupational potential. Australia leads the world in stuttering research. This innovative study will document the onset of stuttering and describe its progression, an area that is not well described or understood. This project will contribute new knowledge about the onset of stuttering thereby benefiting children worldwide and their families. It will inform clinical practice and improve the evidence underpinning the advice given to parents of children who stutter.Read moreRead less
The cognitive neuroscience of executive control: behavioural, physiological and genetic mechanisms. How genes influence our human abilities to think, reason and control behaviour has puzzled scientists for decades. The human genome project has allowed us to ask how individual genes influence these capacities. Understanding the genetics of these abilities provides a solid platform from which to launch gene discovery projects in clinical disorders where these abilities are compromised. The curr ....The cognitive neuroscience of executive control: behavioural, physiological and genetic mechanisms. How genes influence our human abilities to think, reason and control behaviour has puzzled scientists for decades. The human genome project has allowed us to ask how individual genes influence these capacities. Understanding the genetics of these abilities provides a solid platform from which to launch gene discovery projects in clinical disorders where these abilities are compromised. The current project is directly relevant to the genetics of mental disorders, such as attention deficit hyperactivity (ADHD), that place a large burden, both financially and emotionally, on our society. Understanding the genes and biological pathways that increase risk for mental disorders will ultimately lead to improved treatments for these conditions.Read moreRead less
Detection and Quantification of General Fetal Movements from Accelerometer Measurements using Nonstationary Signal Processing Techniques. There are approximately 1,750 fetal deaths per year in Australian with about one-third occurring late in gestation and without an apparent cause. The development of an automated system capable of long-term monitoring of fetal health will result in accurate diagnoses and prediction of future outcome. This will, in turn, allow early intervention by the clinicia ....Detection and Quantification of General Fetal Movements from Accelerometer Measurements using Nonstationary Signal Processing Techniques. There are approximately 1,750 fetal deaths per year in Australian with about one-third occurring late in gestation and without an apparent cause. The development of an automated system capable of long-term monitoring of fetal health will result in accurate diagnoses and prediction of future outcome. This will, in turn, allow early intervention by the clinician to reduce fetal deaths and enhance the chances of good outcomes with resultant savings in social and financial costs to the community. The development of such equipment would spawn future research into intervention treatments and contribute to Australia's position as a world leader in computerised health monitoring systems.Read moreRead less
Understanding influences on physical activity and sedentary behaviour from preschool to preadolescence. While promotion of optimal levels of physical activity and sedentary behaviours during childhood is important for health, much remains unknown in this field. This study will extend an existing cohort of children, recruited at ages three to five years and followed up at six to eight years by reassessing these children at nine to eleven years. Novel additions to the cohort include long term foll ....Understanding influences on physical activity and sedentary behaviour from preschool to preadolescence. While promotion of optimal levels of physical activity and sedentary behaviours during childhood is important for health, much remains unknown in this field. This study will extend an existing cohort of children, recruited at ages three to five years and followed up at six to eight years by reassessing these children at nine to eleven years. Novel additions to the cohort include long term follow-up spanning preschool to preadolescence, application of an ecological framework, and collection of objective neighbourhood data using a Geographical Information System. Findings will provide important information for policy and interventions focused at the individual, family and neighbourhood level, to improve physical activity and sedentary behaviour levels across childhood.Read moreRead less
Multi-scale modelling of cell migration in developmental biology. Interpretative and predictive tools are needed for the comprehensive understanding of directed cell migration in the medical sciences. Mathematical models and modelling methodologies developed in this project will make a significant contribution to the investigation of cell migration and the testing and generation of hypotheses. Such models are needed to understand observed cellular patterns. This project will contribute to knowle ....Multi-scale modelling of cell migration in developmental biology. Interpretative and predictive tools are needed for the comprehensive understanding of directed cell migration in the medical sciences. Mathematical models and modelling methodologies developed in this project will make a significant contribution to the investigation of cell migration and the testing and generation of hypotheses. Such models are needed to understand observed cellular patterns. This project will contribute to knowledge of normal and abnormal developmental processes, especially in embryonic growth. Understanding these processes should lead to prediction and treatment of congenital disorders and contribute to a healthy start to life.Read moreRead less
Framing and Enabling Children’s Active Play using Novel Technology. This project aims to address inactivity in the 3-5 age group through understanding and exploring innovative interactive active play experiences for children, with a view to increasing their physical activity over the long term. This project will be based on empirical research with real children undertaking real interactive experiences in real contexts, in order to understand issues around sustained engagement with these types of ....Framing and Enabling Children’s Active Play using Novel Technology. This project aims to address inactivity in the 3-5 age group through understanding and exploring innovative interactive active play experiences for children, with a view to increasing their physical activity over the long term. This project will be based on empirical research with real children undertaking real interactive experiences in real contexts, in order to understand issues around sustained engagement with these types of systems. We will design and develop solutions that may address the issues and test those interventions in a longitudinal manner. The outcome will be a framework which can be applied in a variety of situations and modalities by designers and developers of such systems, and feed into childhood technology guidelines.
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An Investigation of Novel Sialylmimetics as Inhibitors of Rotavirus. Rotavirus causes severe gastroenteritis in infants worldwide. Over 125 million cases of diarrhoea and 800,000 deaths annually are attributed to rotavirus. The process that enables this debilitating and sometimes fatal disease to infect cells is poorly understood. This project aims to produce a range of unique chemical entities that will provide information about the way rotavirus infects cells. The chemical compounds produc ....An Investigation of Novel Sialylmimetics as Inhibitors of Rotavirus. Rotavirus causes severe gastroenteritis in infants worldwide. Over 125 million cases of diarrhoea and 800,000 deaths annually are attributed to rotavirus. The process that enables this debilitating and sometimes fatal disease to infect cells is poorly understood. This project aims to produce a range of unique chemical entities that will provide information about the way rotavirus infects cells. The chemical compounds produced in this study will be evaluated for their ability to prevent rotavirus from infecting cells. It is expected that this project will provide compounds that may ultimately be used as drugs for the treatment of rotavirus.Read moreRead less