Characterisation Of Rotavirus Vaccine Escape - Potential For Significant Impact On Vaccination Program
Funder
National Health and Medical Research Council
Funding Amount
$531,689.00
Summary
The introduction of rotavirus vaccines have had enormous impact on improving the health of children worldwide. However, the emergence of vaccine escape strains has the potential to significantly reduce the vaccine effectiveness. This study proposes to characterise strains able to escape vaccine protection.
Respiratory Syncytial Virus Matrix Protein-Host Protein Interactions As Targets For Therapeutics
Funder
National Health and Medical Research Council
Funding Amount
$686,885.00
Summary
Respiratory syncytial virus (RSV) causes more deaths in winter than influenza, being the major cause of viral pneumonia in infants worldwide, and a potent lower respiratory pathogen in the elderly and immunosuppressed adults. The present proposal will apply a range of techniques to search for new inhibitors of viral infection which target host-virus interactions, as the first step towards new generation anti-viral agents to treat RSV infection.