Improving Outcomes For Children With ADHD: Mapping Developmental Trajectories And Developing Targeted Interventions
Funder
National Health and Medical Research Council
Funding Amount
$419,180.00
Summary
Attention deficit hyperactivity disorder (ADHD) is one of the most common mental health disorders affecting young people in Australia. My research program aims to generate new knowledge to inform clinical practice for children with ADHD including: 1) long-term outcomes and key predictors of outcomes; and 2) novel treatments to improve the lives of children and families. Growth of my research program is feasible and underpinned by existing platforms including numerous NHMRC-funded studies.
The Role Of The Zinc Finger Transcriptional Repressor Znf238 During Nerve Cell Maturation
Funder
National Health and Medical Research Council
Funding Amount
$394,264.00
Summary
Proper foetal brain assembly is critical for brain function, but the underlying genetic mechanisms remain poorly defined. In this study, I will investigate a family of proteins that “turn on” neural gene expression in combination with another protein that “turns off” their expression during nerve cell development. Understanding this novel on/off mechanism for controlling gene expression in newborn nerve cells will further our understanding of how the brain is assembled.
Neuroimaging In Mental Health: The Quest For Clinically Useful Biomarkers
Funder
National Health and Medical Research Council
Funding Amount
$437,034.00
Summary
To ultimately improve treatment of mental illness, this research program aims to detect robust and reliable neuroimaging markers that are associated with affective disorders by pooling data from many samples across the world. Moreover, this research aims to develop alternative biological-based classifications of mental illness in young people, and evaluate their clinical value by examining their predictive value for treatment response and disease course.