Human Neural Development In The Absence Of Species-expected Stimuli: The Effect Of Maternal Or Social Deprivation On Maturation Of Emotion Circuitry During Critical Periods Of Development.
Funder
National Health and Medical Research Council
Funding Amount
$465,103.00
Summary
As children mature into adolescents, social influences on emotional responding transition from parents to peers. Understanding how social stimuli shape neural circuits that ultimately regulate emotional behaviour will yield critical information for treatment and prevention of emotional disorders across the lifespan. The current project addresses this important issue through the use of functional imaging of emotion circuits in the brain and classical conditioning approaches to emotion responding.
Behavioural And Neuropsychiatric Aspects Of Transition To Severe Conduct Disorder In Adolescence.
Funder
National Health and Medical Research Council
Funding Amount
$343,100.00
Summary
Conduct disorder represents an enormous cost to Australian society directly via the mental health and forensic systems, and indirect costs via its associations with other mental health problems, relationship problems, impaired social functioning, and substance use problems. Behavioural-family-based treatment have good success rates with young children with cooperative parents, however, there are a minority who progress to chronic problems despite this. Risk and resilience factors identifying chr ....Conduct disorder represents an enormous cost to Australian society directly via the mental health and forensic systems, and indirect costs via its associations with other mental health problems, relationship problems, impaired social functioning, and substance use problems. Behavioural-family-based treatment have good success rates with young children with cooperative parents, however, there are a minority who progress to chronic problems despite this. Risk and resilience factors identifying chronic patterns in early childhood are the key to early intervention. In previous research, this research team showed for the first time that callous-unemotional traits, a feature of chronic psychopathy, could be measured in children as young as 4 years, and was predictive of a range of negative outcomes. However, it was also found that the key neuropsychiatric markers characteristic of psychopathy, including reward dominance-punishment insensitivity and deficits in affective empathy, did not exist in conduct problem children prior to adolescence. Around the time of puberty, it appears that important changes occur in cognitive-affective processing styles that are associated with the adult form of psychopathy and antisocial behaviour. Thus, this research raises critical questions about the development of severe antisocial behaviour (or psychopathy) through the childhood to adolescent years. Our evidence indicates that early adolecence may be the period when intrapsychological characteristics representing chronic risk become concrete. The current research will be the first to map the development common neuropsychiatric markers (affective empathy, punishment insensitivity) of severe antisocial processes through the late childhood-adolescent period. The findings will have clear implications for models of antisocial behaviour and clinical approaches to working with conduct problem children and adolescents.Read moreRead less
Socioeconomic Variation In Community Risk Profiles Associated With Health And Behaviour Problems In Adolescents
Funder
National Health and Medical Research Council
Funding Amount
$459,700.00
Summary
Until recently, emotional and behavioural problems of adolescence have tended to be dismissed as part of the normal turbulence of adolescent development; however, attitudes to adolescent health and health promotion have changed quickly. Downward age-trends in tobacco, alcohol and illicit drug use have made adolescents a major target for health promotion. The practical potential for adolescent mental health promotion has gained considerable ground and knowledge of the modifiable determinants of y ....Until recently, emotional and behavioural problems of adolescence have tended to be dismissed as part of the normal turbulence of adolescent development; however, attitudes to adolescent health and health promotion have changed quickly. Downward age-trends in tobacco, alcohol and illicit drug use have made adolescents a major target for health promotion. The practical potential for adolescent mental health promotion has gained considerable ground and knowledge of the modifiable determinants of youth mental health problems has been progressed by a growing number of studies examining distal and proximal predictors in community samples. The project plans to comprehensively assess locally elevated risk factors and depressed protective factors predictive of a range of adolescent health and behaviour problems including substance abuse, obesity and depression in 30 communities across three Australian States. These communities will be selected from the entire socioeconomic spectrum to determine how the social context of our neighbourhoods may influence the health and behaviour of adolescents . Surveys of students in grade 6 and year 8 will be conducted. Each participating student will be weighed and measured and asked to complete a questionnaire that assesses a comprehensive range of community risk and protective factors.Read moreRead less
The Structure Of Negative Affective States In Youth: Identifying The Core Symptoms Of Depression, Anxiety And Tension/stress In Children And Adolescents
Funder
National Health and Medical Research Council
Funding Amount
$241,016.00
Summary
This project will lead to improved knowledge about the symptoms that define depression and anxiety in children and adolescents. The results will also inform us about the development of tension/stress as a unique emotional state associated with excessive worrying. The publication of a new state-of-the-art self-report measure assessing all three negative emotional states in one brief instrument will benefit researchers and practitioners in a variety of health care and educational settings.
Cognitive Factors In Youth That Increase Vulnerability To Social Phobia
Funder
National Health and Medical Research Council
Funding Amount
$313,976.00
Summary
I am a psychologist focused on identifying the patterns of thinking of young people that make them vulnerable to developing a chronic and debilitating anxiety disorder known as social phobia. To do this, I will measure a range of thinking patterns of a sample of youth over time, and see which patterns are characteristic of those individuals who do develop social phobia. By identifying these particular thinking patterns, we will be able to identify youth who need preventative interventions.
The Centre will enhance Australian clinical immunisation research and training, focussing upon clinical questions with translatable outcomes not easily addressed by industry. Optimal immunisation and interventions to maximise uptake of existing and new vaccines in high risk patient groups, such as children with cancer, immigrants, children with chronic diseases and adolescents will be studied. New vaccine trials, innovative use of existing vaccines, systematic collection of vaccine failure data, ....The Centre will enhance Australian clinical immunisation research and training, focussing upon clinical questions with translatable outcomes not easily addressed by industry. Optimal immunisation and interventions to maximise uptake of existing and new vaccines in high risk patient groups, such as children with cancer, immigrants, children with chronic diseases and adolescents will be studied. New vaccine trials, innovative use of existing vaccines, systematic collection of vaccine failure data, and targeted epidemiology and disease modelling vaccine preventable disease will also allow a broad program of research, enabling training and mentoring of young clinical nurse and physician researchers. Collaborations with existing national immunisation, infectious diseases and research institutions will allow maximal effectiveness of clinical studies.Read moreRead less
The Effectiveness Of A School-based Parent Education Program In The Promotion Of Adolescent Health: A Randomised Trial
Funder
National Health and Medical Research Council
Funding Amount
$422,900.00
Summary
Youth mental health and behaviour problems such as depression, suicidal behaviour, tobacco use, alcohol abuse and illicit drug use are currently priority issues within Australian national and state public health policies. This project has been designed to contribute to knowledge on the effectiveness of interventions that can be used to prevent youth mental health and behaviour problems. Until recent years the development of programs to support families through the transition into adolescence has ....Youth mental health and behaviour problems such as depression, suicidal behaviour, tobacco use, alcohol abuse and illicit drug use are currently priority issues within Australian national and state public health policies. This project has been designed to contribute to knowledge on the effectiveness of interventions that can be used to prevent youth mental health and behaviour problems. Until recent years the development of programs to support families through the transition into adolescence has been neglected. This is remiss, as there is evidence that a range of youth mental health and behaviour problems may be preventable through interventions through this transition. The overall objective of this project is to evaluate the effectiveness of a multi-level, family intervention designed to promote adolescent health within secondary schools. The intervention will be implemented over the first two years of high school and incorporates both universal components (for all families) and selected components (for families with particular difficulties). The intervention elements have been developed and partially evaluated in work undertaken by the applicant and collaborators over the past five years. To evaluate this intervention a representative sample of 12 Victorian secondary schools will be randomly assigned to intervention and compared to 12 control schools with prior matching on school demographics and student behaviour variables. Intervention processes will be closely monitored and evaluated for impacts on relevant risk and protective factors. Effectiveness will be evaluated by testing whether reductions in youth mental health and behaviour problems were greater for intervention families compared to controls. The evaluation has been designed to test the theory that improvement across the whole secondary school environment can be encouraged by preventing the negative peer influences that can emerge within families experiencing adolescent adjustment problemsRead moreRead less