Integrated governance of water and coal seam gas. This project aims to evaluate the governance of the water effects on unconventional gas, to develop legal and policy principles for the integration of these effects in an effective, efficient and legitimate manner, and to investigate problems posed for integrated and polycentric governance, more generally. Australia must meet its unconventional gas needs without harming its water resources. The project is expected to deliver effective and legitim ....Integrated governance of water and coal seam gas. This project aims to evaluate the governance of the water effects on unconventional gas, to develop legal and policy principles for the integration of these effects in an effective, efficient and legitimate manner, and to investigate problems posed for integrated and polycentric governance, more generally. Australia must meet its unconventional gas needs without harming its water resources. The project is expected to deliver effective and legitimate outcomes for water, energy and potentially other social and environmental issues, aiming to establish Australia as a leader in sustainable water management.Read moreRead less
Increasing organisational capacity of community residential units to facilitate ageing in place for people with intellectual disability. Unique challenges face the disability, aged care and health sectors because of the increased life expectancy of people with life-long intellectual disability (ID) and the likelihood of their premature ageing. Although this group is recognised by Federal and State governments as requiring specific and special service arrangements, little is known about adapting ....Increasing organisational capacity of community residential units to facilitate ageing in place for people with intellectual disability. Unique challenges face the disability, aged care and health sectors because of the increased life expectancy of people with life-long intellectual disability (ID) and the likelihood of their premature ageing. Although this group is recognised by Federal and State governments as requiring specific and special service arrangements, little is known about adapting disability and aged care services to their needs. This research will inform the development of policy and programs in the disability, aged care, and health sectors. The research aims to improve the capacity of disability group homes to respond to the health and ageing issues of older people with ID,to improve their quality of life.Read moreRead less
Mitochondrially targeted anti-cancer drugs modulate the mitochondrial genome. Successful cancer management requires novel therapeutical approaches. This project will test the effect of a new class of compounds that target mitochondria, the powerhouse of the cells, where they suppress expression of mitochondrial genes. By this mechanism, cancers that are resistant to apoptosis induction can be inhibited.
Keeping my place in the community: achieving successful ageing-in-place for people with intellectual and developmental disabilities. This project, in partnership with aged care and disability agencies across two states, aims to examine ways the aged care, social and health needs of people with intellectual and developmental disabilities may be met in rural and urban settings. It will explore mechanisms that will lead to a better integration of the aged care and disability sectors.
The effect of wastewater treatment on the ecotoxicity of chiral chemicals. This project aims to assess the environmental implications of pharmaceuticals discharged in effluents from wastewater treatment plants. Trace levels of human pharmaceuticals occur in sewage and urban waterways, but during sewage treatment, some pharmaceuticals can undergo a chemical transformation known as 'chiral inversion'. In some cases, this may convert relatively benign environmental contaminants to more ecologically ....The effect of wastewater treatment on the ecotoxicity of chiral chemicals. This project aims to assess the environmental implications of pharmaceuticals discharged in effluents from wastewater treatment plants. Trace levels of human pharmaceuticals occur in sewage and urban waterways, but during sewage treatment, some pharmaceuticals can undergo a chemical transformation known as 'chiral inversion'. In some cases, this may convert relatively benign environmental contaminants to more ecologically toxic species. This project will investigate why and how some pharmaceuticals become susceptible to chiral inversion and assess ecotoxicological differences. This work is expected to determine the significance of considering chiral inversion in environmental risk assessment, with applications to a broader range of chemicals including pesticides and industrial chemicals.Read moreRead less
Impact Of DTP Schedules On The Immunogenicity Of 2 Doses Of 13v-PCV Followed By An Early Booster
Funder
National Health and Medical Research Council
Funding Amount
$2,651,687.00
Summary
This project aims to come up with a vaccination schedule to make pneumococcal vaccines more effective and affordable for Fiji and other developing countries. We will evaluate schedules involving a 2 dose primary series in early infancy with a booster at 9 months of age. We will compare the immune responses to 3 different primary series and 2 booster options. The results of this project will be used to provide advice, at global and country levels, regarding introduction of pneumococcal vaccines.
Most eye diseases have a genetic contribution, whether rare disorders affecting children such as retinoblastoma or congenital cataracts through to common disorders of older people such as myopia, age-related macular degeneration or glaucoma. We will continue our successful research to find genes that cause these diseases and use this to improve patient care and prevent blindness. We will work out how families can use this genetic information to participate in trials to develop new treatments.
Discovery Early Career Researcher Award - Grant ID: DE200100190
Funder
Australian Research Council
Funding Amount
$379,729.00
Summary
The effectiveness of impact investing for biodiversity conservation. This project aims to evaluate the effectiveness of impact investing for biodiversity conservation. Over $150 billion of private capital is invested worldwide to deliver social and environmental “impact” alongside a financial return. Impact investing promises “win-win-wins” for investors, governments and biodiversity alike, but also risks exacerbating accountability failures, transaction costs and conflicts of interest within hi ....The effectiveness of impact investing for biodiversity conservation. This project aims to evaluate the effectiveness of impact investing for biodiversity conservation. Over $150 billion of private capital is invested worldwide to deliver social and environmental “impact” alongside a financial return. Impact investing promises “win-win-wins” for investors, governments and biodiversity alike, but also risks exacerbating accountability failures, transaction costs and conflicts of interest within highly complex governance networks. This project seeks to discover factors that enable or inhibit the effectiveness of impact investing using a governance perspective. Project outcomes are expected to inform how impact investing may be harnessed to improve biodiversity conservation while minimising perverse outcomes.Read moreRead less
Activating employment futures through work integration social enterprise. This project aims to understand how Australia can better include people experiencing disadvantage in employment. Social enterprises are increasingly recognised for creating work and pathways into work for those who are typically excluded. Yet, little is known about how they can scale their operations and effectively transition workers into mainstream jobs, and what can be learned from social enterprise in designing other i ....Activating employment futures through work integration social enterprise. This project aims to understand how Australia can better include people experiencing disadvantage in employment. Social enterprises are increasingly recognised for creating work and pathways into work for those who are typically excluded. Yet, little is known about how they can scale their operations and effectively transition workers into mainstream jobs, and what can be learned from social enterprise in designing other inclusive workplaces. Underpinned by a unique learning partnership, this project is expected to shed light on how decent and inclusive work through social enterprise can be grown. Project insights will contribute to more effective employment services and workplaces that increase the shared benefits of a diverse workforce.Read moreRead less
Adequate nutrition is necessary for recovery from illness. 30-40% of hospitalised patients may be malnourished. The critically ill are at higher risk because of increased energy requirements yet often receive less than 50% of required nutritional intake. Adequate nutrition therapy is associated with improved patient outcomes, such as reduced mortality and reduced infectious complications. Robust strategies to implement of evidence-based recommendations for nutrition therapy are required.