Discovery Early Career Researcher Award - Grant ID: DE140101359
Funder
Australian Research Council
Funding Amount
$395,220.00
Summary
Hierarchical 3D metal organic frameworks for the microfabrication of advanced biomedical devices. This project will produce three-dimensional porous structures for use in sensing devices and biomedical implants. Metal-organic frameworks (MOFs) are versatile ultra high surface area materials with controllable pore size, chemical properties and functionalisation. These new materials will be incorporated into portable biosensing devices which are highly sensitive and reliable. The project involves ....Hierarchical 3D metal organic frameworks for the microfabrication of advanced biomedical devices. This project will produce three-dimensional porous structures for use in sensing devices and biomedical implants. Metal-organic frameworks (MOFs) are versatile ultra high surface area materials with controllable pore size, chemical properties and functionalisation. These new materials will be incorporated into portable biosensing devices which are highly sensitive and reliable. The project involves three streams including preparation of the three-dimensional metal scaffolds utilizing state-of-the-art direct manufacturing technologies; integration of MOFs on the three-dimensional metal scaffolds using the metallic structure as the source of the MOF metal ions; and incorporation of bio-active molecules into the three-dimensional hierarchically porous structure for the purpose of bio-device fabrication.Read moreRead less
Diamond Microneedles for Minimally Invasive Blood Collection. Blood sampling is a routine procedure for medical purposes to determine the physiological and biochemical status of patients. The aim of this project is to develop a reliable microneedle array for a blood collection procedures. Micro-scale needles for low-volume perforated blood samples are highly desirable due to its minimal invasiveness and painlessness. The miniaturization of sampling platforms driven by microneedles has the poten ....Diamond Microneedles for Minimally Invasive Blood Collection. Blood sampling is a routine procedure for medical purposes to determine the physiological and biochemical status of patients. The aim of this project is to develop a reliable microneedle array for a blood collection procedures. Micro-scale needles for low-volume perforated blood samples are highly desirable due to its minimal invasiveness and painlessness. The miniaturization of sampling platforms driven by microneedles has the potential to shift disease diagnosis and monitoring closer to the point of care. Expected outcomes include the development of synthetic diamond-based microneedles for the potential to greatly benefit society through improved and affordable healthcare and the development of new high-tech industries.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100166
Funder
Australian Research Council
Funding Amount
$240,000.00
Summary
Infrared and Raman microspectroscopic equipment for biomolecular and nanostructural analysis. This project will expand the combined microspectroscopic capabilities of Deakin and Monash Universities to enable high resolution characterisation of a diverse range of components in the fields of biotechnology and nanomaterials. The facility can be applied to pinpointing co-localised compounds within cells through to characterising metal composites, carbon nano tubes and fibres.
Bio-inspired conducting peptide nanowires for bioelectronic applications. Some bacteria possess a natural conductive tail constructed from proteins (called a nanowire) that has metal-like conductivity. The electrical signals in these nanowires are carried through aromatic groups in the peptides and/or attached cytochromes. This project addresses the design and assembly of conducting peptide-based fibrils inspired by these nanowires. It has already been shown that peptides can, by design, self-as ....Bio-inspired conducting peptide nanowires for bioelectronic applications. Some bacteria possess a natural conductive tail constructed from proteins (called a nanowire) that has metal-like conductivity. The electrical signals in these nanowires are carried through aromatic groups in the peptides and/or attached cytochromes. This project addresses the design and assembly of conducting peptide-based fibrils inspired by these nanowires. It has already been shown that peptides can, by design, self-assemble into long thermostable fibrils that support cell growth and development. The project’s goal is now to create cost-effective, non-toxic, conducting peptide fibrils that can be used in water or physiological environments for bioelectronics applications.Read moreRead less
Enhanced pigment weathering resistance by coating with high dielectric ceramic. The partner company, Tiwest, based in Western Australia, is a major contributor to the economy, and earns more than $A400m annually in exports. It is the only company in the world that mines, separates, refines and manufactures titania products, including pigments, in one region. The current post-titania particle formation wet-coating process, however, presents a major capital and recurrent cost and necessitates a pi ....Enhanced pigment weathering resistance by coating with high dielectric ceramic. The partner company, Tiwest, based in Western Australia, is a major contributor to the economy, and earns more than $A400m annually in exports. It is the only company in the world that mines, separates, refines and manufactures titania products, including pigments, in one region. The current post-titania particle formation wet-coating process, however, presents a major capital and recurrent cost and necessitates a pigment regrind stage. The research will investigate the development of a highly durable dry-coated pigment utilising a novel high dielectric coating. This development has the potential to ensure the partner company's future competitiveness through reduced processing costs and improved product performance.Read moreRead less
Cellulosic and paper-based biosensors for blood analysis. Testing the blood compatibility of an Australian evacuated for surgery; measuring the iron content from India for anemia treatment; identifying the outbreak of malaria in Pakistan; measuring prostate specific antigen/blood screening in your home. These are novel applications for paper biosensors, which will improve health and create new jobs in Australia.
Controlling Anisotropic Growth of Metal Oxide Crystals in Aqueous Solution by Selective Adsorption of Small Molecules. The proposed research will enhance our ability to make both light emitting diodes (LEDs) and piezoelectric actuators from ZnO. LEDs are a high efficiency light source that save energy compared to conventional illumination sources and can be fabricated in thin films. The proposal is to also bring the technology for device fabrication to Australia where it can ultimately be used ....Controlling Anisotropic Growth of Metal Oxide Crystals in Aqueous Solution by Selective Adsorption of Small Molecules. The proposed research will enhance our ability to make both light emitting diodes (LEDs) and piezoelectric actuators from ZnO. LEDs are a high efficiency light source that save energy compared to conventional illumination sources and can be fabricated in thin films. The proposal is to also bring the technology for device fabrication to Australia where it can ultimately be used to broaden the economic base of the country. The knowledge of crystal growth rate and crystal morphology control can be applied to improvements in the efficiency of alumina production which is already an important contributor to Australian exports.Read moreRead less
Hydrogen storage materials for energy conversion applications. For a clean environment, the ideal synthetic fuel is hydrogen because it is lightweight, highly abundant and its oxidation product (water) is environmentally benign. However, the effective storage of hydrogen remains a scientific challenge. This project aims to develop innovative materials with high hydrogen storage capacity and long cycle life, including new composite hydrides, catalysed metal hydrides and various nanotubes. The exp ....Hydrogen storage materials for energy conversion applications. For a clean environment, the ideal synthetic fuel is hydrogen because it is lightweight, highly abundant and its oxidation product (water) is environmentally benign. However, the effective storage of hydrogen remains a scientific challenge. This project aims to develop innovative materials with high hydrogen storage capacity and long cycle life, including new composite hydrides, catalysed metal hydrides and various nanotubes. The expected outcome is the achievement of high reversible hydrogen storage capacity to meet all the demands required for energy conversion applications, in particular, for hydrogen storage/fuel-cell vehicular applications.Read moreRead less
Wet Particulate Materials - Flow or Fracture? Most advanced materials are produced from starting materials in the form of fine particles. Powders, especially in ceramic engineering, are first processed wet into near-final shape. Improved understanding of the fracture of particle networks is critical in order to process nano-sized advanced ceramic materials for use in solar energy harvesting and extreme heat engine applications as well as minimising drying cracks in paints and coatings. The resea ....Wet Particulate Materials - Flow or Fracture? Most advanced materials are produced from starting materials in the form of fine particles. Powders, especially in ceramic engineering, are first processed wet into near-final shape. Improved understanding of the fracture of particle networks is critical in order to process nano-sized advanced ceramic materials for use in solar energy harvesting and extreme heat engine applications as well as minimising drying cracks in paints and coatings. The research aims to identify the fundamental link between particle network strength and structure and the fracture of wet powder bodies. The microscopic mechanisms that control the behaviour will be investigated with a particular focus on toughening mechanisms including the influence of plasticity.Read moreRead less
New Nanoscale Up-converting Photoluminescent Materials for Passive Safety Visual Systems. The demand for safety and security products is growing as the importance of providing an environment safer from natural, accidental or man-made threats increases in the community. Life safety applications in buildings and work environments as well as trains and planes for example are dependent upon the ability for non-powered passive systems to give efficient visual guidance in dangerous dark and smoke fill ....New Nanoscale Up-converting Photoluminescent Materials for Passive Safety Visual Systems. The demand for safety and security products is growing as the importance of providing an environment safer from natural, accidental or man-made threats increases in the community. Life safety applications in buildings and work environments as well as trains and planes for example are dependent upon the ability for non-powered passive systems to give efficient visual guidance in dangerous dark and smoke filled environments. This project will provide a practical demonstration of the successful implementation of nanotechnology to smaller Australian companies where it will overcome significant drawbacks in current manufacturing and yield new products which are activated in darkness by infrared radiation.Read moreRead less