Development of Control Methodologies for Drug Dosing in Biomedical Engineering. This research proposal is very relevant to the National Research Priorities in the areas of Frontier Technologies and Breakthrough science. At a broader level, we aim to assist in the development of a national competence in what has been an emerging and promising discipline. The research will develop fundamental and enabling laws and techniques for drug administration to regulate physiological variables such as blood ....Development of Control Methodologies for Drug Dosing in Biomedical Engineering. This research proposal is very relevant to the National Research Priorities in the areas of Frontier Technologies and Breakthrough science. At a broader level, we aim to assist in the development of a national competence in what has been an emerging and promising discipline. The research will develop fundamental and enabling laws and techniques for drug administration to regulate physiological variables such as blood pressure and degree of consciousness in critical care patients.Read moreRead less
Special Research Initiatives - Grant ID: SR0567658
Funder
Australian Research Council
Funding Amount
$100,000.00
Summary
A cross-disciplinary collaboration to develop a national system for real-time detection of Adverse Drug Reactions using linked Australian health data. Our aim is to use existing administrative health data in the evidence-based, cost-effective and privacy-respecting discovery of Adverse Drug Reactions. This research is of vital importance, since adverse reactions to medicines currently represent one of the leading causes of hospitalisation and death in Australia. In a groundbreaking collaboration ....A cross-disciplinary collaboration to develop a national system for real-time detection of Adverse Drug Reactions using linked Australian health data. Our aim is to use existing administrative health data in the evidence-based, cost-effective and privacy-respecting discovery of Adverse Drug Reactions. This research is of vital importance, since adverse reactions to medicines currently represent one of the leading causes of hospitalisation and death in Australia. In a groundbreaking collaboration, we have successfully shown that large linked, administrative data sets are sufficiently rich to enable discovery of adverse drug reactions, but our analytic tools are at an early developmental stage. The outcome of this project would be innovative, effective and sustainable analytic tools for the discovery of unexpected associations between drugs and medical events.Read moreRead less
Special Research Initiatives - Grant ID: SR0354797
Funder
Australian Research Council
Funding Amount
$20,000.00
Summary
The Australian Tissue Engineering Network. Driven by four key nodes across the country, the Initiative aims to bring together geographically and financially separated groups into a critical mass of cell and tissue engineering research. This new and rapidly-growing field uses a bio-synthetic approach to replace, repair or regenerate damaged tissues and organs. The Initiative will build the framework which will enable the Network to: identify appropriate expertise, manage duplication, enhance co ....The Australian Tissue Engineering Network. Driven by four key nodes across the country, the Initiative aims to bring together geographically and financially separated groups into a critical mass of cell and tissue engineering research. This new and rapidly-growing field uses a bio-synthetic approach to replace, repair or regenerate damaged tissues and organs. The Initiative will build the framework which will enable the Network to: identify appropriate expertise, manage duplication, enhance communication, bring together innovative skill sets, create linkages, generate focussed research programs and foster novel commercial opportunities. Ultimately the Initiative and Network will deliver an improved quality of life, reduced healthcare costs, and increased productivity to Australia.Read moreRead less
Uncovering The Basis Of Inflammatory And Immunodeficiency Diseases
Funder
National Health and Medical Research Council
Funding Amount
$15,718,075.00
Summary
A world-class team from 3 institutions, spanning disciplines of clinical and experimental immunology, therapeutics, signalling and genetics, will identify how immune and inflammatory responses are controlled in both health and disease. The major outcomes of this work will be the generation of new knowledge, concepts and approaches to diagnose, prevent and treat the major human health problems of autoimmune diseases, inflammation, allergy and immunodeficiency.
Cost Effective Pipeline Condition Assessment Using Paired Pressure Sensor Arrays. Water distribution networks represent society's most important infrastructure asset. They are buried pipes and are often old and deteriorating. Cost-effective methods to assess their physical condition are urgently needed. This research will develop a novel and advanced approach to determine the interior condition of pipes quickly and effectively using small water hammer pulses or waves. Paired pressure sensor arra ....Cost Effective Pipeline Condition Assessment Using Paired Pressure Sensor Arrays. Water distribution networks represent society's most important infrastructure asset. They are buried pipes and are often old and deteriorating. Cost-effective methods to assess their physical condition are urgently needed. This research will develop a novel and advanced approach to determine the interior condition of pipes quickly and effectively using small water hammer pulses or waves. Paired pressure sensor arrays will be used to measure reflections of the waves in pipes and these methods will enable finer resolution and identification of pipeline faults, such as wall thickness loss and leakage while at the same time allowing operational continuity. The outcome will be powerful tools to more cost effectively manage these crucial assets.Read moreRead less
Testosterone Intervention For The Prevention Of Diabetes Mellitus In High Risk Men: A Randomised Trial
Funder
National Health and Medical Research Council
Funding Amount
$5,054,654.00
Summary
Type 2 diabetes (T2DM) is increasingly common, costly and deadly. Some men at risk of T2DM have low testosterone (T) levels. Our preliminary data suggests that T treatment may prevent the development of T2DM, and improve cardiovascular and sexual function, body composition and bone density, and mood. This remains to be fully tested in a randomized placebo-controlled trial, and this project will do so in a 2-year study of T treatment compared to placebo in men at risk of T2DM participating in a l ....Type 2 diabetes (T2DM) is increasingly common, costly and deadly. Some men at risk of T2DM have low testosterone (T) levels. Our preliminary data suggests that T treatment may prevent the development of T2DM, and improve cardiovascular and sexual function, body composition and bone density, and mood. This remains to be fully tested in a randomized placebo-controlled trial, and this project will do so in a 2-year study of T treatment compared to placebo in men at risk of T2DM participating in a lifestyle program.Read moreRead less
Preparing Australia For Genomic Medicine: A Proposal By The Australian Genomics Health Alliance
Funder
National Health and Medical Research Council
Funding Amount
$25,000,000.00
Summary
The sequencing of the human genome brings the possibility of more accurate identification of the underlying basis of many diseases. This technology has moved so rapidly, however, that clinical access has been limited. In this application, a national alliance of clinicians, researchers, health economists and policymakers will evaluate the case for clinical genomics across inherited disease and cancer, determine how best to deliver this to the patient and train a capable workforce.
A 60% efficient solar microconcentrator for electricity and hot water. The aim of this project is to develop a microconcentrator for deployment on house roofs that will produce both solar hot water and solar electricity with a combined efficiency above 60%. The system will have a low profile and will be nearly invisible from the street. The system will track the sun. Concentration will be accomplished by a mixture of refraction and reflection. About 20% of the sunlight will be converted to elect ....A 60% efficient solar microconcentrator for electricity and hot water. The aim of this project is to develop a microconcentrator for deployment on house roofs that will produce both solar hot water and solar electricity with a combined efficiency above 60%. The system will have a low profile and will be nearly invisible from the street. The system will track the sun. Concentration will be accomplished by a mixture of refraction and reflection. About 20% of the sunlight will be converted to electricity using lines of tiny solar cells, with the balance being converted to heat which is removed by cooling fluid and stored in hot water tanks.Read moreRead less
Power systems with diverse generation - implications, control and capability. This research will generate a systematic methodology to handle the impact of the renewable energy sources on the NSW power grid. It increases our understanding of the impact of climate change policies relating to mandatory targets for greenhouse gas reduction helping to build Australia’s research capacity in the national priority area of an environmentally sustainable Australia. The anticipated methodology can also be ....Power systems with diverse generation - implications, control and capability. This research will generate a systematic methodology to handle the impact of the renewable energy sources on the NSW power grid. It increases our understanding of the impact of climate change policies relating to mandatory targets for greenhouse gas reduction helping to build Australia’s research capacity in the national priority area of an environmentally sustainable Australia. The anticipated methodology can also be seen as protecting the security of power infrastructure as well. Maintaining a critical energy infrastructure protects our way of life and ensures ongoing social, economic and environmental well being of Australia.Read moreRead less
Special Research Initiatives - Grant ID: SR0354551
Funder
Australian Research Council
Funding Amount
$20,000.00
Summary
ARC Research Network for Renewable Energy. The proposed Research Network will integrate and coordinate the entire research field of renewable energy in Australia. This Network covers a diverse range of technologies, and includes all prominent researchers in the area of renewable energy in Australia. The Network is strengthened by the inclusion of key people from government agencies, industry, industry associations and international research organisations.
Australia is a leading player in the ....ARC Research Network for Renewable Energy. The proposed Research Network will integrate and coordinate the entire research field of renewable energy in Australia. This Network covers a diverse range of technologies, and includes all prominent researchers in the area of renewable energy in Australia. The Network is strengthened by the inclusion of key people from government agencies, industry, industry associations and international research organisations.
Australia is a leading player in the world's renewable energy industry. An effective structure for networking and for the exchange of people, information and research results will maintain and improve Australia's position in this rapidly growing industry.Read moreRead less