Establishing advanced networks for air quality sensing and analyses. Establishing advanced networks for air quality sensing and analyses. This project aims to develop innovative, cost-effective, high resolution air quality networks. Recent developments in sensor technologies improve the ability to harvest atmospheric data. This project will develop, validate and implement methods for high sensitivity atmospheric sensing and apply cutting-edge statistical and analytic techniques to the data sets, ....Establishing advanced networks for air quality sensing and analyses. Establishing advanced networks for air quality sensing and analyses. This project aims to develop innovative, cost-effective, high resolution air quality networks. Recent developments in sensor technologies improve the ability to harvest atmospheric data. This project will develop, validate and implement methods for high sensitivity atmospheric sensing and apply cutting-edge statistical and analytic techniques to the data sets, unprecedented in scope and resolution. Outcomes include an open access database to quantify and visualise intra-urban air pollution and human exposure and develop air quality maps and smoke pollution management tools. It is expected to advance the evidence-based management of air as a resource, increasing economic prosperity and enhancing human health and quality of life.Read moreRead less
Which Heart Failure Intervention Is Most Cost Effective In Reducing Hospital Care (WHICH? II) Trial: A Multicentre, Randomised Trial Of Standard Versus Intensified Management Of Metropolitan And Regional-dwelling Patients With Heart Failure
Funder
National Health and Medical Research Council
Funding Amount
$1,891,210.00
Summary
Chronic heart failure (CHF) management programs are now the gold-standard to cost-effectively care for thousands of Australians hospitalised with CHF each year. We’ve shown that home-based management is most cost-effective in reducing hospital stay in CHF. The Which Intervention is most Cost-effective in reducing Hospital care (WHICH? II) Trial, a multicentre, randomised study, will determine if more intensive care (via home visits and remote care contacts) further improves poor outcomes in CHF.
Estimating per capita use and release of chemicals by wastewater analysis. This project aims to systematically collect and analyse wastewater to assess human exposure to chemicals including drugs, pharmaceuticals, lifestyle chemicals and environmental pollutants. By combining temporal sampling from key sewage treatment plants with comprehensive nationwide sampling over the week of the 2016 census day, the project expects to estimate the per-capita human exposure to chemicals in the Australian po ....Estimating per capita use and release of chemicals by wastewater analysis. This project aims to systematically collect and analyse wastewater to assess human exposure to chemicals including drugs, pharmaceuticals, lifestyle chemicals and environmental pollutants. By combining temporal sampling from key sewage treatment plants with comprehensive nationwide sampling over the week of the 2016 census day, the project expects to estimate the per-capita human exposure to chemicals in the Australian population. Accurate and objective per-capita based consumption and release estimates for a wide range of chemicals is intended to provide a baseline against which to measure changes in our chemosphere.Read moreRead less
Saving Nemo: Reducing animal use in toxicity assessments of wastewater. Every day, Australians produce ~5 billion litres of wastewater, which contains a cocktail of chemicals. Industries that discharge wastewater are required to assess chemical risks to the receiving environments by conducting whole animal direct toxicity assessments (DTA), which are expensive and pose an ethical dilemma. Our preliminary research shows that new in vitro bioassays provide an ethical and cost effective alternative ....Saving Nemo: Reducing animal use in toxicity assessments of wastewater. Every day, Australians produce ~5 billion litres of wastewater, which contains a cocktail of chemicals. Industries that discharge wastewater are required to assess chemical risks to the receiving environments by conducting whole animal direct toxicity assessments (DTA), which are expensive and pose an ethical dilemma. Our preliminary research shows that new in vitro bioassays provide an ethical and cost effective alternative that could be incorporated into DTA programs if their ecological relevance can be demonstrated. This project will develop and validate a new and internationally significant suite of in vitro bioassays for incorporation into DTA programs, leading to more ethical, cost effective and improved environmental protection.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE160100155
Funder
Australian Research Council
Funding Amount
$648,000.00
Summary
NanoMin; Quantitative Mineral Mapping of Nanoscale Processes. NanoMin: quantitative mineral mapping of nanoscale processes:
The project seeks to establish an electron microscope-based mineral mapping and analysis facility to provide rapid, quantitative and statistically reliable mineralogical, petrographic and metallurgical data unobtainable by other means in fine-grained materials. The proposed equipment can identify minerals in complex mixtures of sub-µm-grain size materials by virtue of an i ....NanoMin; Quantitative Mineral Mapping of Nanoscale Processes. NanoMin: quantitative mineral mapping of nanoscale processes:
The project seeks to establish an electron microscope-based mineral mapping and analysis facility to provide rapid, quantitative and statistically reliable mineralogical, petrographic and metallurgical data unobtainable by other means in fine-grained materials. The proposed equipment can identify minerals in complex mixtures of sub-µm-grain size materials by virtue of an integrated software and hardware system called NanoMin which incorporates a spectral deconvolution engine combined with a mineral spectra database. A key limitation in understanding complex materials is sub-micron to nanometer scale spatial variability of mineralogical phases. Imaging and quantifying these phases is now possible with the NanoMin system. This promises to open up petrological, geobiological, and materials science research in complex fine-grained materials.Read moreRead less
Unravelling how aquatic coastal networks regulate nitrogen removal . The aim of this project is to determine the nitrogen removal pathways of the coastal zone using a number of innovative field and modelling approaches. Little is known about how the complex coastal landscape controls trade-offs that maximise nitrogen removal but minimise nitrous oxide (a potent greenhouse gas) emissions. The outcomes of this study will significantly advance our understanding of the coastal zone in regional and g ....Unravelling how aquatic coastal networks regulate nitrogen removal . The aim of this project is to determine the nitrogen removal pathways of the coastal zone using a number of innovative field and modelling approaches. Little is known about how the complex coastal landscape controls trade-offs that maximise nitrogen removal but minimise nitrous oxide (a potent greenhouse gas) emissions. The outcomes of this study will significantly advance our understanding of the coastal zone in regional and global nitrogen budgets. This will provide significant benefits such as a new science-based quantitative framework to facilitate best practice management to reduce terrestrial nitrogen loads and associated downstream impacts such as eutrophication, and reduce nitrous oxide emissions and associated global warming.
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Airborne ultrafine particles in Australian cities. There is an acute deficiency of knowledge in Australia on urban airborne ultrafine particles, originating from transport and other anthropogenic sources, which pose significant health and environmental risks. The aim of this project is to address this deficiency by an extensive multi-city, cross-disciplinary study using state of the art instrumentation and data analytic techniques. The outcome will be an in depth, quantitative insight into the c ....Airborne ultrafine particles in Australian cities. There is an acute deficiency of knowledge in Australia on urban airborne ultrafine particles, originating from transport and other anthropogenic sources, which pose significant health and environmental risks. The aim of this project is to address this deficiency by an extensive multi-city, cross-disciplinary study using state of the art instrumentation and data analytic techniques. The outcome will be an in depth, quantitative insight into the characteristics of the particles, their sources and spatial and temporal variation across different urban areas and time scales. Further, the impacts of changing fuels, vehicle technologies, and climate on future trends of the particles will be elucidated.Read moreRead less
The Macroderma initiative: conserving ghost bats and informing development. This project aims to improve methods for capturing biological information required for environmental assessments of highly mobile species and enable strategic environmental planning in Northern Australia. Using Australia’s iconic ghost bat as a focus, the project will test and apply emerging technologies to obtain key information on a species’ population status and its critical resources to inform assessments of ecologic ....The Macroderma initiative: conserving ghost bats and informing development. This project aims to improve methods for capturing biological information required for environmental assessments of highly mobile species and enable strategic environmental planning in Northern Australia. Using Australia’s iconic ghost bat as a focus, the project will test and apply emerging technologies to obtain key information on a species’ population status and its critical resources to inform assessments of ecological impacts of industry development. Important benefits of the project include information and tools for streamlining development approvals and accurately assessing risks to threatened species to improve outcomes for both our economy and our natural environment.Read moreRead less
Quantifying the flux of fugitive greenhouse gasses associated with coal seam gas and calibrating it to natural baseline and anthropogenic sources. Recent studies show that fugitive methane emissions associated with coal seam gas extraction pose a source of greenhouse gasses. In addition to the possible environmental impacts of methane emissions, quantifying the magnitude of emissions has potentially significant implications for future tax liabilities that could change the economics of the unconv ....Quantifying the flux of fugitive greenhouse gasses associated with coal seam gas and calibrating it to natural baseline and anthropogenic sources. Recent studies show that fugitive methane emissions associated with coal seam gas extraction pose a source of greenhouse gasses. In addition to the possible environmental impacts of methane emissions, quantifying the magnitude of emissions has potentially significant implications for future tax liabilities that could change the economics of the unconventional energy boom in Australia. The proposed research by an interdisciplinary team representing regulators, industry, and university researchers would establish a methodology for quantifying the flux of methane from gas fields. It would establish the range of natural baselines and determine the major sources of methane emissions using newly available highly sensitive instruments.Read moreRead less
Probiotic Prawn Oral Immunotherapy (ProPIT) For Treatment Of Prawn Allergy
Funder
National Health and Medical Research Council
Funding Amount
$1,865,369.00
Summary
A ‘curative’ food allergy treatment is needed to prevent deaths and improve care. We recently showed that probiotic peanut oral immunotherapy (PPOIT) was highly effective for treating peanut allergy. 82% of PPOIT treated children gained tolerance compared to 4% of the placebo group. We will now test the combined probiotic-food OIT approach for treating prawn allergy. If successful, we will have identified the first treatment for prawn allergy and a platform treatment for other food allergies.