Optimising Prescribing In Older Australians: A Randomised Trial Of The Drug Burden Index With Home Medicines Review
Funder
National Health and Medical Research Council
Funding Amount
$96,436.00
Summary
The burden of polypharmacy in the older population is taking its toll. The average number of medicines prescribed to older Australians is on the rise, and in turn leading to increased significant costs to the public health system. Pharmacists have a crucial role to improve the quality use of medicines in older Australians. The Drug Burden Index measures a person’s total exposure to medicines. This project will evaluate the benefits of calculating the DBI for patients receiving Home Medicines Rev ....The burden of polypharmacy in the older population is taking its toll. The average number of medicines prescribed to older Australians is on the rise, and in turn leading to increased significant costs to the public health system. Pharmacists have a crucial role to improve the quality use of medicines in older Australians. The Drug Burden Index measures a person’s total exposure to medicines. This project will evaluate the benefits of calculating the DBI for patients receiving Home Medicines Reviews, conducted by pharmacists.Read moreRead less
Epidemiology, Diagnosis And Treatment Of Orthopaedic Infections
Funder
National Health and Medical Research Council
Funding Amount
$93,655.00
Summary
Orthopaedic surgery has led to significant improvements in patient's quality of life. With an ageing population, the number of patients requiring joint replacement and other bone and joint surgery will increase exponentially. Infection of the joint replacement is a devastating complication of this surgery. Research into these infections is still evolving. This research proposal aims to examine the clinical features of bone and joint infections, to explore ways to optimise diagnosis and improve t ....Orthopaedic surgery has led to significant improvements in patient's quality of life. With an ageing population, the number of patients requiring joint replacement and other bone and joint surgery will increase exponentially. Infection of the joint replacement is a devastating complication of this surgery. Research into these infections is still evolving. This research proposal aims to examine the clinical features of bone and joint infections, to explore ways to optimise diagnosis and improve treatment and outcomes for patients.Read moreRead less
Improving Access To Optimal Clinical Care For People With Chronic Hepatitis B Through The Implementation Of A Nurse-led Model Of Care
Funder
National Health and Medical Research Council
Funding Amount
$176,250.00
Summary
Chronic hepatitis B (CHB) is a global public health issue. Best practice guidelines indicate that early diagnosis and treatment can reduce mortality, however, guidelines are not being followed because uptake of management and treatment is low. This project aims to address the gap between optimal and current CHB management through implementation of a nursing service, which will build capacity, and target the need for improved management for this vulnerable group of patients.
Improving Oesophageal Adenocarcinoma Outcomes Through Understanding Genomics And Treatment Toxicity.
Funder
National Health and Medical Research Council
Funding Amount
$1,013,282.00
Summary
Oesophageal adenocarcinoma is an aggressive cancer, as most patients will not survive for more than 5 years. Therefore we need to find better ways to treat patients. In this study we will identify the DNA mutations in oesophageal cancers that were part of clinical trial. The data allow us to determine why some tumours responded well to therapy, and why some patients had serious side effects to the treatment. The results will help inform on selection of therapy for future patients.
Application Of Genomic Technologies For The Diagnosis And Management Of Genetic Heart Diseases.
Funder
National Health and Medical Research Council
Funding Amount
$438,768.00
Summary
The purpose of this research study is to investigate clinical and genetic factors which may predispose to important cardiac events such as dangerous arrhythmias, heart failure, heart transplantation or sudden cardiac death in patients with genetic heart diseases. It is possible that there are important risk factors or genetic findings which may be identified either through newer technologies which help cardiologists determine which patients and families are most at risk.
Reducing Falls By Improving Knowledge Translation: A Mixed-methods Study To Incorporate Falls Prevention Best-practice Evidence Into Osteoarthritis Care
Funder
National Health and Medical Research Council
Funding Amount
$88,502.00
Summary
Over 50% of people with osteoarthritis (OA) will fall. Resources exist to assist clinicians in the management of OA, but give little or no attention to falls.The association between OA and falls supports the need to incorporate falls prevention strategies into routine OA care. This project aims to reduce falls and fall-related harm in people with OA by creating a list of recommendations for preventing falls that can be incorporated into current OA resources and routine OA care.
Which Heart Failure Intervention Is Most Cost Effective In Reducing Hospital Care (WHICH? II) Trial: A Multicentre, Randomised Trial Of Standard Versus Intensified Management Of Metropolitan And Regional-dwelling Patients With Heart Failure
Funder
National Health and Medical Research Council
Funding Amount
$1,891,210.00
Summary
Chronic heart failure (CHF) management programs are now the gold-standard to cost-effectively care for thousands of Australians hospitalised with CHF each year. We’ve shown that home-based management is most cost-effective in reducing hospital stay in CHF. The Which Intervention is most Cost-effective in reducing Hospital care (WHICH? II) Trial, a multicentre, randomised study, will determine if more intensive care (via home visits and remote care contacts) further improves poor outcomes in CHF.
Centre Of Research Excellence: Partnering With Patients With Chronic Kidney Disease To Transform Care And Outcomes (CRE-PACT)
Funder
National Health and Medical Research Council
Funding Amount
$2,500,000.00
Summary
CRE-PACT will partner with patients to generate and translate new high-priority evidence to improve outcomes that are important to people living with chronic kidney disease (CKD). We will address the topics and questions most important to patients. We will build the next generation of research leaders and a community of research-ready patient-partners. There will be an integrated pathway for evidence translation and implementation at a global scale to improve patient-centred outcomes.
Enhancing Communication Between Medical Oncologists And Patients With Advanced Malignancy Considering Clinical Trial Participation, With A Focus On CALD Populations
Funder
National Health and Medical Research Council
Funding Amount
$92,335.00
Summary
In the advanced stages of cancer, some patients will need to choose between multiple options - they might wish to pay for an expensive but unfunded drug, they may consider taking part in a clinical trial or opt to stay at home and focus on the time they have. This project will aim to help patients make these difficult decisions with their clinicians, and will have a focus on those from culturally and linguistically diverse backgrounds as they face additional barriers to trial entry.