Patients' preference for participation in patient safety activities. This study will identify patient and nurse perceptions of involving patients in patient safety activities. Priorities for implementing strategies to support patient participation in patient safety activities will be identified, which will influence both health policy and practice.
Regulation of lung immune-epithelial networks sensing environmental change. This study aims to uncover how lung epithelial cells engage with immune cells and determine their cellular and molecular wiring to ensure homeostatic maintenance and essential repair processes of lung tissues. Maintenance of lung epithelial-immune networks is essential to maintain normal lung tissue structure and function, and to induce immune responses to protect against microbial challenges or inhaled potentially toxic ....Regulation of lung immune-epithelial networks sensing environmental change. This study aims to uncover how lung epithelial cells engage with immune cells and determine their cellular and molecular wiring to ensure homeostatic maintenance and essential repair processes of lung tissues. Maintenance of lung epithelial-immune networks is essential to maintain normal lung tissue structure and function, and to induce immune responses to protect against microbial challenges or inhaled potentially toxic substances. Understanding this molecular program of epithelial-immune cell-mediated sensing/repair will be essential to understand how tissue-repair processes can be driven in the lung, an organ critical for respiration and thus life.Read moreRead less
Understanding influences on physical activity and sedentary behaviour from preschool to preadolescence. While promotion of optimal levels of physical activity and sedentary behaviours during childhood is important for health, much remains unknown in this field. This study will extend an existing cohort of children, recruited at ages three to five years and followed up at six to eight years by reassessing these children at nine to eleven years. Novel additions to the cohort include long term foll ....Understanding influences on physical activity and sedentary behaviour from preschool to preadolescence. While promotion of optimal levels of physical activity and sedentary behaviours during childhood is important for health, much remains unknown in this field. This study will extend an existing cohort of children, recruited at ages three to five years and followed up at six to eight years by reassessing these children at nine to eleven years. Novel additions to the cohort include long term follow-up spanning preschool to preadolescence, application of an ecological framework, and collection of objective neighbourhood data using a Geographical Information System. Findings will provide important information for policy and interventions focused at the individual, family and neighbourhood level, to improve physical activity and sedentary behaviour levels across childhood.Read moreRead less
Very young adolescents and substance use: community and family vulnerabilities and healthy developmental transitions. This research will examine how families and communities protect very young children from early alcohol and tobacco use. The findings will lead to new prevention policies and programs that better meet the needs of vulnerable communities. This project will strengthen collaborations with leading international research centres in this area.
Molecular toxinology of Australia's lesser known venomous snakes. This proposal represents a tremendous opportunity for biodiscovery from venomous snakes. This will be achieved through the researchers' unique approach of investigating previously unmapped venom systems for divergent, bioactive proteins. An understanding of venomous animal protein evolution great potential in drug discovery and other commercial applications. This project will provide Australian graduate and post-graduate stude ....Molecular toxinology of Australia's lesser known venomous snakes. This proposal represents a tremendous opportunity for biodiscovery from venomous snakes. This will be achieved through the researchers' unique approach of investigating previously unmapped venom systems for divergent, bioactive proteins. An understanding of venomous animal protein evolution great potential in drug discovery and other commercial applications. This project will provide Australian graduate and post-graduate students with finely tuned skills in cutting edge methodological techniques and a fluent understanding of molecular evolution, preparing them to be internationally competitive scientists.Read moreRead less
Muscle fibre excitability and calcium regulation in skeletal muscle of amphibians and mammals. The fundamental role of skeletal muscle is posture and movement. Essential for this is a specialised cell structure and a complex regulation of function. This project will define key aspects of muscle structure and functional regulation crucial to developing targets for improving function under stressed states such as fatigue, disease and age.
Demonstrating the feasibility of designing sustainable buildings using evolutionary systems. The design approach proposed in this research will result in two key areas of national benefit. First, the research will enable Australian built environment design professions to become more competitive in both domestic and international markets. There is a growing demand for environmentally-friendly buildings and the proposed design approach will enable Australian firms to be at the cutting edge of sust ....Demonstrating the feasibility of designing sustainable buildings using evolutionary systems. The design approach proposed in this research will result in two key areas of national benefit. First, the research will enable Australian built environment design professions to become more competitive in both domestic and international markets. There is a growing demand for environmentally-friendly buildings and the proposed design approach will enable Australian firms to be at the cutting edge of sustainable design. Second, the research will enable the Australian built environment to become more sustainable. The proposed approach will enable buildings to be designed that perform well, that are cost effective and that minimise their environmental impact. Read moreRead less
The Impact of Sexual and Gender-Based Violence on the Dynamics of Conflict. This project aims to understand the impact of sexual and gender-based violence on the dynamics of conflict. With an innovative mixed method design it will study all reported incidences of sexual and gender-based violence in 41 conflict-affected countries between 1998 and 2018. It will generate new knowledge establishing how and when crimes of sexual and gender-based violence affect the onset and intensity of conflict. Th ....The Impact of Sexual and Gender-Based Violence on the Dynamics of Conflict. This project aims to understand the impact of sexual and gender-based violence on the dynamics of conflict. With an innovative mixed method design it will study all reported incidences of sexual and gender-based violence in 41 conflict-affected countries between 1998 and 2018. It will generate new knowledge establishing how and when crimes of sexual and gender-based violence affect the onset and intensity of conflict. The expected outcomes of this project include the identification of the most high-risk situations, the phases of violence, and the improvement of risk assessments for such violence. The project will significantly benefit the prevention of sexual and gender-based violence in conflict-affected situations globally.Read moreRead less
Preventing Mass Sexual and Gender-based Violence in Conflict and Non-Conflict Affected Countries. Widespread and systematic Sexual and Gender Based Violence (SGBV) has been recognised by the United Nations Security Council since 2000 as a matter of international peace and security. Under the 1998 Rome Statute it is a crime against humanity, a war crime and an act of genocide. There are two explanations for mass SGBV: the presence of armed conflict and the existence of extreme gender inequality a ....Preventing Mass Sexual and Gender-based Violence in Conflict and Non-Conflict Affected Countries. Widespread and systematic Sexual and Gender Based Violence (SGBV) has been recognised by the United Nations Security Council since 2000 as a matter of international peace and security. Under the 1998 Rome Statute it is a crime against humanity, a war crime and an act of genocide. There are two explanations for mass SGBV: the presence of armed conflict and the existence of extreme gender inequality and oppression prior to onset of conflict. Yet, to date, there is little knowledge of how variations in the type of conflict and gender inequality contribute to SGBV crimes. This project will test and refine the two dominant and competing explanations for SGBV crimes to inform strategies for the prevention of SGBV where risk is high.Read moreRead less
Civilian Protection and the Use of Force in UN Peacekeeping Operations. This project seeks to evaluate the use of force to protect civilians in United Nations peacekeeping. United Nations peacekeepers are on the frontline of efforts to protect civilians from violence. More than 100 were killed in 2014. Hundreds of thousands of civilians depend on peacekeepers for their safety. To date, however, there has been little systematic evaluation of the impact of the use of force for civilian protection ....Civilian Protection and the Use of Force in UN Peacekeeping Operations. This project seeks to evaluate the use of force to protect civilians in United Nations peacekeeping. United Nations peacekeepers are on the frontline of efforts to protect civilians from violence. More than 100 were killed in 2014. Hundreds of thousands of civilians depend on peacekeepers for their safety. To date, however, there has been little systematic evaluation of the impact of the use of force for civilian protection mandates on both immediate protection goals and the wider goals of peacekeeping. This project aims to assess the impact of the implementation of mandates to use force to protect civilians. Through a focused comparison of six missions, it plans to identify what works, what doesn't, and the factors which determine these outcomes in order to identify ways of improving performance in the future.Read moreRead less