Which Heart Failure Intervention Is Most Cost Effective In Reducing Hospital Care (WHICH? II) Trial: A Multicentre, Randomised Trial Of Standard Versus Intensified Management Of Metropolitan And Regional-dwelling Patients With Heart Failure
Funder
National Health and Medical Research Council
Funding Amount
$1,891,210.00
Summary
Chronic heart failure (CHF) management programs are now the gold-standard to cost-effectively care for thousands of Australians hospitalised with CHF each year. We’ve shown that home-based management is most cost-effective in reducing hospital stay in CHF. The Which Intervention is most Cost-effective in reducing Hospital care (WHICH? II) Trial, a multicentre, randomised study, will determine if more intensive care (via home visits and remote care contacts) further improves poor outcomes in CHF.
Clinical And Psychosocial Changes Over Late Childhood And Adolescence And Early Life Determinants Of Long Term Clinical Outcomes In Cystic Fibrosis
Funder
National Health and Medical Research Council
Funding Amount
$1,135,570.00
Summary
Cystic fibrosis is the most common life shortening inherited disease in Caucasians. Lung damage starts in infancy and lung function falls most rapidly in adolescence although why and how this happens and early life determinants are not known. This study takes advantage of a previous study that monitored young children from 3 months to 5 years of life and follows them closely through early adolescence to investigate the protective and risk factors for falling lung function.
Probiotic Prawn Oral Immunotherapy (ProPIT) For Treatment Of Prawn Allergy
Funder
National Health and Medical Research Council
Funding Amount
$1,865,369.00
Summary
A ‘curative’ food allergy treatment is needed to prevent deaths and improve care. We recently showed that probiotic peanut oral immunotherapy (PPOIT) was highly effective for treating peanut allergy. 82% of PPOIT treated children gained tolerance compared to 4% of the placebo group. We will now test the combined probiotic-food OIT approach for treating prawn allergy. If successful, we will have identified the first treatment for prawn allergy and a platform treatment for other food allergies.
Preparing Australia For Genomic Medicine: A Proposal By The Australian Genomics Health Alliance
Funder
National Health and Medical Research Council
Funding Amount
$25,000,000.00
Summary
The sequencing of the human genome brings the possibility of more accurate identification of the underlying basis of many diseases. This technology has moved so rapidly, however, that clinical access has been limited. In this application, a national alliance of clinicians, researchers, health economists and policymakers will evaluate the case for clinical genomics across inherited disease and cancer, determine how best to deliver this to the patient and train a capable workforce.
Forgiveness in conflict resolution and peacebuilding: international dimensions. In an age in which ongoing conflicts and tensions have very real ramifications for international and regional security, finding new and more effective ways to resolve international disputes is critical to ensuring Australia's ongoing security. This project will therefore benefit Australia by 'enhancing our nation's understanding of social, political, and cultural issues' associated with the resolution of conflict in ....Forgiveness in conflict resolution and peacebuilding: international dimensions. In an age in which ongoing conflicts and tensions have very real ramifications for international and regional security, finding new and more effective ways to resolve international disputes is critical to ensuring Australia's ongoing security. This project will therefore benefit Australia by 'enhancing our nation's understanding of social, political, and cultural issues' associated with the resolution of conflict in the Asia Pacific region. By helping to develop an alternative peacebuilding tool, it will also assist those engaged in the practical delivery of peacebulding initiatives in the region.Read moreRead less
Special Research Initiatives - Grant ID: SR0354734
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
The Australian Research Network for Medical Devices: advanced technology solutions for patients and practitioners. Medical Device technologies embrace a wide range of scientific, engineering and medical knowledge, with the goal of assisting a clinical professional (doctor or nurse) deliver a service to a patient in an efficacious, cost effective manner. Development of appropriate medical devices, whether for diagnosis, treatment or prevention of disease or disability, is critical to improving h ....The Australian Research Network for Medical Devices: advanced technology solutions for patients and practitioners. Medical Device technologies embrace a wide range of scientific, engineering and medical knowledge, with the goal of assisting a clinical professional (doctor or nurse) deliver a service to a patient in an efficacious, cost effective manner. Development of appropriate medical devices, whether for diagnosis, treatment or prevention of disease or disability, is critical to improving health care and reducing health care costs. To be successful, a device must include all relevant disciplines in the research, development and testing phases. This network will bring together these groups, promoting knowledge sharing and cross-disciplinary investigations that illuminate current device limitations and potential solutions.Read moreRead less
Strengthening community partnerships to promote adolescent school engagement and prevent problems such as alcohol misuse and violence. The project will reduce community rates of adolescent school non-attendance, adolescent alcohol misuse and antisocial behaviour. Adolescent school exclusion, alcohol use and antisocial behaviour are highly prevalent in Australia, and can be reduced using a variety of strategies that are coordinated at the school and community level. The project will decrease adol ....Strengthening community partnerships to promote adolescent school engagement and prevent problems such as alcohol misuse and violence. The project will reduce community rates of adolescent school non-attendance, adolescent alcohol misuse and antisocial behaviour. Adolescent school exclusion, alcohol use and antisocial behaviour are highly prevalent in Australia, and can be reduced using a variety of strategies that are coordinated at the school and community level. The project will decrease adolescent problems through community improvements in child and adolescent protective influences and reductions in risk influences. Furthermore, the project will equip communities with the capacity to learn how to identify and implement strategies to address the major influences that have the potential to reduce adolescent behaviour problems.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989067
Funder
Australian Research Council
Funding Amount
$950,000.00
Summary
The future of palaeoclimate and archaeological research in Australia: next generation instrumentation for chronology and environmental reconstruction. The outcomes of this project will promote a better understanding of Australia's arid continent and its surrounding marine environment, contribute to studies of global climate change, and provide new insights into the response of fragile ecosystems to such events and processes. The project addresses directly the National Research Priority 'Water - ....The future of palaeoclimate and archaeological research in Australia: next generation instrumentation for chronology and environmental reconstruction. The outcomes of this project will promote a better understanding of Australia's arid continent and its surrounding marine environment, contribute to studies of global climate change, and provide new insights into the response of fragile ecosystems to such events and processes. The project addresses directly the National Research Priority 'Water - a critical resource', 'Responding to climate change and variability', 'Overcoming soil loss, salinity and acidity', 'Sustainable use of Australia's biodiversity' and 'Understanding our region and the world'. It provides a consortium-type platform for highly productive collaborative research and training across eight universities and one research organisation in Australia.Read moreRead less
A process model of visual working memory. This project aims to develop a process model of encoding of items into memory. Working memory is central to almost all cognitive functions, but little is known about short-term memory for visual information. Progress in this area is slow because of a focus on models that do not specify the processes underlying memory, and no model explains the processes that would limit the number of items the memory can hold to four. A process model is expected to addre ....A process model of visual working memory. This project aims to develop a process model of encoding of items into memory. Working memory is central to almost all cognitive functions, but little is known about short-term memory for visual information. Progress in this area is slow because of a focus on models that do not specify the processes underlying memory, and no model explains the processes that would limit the number of items the memory can hold to four. A process model is expected to address fundamental issues in visual working memory.Read moreRead less
Strengthening Australia's national integrity system. Strengthening Australia's national integrity system. This project aims to equip governments and civil society stakeholders with evidence-based options to improve the structure and operations of integrity institutions, by undertaking a second National Integrity System Assessment. Public integrity is vital to social and economic prosperity and the quality of democracy. This project intends to identify new, more effective strategies to prevent co ....Strengthening Australia's national integrity system. Strengthening Australia's national integrity system. This project aims to equip governments and civil society stakeholders with evidence-based options to improve the structure and operations of integrity institutions, by undertaking a second National Integrity System Assessment. Public integrity is vital to social and economic prosperity and the quality of democracy. This project intends to identify new, more effective strategies to prevent corruption and other integrity violations; coordinate the work of integrity institutions; ensure their accountability; and measure the effectiveness of integrity and anti-corruption policy settings. This research is expected to contribute to better evaluation of integrity policies worldwide.Read moreRead less