Memory and the temporal lobes. This project will use brain imaging techniques to investigate how humans perceive, combine and access stored knowledge about the world via different senses. This information will not only provide information on normal brain processes, but will also provide vital data on what happens to memory if certain regions of the brain become damaged.
The early communicative environment prior to and following cochlear implants: impact on children's early communicative and cognitive development. This research with children with cochlear implants will examine the effect on language development of being in an oral environment or one that also includes sign language. The outcomes will provide information for parents and professionals enabling informed decision about the management of the children to promote the best possible outcomes.
The Material Science of Biomimetic Soft Network Composites. Nature combines stiff and strong collagen fibres intertwined within a weak polymer matrix of proteoglycans into soft tissues with outstanding mechanical durability and biological properties. We converge a biomimetic design strategy inspired in the architecture of natural soft tissues and a novel additive manufacturing technology termed melt electrowriting (MEW) to manufacture advanced biomimetic soft network composites (BSNC). The SNCs ....The Material Science of Biomimetic Soft Network Composites. Nature combines stiff and strong collagen fibres intertwined within a weak polymer matrix of proteoglycans into soft tissues with outstanding mechanical durability and biological properties. We converge a biomimetic design strategy inspired in the architecture of natural soft tissues and a novel additive manufacturing technology termed melt electrowriting (MEW) to manufacture advanced biomimetic soft network composites (BSNC). The SNCs are composed of a weak polymer matrix and a MEW reinforcing fibrous phase printed at the nanometre scale, containing patterns mimicking the natural tissue architectures. Advanced computational tools are applied for the rational design of the SNC while reducing costs and times associated to experimental work.Read moreRead less
Regulation of lung immune-epithelial networks sensing environmental change. This study aims to uncover how lung epithelial cells engage with immune cells and determine their cellular and molecular wiring to ensure homeostatic maintenance and essential repair processes of lung tissues. Maintenance of lung epithelial-immune networks is essential to maintain normal lung tissue structure and function, and to induce immune responses to protect against microbial challenges or inhaled potentially toxic ....Regulation of lung immune-epithelial networks sensing environmental change. This study aims to uncover how lung epithelial cells engage with immune cells and determine their cellular and molecular wiring to ensure homeostatic maintenance and essential repair processes of lung tissues. Maintenance of lung epithelial-immune networks is essential to maintain normal lung tissue structure and function, and to induce immune responses to protect against microbial challenges or inhaled potentially toxic substances. Understanding this molecular program of epithelial-immune cell-mediated sensing/repair will be essential to understand how tissue-repair processes can be driven in the lung, an organ critical for respiration and thus life.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0347727
Funder
Australian Research Council
Funding Amount
$400,000.00
Summary
Computational infrastructure for high-throughput genome bioinformatics. We propose a high-performance computing and web facility for genome bioinformatics. It will provide a common software development environment in support of molecular biosciences, systems biology and complex systems modelling at the Institute for Molecular Bioscience at University of Queensland, and at Queensland University of Technology. The platform will support Australia's first genome-scale bioinformatics research website ....Computational infrastructure for high-throughput genome bioinformatics. We propose a high-performance computing and web facility for genome bioinformatics. It will provide a common software development environment in support of molecular biosciences, systems biology and complex systems modelling at the Institute for Molecular Bioscience at University of Queensland, and at Queensland University of Technology. The platform will support Australia's first genome-scale bioinformatics research website, with unique software and mirrors of the IBM Biological Pattern Discovery, UC San Diego MEME/MetaMEME/MAST, and NGI comparative genomics websites. Australian/NZ researchers will access the facility at no cost for high-throughput use of unique software, website mirrors and other important tools for genome bioinformatics.Read moreRead less
Special Research Initiatives - Grant ID: SR0354605
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
The Earth System Dynamics Network for a Sustainable Australia. Earth comprises systems of enormous complexity that sustain all life and control the distribution of mineral, energy and water resources. Thus understanding these dynamic systems provides the key to sustainable resource usage. The aim of The Earth System Dynamics Network is to facilitate scientific interactions through establishment of an earth and environmental sciences grid that links national and regional data assets with high per ....The Earth System Dynamics Network for a Sustainable Australia. Earth comprises systems of enormous complexity that sustain all life and control the distribution of mineral, energy and water resources. Thus understanding these dynamic systems provides the key to sustainable resource usage. The aim of The Earth System Dynamics Network is to facilitate scientific interactions through establishment of an earth and environmental sciences grid that links national and regional data assets with high performance computing through open sourced middleware. The result will be an unparalleled predictive capacity for complex Earth systems. The outcome will be confidence in the knowledge that underpins our decisions as stakeholders to keep Australia sustainable.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE200100235
Funder
Australian Research Council
Funding Amount
$422,241.00
Summary
The impact of mass gathering events on emergency healthcare services. Mass gathering events (MGEs) occur frequently across Australia. The preparation of a MGE from an emergency healthcare service perspective is conducted with limited evidence to support decision-making. Using routinely collected data from Tourism and Events Queensland, Queensland Ambulance Service, Queensland Emergency Departments, and the Bureau of Meteorology, this research aims to determine the impact on ambulance and emergen ....The impact of mass gathering events on emergency healthcare services. Mass gathering events (MGEs) occur frequently across Australia. The preparation of a MGE from an emergency healthcare service perspective is conducted with limited evidence to support decision-making. Using routinely collected data from Tourism and Events Queensland, Queensland Ambulance Service, Queensland Emergency Departments, and the Bureau of Meteorology, this research aims to determine the impact on ambulance and emergency department services in the vicinity of 750 planned MGEs over a five year period (2015 - 2019). The expected outcome includes an enhanced ability to predict the required emergency healthcare services for a MGE, therefore enhancing the planning and response, benefiting MGE attendees and the MGE host community.Read moreRead less
Functionally characterizing mammalian microRNAs and mRNA interactions controlling cell division. This project addresses some of the most burning issues in molecular biology and genetic research, and the results will be widely applicable to a broad range of fields, including biotechnology, animal breeding, agricultural production, genetic engineering, medical science, and computational biology. By understanding the regulatory potential of microRNA molecules, we will understand more about species ....Functionally characterizing mammalian microRNAs and mRNA interactions controlling cell division. This project addresses some of the most burning issues in molecular biology and genetic research, and the results will be widely applicable to a broad range of fields, including biotechnology, animal breeding, agricultural production, genetic engineering, medical science, and computational biology. By understanding the regulatory potential of microRNA molecules, we will understand more about species diversity, regulatory networks, and plant and animal development. The early adoption of multi-gigabase next-generation sequencing technology in Australia provides rare and exciting opportunity to lead the world in genome-scale research, and to ensure that Australia has the necessary skill base to remain internationally competitive in this field.Read moreRead less
Nanoparticle from urban transport: Quantification of formation and dynamics for application for health and environmental risk reduction. Socio-economic benefits of the project outcomes to Australia: (i) advancing the fundamental understanding of the processes contributing to the adverse environmental impacts of nanoparticles; (ii) provision of vital information on the reduction of the environmental and health risks of nanoparticles, thus contributing to the goal of 'cleaner, safer combustion'; ( ....Nanoparticle from urban transport: Quantification of formation and dynamics for application for health and environmental risk reduction. Socio-economic benefits of the project outcomes to Australia: (i) advancing the fundamental understanding of the processes contributing to the adverse environmental impacts of nanoparticles; (ii) provision of vital information on the reduction of the environmental and health risks of nanoparticles, thus contributing to the goal of 'cleaner, safer combustion'; (iii) placing Australian researchers in the frontline of nanoparticle science and technology and international progress towards sustainable development; and (iv) lowering of human exposure to nanoparticles in the cities of tomorrow, thus reducing health care costs and lost productivity. Read moreRead less
QUANTIFICATION OF INTERACTIONS DURING THE DISPERSION OF CORONA IONS AND AIRBORNE PARTICLES NEAR POWER LINES. Currently there is no method for quantification of concentration and dispersion of charged aerosols near high voltage power lines (HVPLs). However, hypothesis have been presented, but not yet proven scientifically, that residents of houses close to combustion sources such as highways or industrial plants and HVPLs may be subjected to health risk due to inhalation of charged aerosols. The ....QUANTIFICATION OF INTERACTIONS DURING THE DISPERSION OF CORONA IONS AND AIRBORNE PARTICLES NEAR POWER LINES. Currently there is no method for quantification of concentration and dispersion of charged aerosols near high voltage power lines (HVPLs). However, hypothesis have been presented, but not yet proven scientifically, that residents of houses close to combustion sources such as highways or industrial plants and HVPLs may be subjected to health risk due to inhalation of charged aerosols. The outcome of this project will be a model for quantitative assessment of the processes occurring during the transport and dispersion of corona ions and combustion aerosol, which will be a tool for predictive risk assessment and informed management of public resources in relation to power line design and maintenance.Read moreRead less