Listen to me, I really am sick! Understanding patient and family perspectives in triggering responses to medical emergencies. This project investigates whether patient and family perspectives are treated as evidence of a deteriorating health state whilst in hospital. Recommendations from this study will inform the development of patient centred strategies to reduce delays in clinician response to physiological deterioration and improve patient safety in hospitals.
The global vaccination revolution: a transnational and comparative perspective. A study of first global immunization campaign will provide a historical dimension to contemporary concerns about pandemic disease, vaccination and bio-terrorism, and generate new insights into the factors determining the success and failure of public health initiatives. The project relates directly to national research priorities in health and safeguarding Australia. It has more specific relevance to Australia. Small ....The global vaccination revolution: a transnational and comparative perspective. A study of first global immunization campaign will provide a historical dimension to contemporary concerns about pandemic disease, vaccination and bio-terrorism, and generate new insights into the factors determining the success and failure of public health initiatives. The project relates directly to national research priorities in health and safeguarding Australia. It has more specific relevance to Australia. Smallpox decimated the Aboriginal population, and quarantine and vaccination have loomed large in Australian history. It builds on Australia's strong scholarship in the fields of virology and immunology and the history of disease and public health.Read moreRead less
The World Arm-to-Arm: The Spread of Smallpox Vaccination and Global Networks of Knowledge and Power, 1799-1805. This project will document the rapid spread of Jenner's vaccine around the world between 1799 and 1805. It will address matters neglected in the existing literature, including the logistics of the global transmission of the vaccine, often literally arm-to-arm; the promotion and reception of vaccination in different social and cultural contexts; and the networks of power and knowledge ....The World Arm-to-Arm: The Spread of Smallpox Vaccination and Global Networks of Knowledge and Power, 1799-1805. This project will document the rapid spread of Jenner's vaccine around the world between 1799 and 1805. It will address matters neglected in the existing literature, including the logistics of the global transmission of the vaccine, often literally arm-to-arm; the promotion and reception of vaccination in different social and cultural contexts; and the networks of power and knowledge that made the Jennerian revolution possible. The project will result in a book and articles, interventions in the literature on globalisation and the adoption of innovation, and a deeper and broader perspective on issues of burning relevance to the world today.Read moreRead less
From risk factor analysis to translation: multiple sclerosis and vitamin D deficiency. This research on multiple sclerosis will focus on its causes and lifestyle factors that affect it and will trial vitamin D supplementation as a treatment. Studies on vitamin D deficiency in healthy populations aim to develop new public health recommendations on sun exposure and vitamin D that balance risk of skin cancer against vitamin D deficiency.
Critical windows: understanding changes in eating and physical activity over the transition from secondary school to young adulthood. This project will explain changes in eating, physical activity and sedentary behaviour during the critical period of transition from secondary school to young adulthood. It will provide important information on how we can assist adolescents to maintain a healthy lifestyle over a time characterised by several major life changes.
Improving Stroke Outcomes: Attenuating Progression And Recurrence
Funder
National Health and Medical Research Council
Funding Amount
$9,331,996.00
Summary
Stroke is the second most common cause of death and major cause disability. There are few proven interventions, so we need to introduce new ones. We developed a bench to bedside program to introduce new stroke therapies and its early secondary prevention. Our general goal is to provide evidence for their effectiveness and safety. We will use animal stroke models, markers in the blood to help diagnose and predict stroke outcome and imaging to help select patients for several clinical trials.
The effects of maternal attachment, marital satisfaction and sensitivity to infants on infants attachment and adjustment: A longitudinal-structural equation study. This study will examine how family and attachment factors effect the adjustment of infant at 24 months of age. A longitudinal study, using structural equation method, will examine how maternal attachment and marital satisfaction when infants are 4 months of age will effect maternal parenting behaviors two months later, and how all thr ....The effects of maternal attachment, marital satisfaction and sensitivity to infants on infants attachment and adjustment: A longitudinal-structural equation study. This study will examine how family and attachment factors effect the adjustment of infant at 24 months of age. A longitudinal study, using structural equation method, will examine how maternal attachment and marital satisfaction when infants are 4 months of age will effect maternal parenting behaviors two months later, and how all three of these measures will effect infant attachment 6 months later. It will then examine how all four of these measures will effect the adjustment of infants 12 months later. The study will have important implications for early intervention and prevention of psychological problems in infants and children.Read moreRead less
Translational research in osteoarthritis: from epidemiological studies to clinical interventions. Currently the only treatment for osteoarthritis is to relieve pain. However, there are some factors that may affect the progression of this disease. This project will examine these factors including inflammation, metabolism, and physical inactivity, and find potential modifying therapies such as vitamin D supplementation for osteoarthritis.
A Biologically Responsive and Anatomically Authentic Human Nasal Model. As respiratory conditions caused by pollutants and viruses become more prevalent, human nasal models to study infection/protection mechanisms and nasal drug/vaccine delivery are increasingly important. This project aims to develop a world-first human nasal model to mimic both anatomical and biological aspects of the nasal cavity and predict the distribution and deposition of fine particles and the resultant biological respon ....A Biologically Responsive and Anatomically Authentic Human Nasal Model. As respiratory conditions caused by pollutants and viruses become more prevalent, human nasal models to study infection/protection mechanisms and nasal drug/vaccine delivery are increasingly important. This project aims to develop a world-first human nasal model to mimic both anatomical and biological aspects of the nasal cavity and predict the distribution and deposition of fine particles and the resultant biological response from the nasal mucosa. The aim is to overcome a key fabrication challenge - to 3D print an anatomically accurate nasal construct with a porous wall on which to grow and mature functional nasal tissue that lines a nasal cavity wall. The benefit would be enabling faster development of more targeted drugs and vaccines.Read moreRead less
Program evaluation of the osteoarthritis awareness hub. Persons with osteoarthritis generally have poor knowledge about their disease and its appropriate management. The aim of this project is to evaluate whether improved knowledge, and management decisions of persons with osteoarthritis, can ultimately lead to improved health outcomes.