A Genome-wide Association Study In 2000 Glaucoma Cases With Matched Controls Using Equimoloar DNA Pools
Funder
National Health and Medical Research Council
Funding Amount
$610,267.00
Summary
Glaucoma is a common cause of loss of vision worldwide but we are unable to predict which people are at high risk of blindness. We aim to discover the genetic risk factors for glaucoma. We will use cutting edge genetic technology to assess the whole genome in thousands of patients with glaucoma. We hope to identify important new glaucoma genes, which could lead to the development of diagnostic tests and treatments which will provide the most cost-efficient ways to prevent glaucoma blindness.
Devising sophisticated computational comparative genomic analysis strategies for animal and plant genomes. Given the significance of comparative genomic analysis, this research proposal brings together Australian scientists with a track record in comparative genomic analysis, bioinformatics, molecular biology and statistics to work on consolidating a computational framework for comparative genomic analysis and investigating transcriptome data by capitalising on international collaborations and i ....Devising sophisticated computational comparative genomic analysis strategies for animal and plant genomes. Given the significance of comparative genomic analysis, this research proposal brings together Australian scientists with a track record in comparative genomic analysis, bioinformatics, molecular biology and statistics to work on consolidating a computational framework for comparative genomic analysis and investigating transcriptome data by capitalising on international collaborations and involvement. The outcomes of this research will be of benefit to the national community through technology transfer (such as the identification of novel and functional genomic non-coding sequences), training (in bioinformatics related activities) and national coordination (of bioinformatics activities).Read moreRead less