Application Of Protein Microarrays To Develop A Cross-Species Malaria Vaccine
Funder
National Health and Medical Research Council
Funding Amount
$451,821.00
Summary
Malaria remains a significant public health problem worldwide. Five species of malaria parasites infect humans. The ideal vaccine would be effective against all five species. Using a novel protein microarray approach, we will identify Plasmodium proteins that may be excellent targets of a cross-species malaria vaccine. This research will build on Australia's current strengths in biotechnology and will result in significant economic benefits by facilitating the development of a malaria vaccine.
Long-term Implications And Outcomes Of Anti Hepatitis B Virus (HBV) Treatment In HIV-HBV Co-infection
Funder
National Health and Medical Research Council
Funding Amount
$293,931.00
Summary
Chronic hepatitis B (HBV) infection may cause serious liver disease in some people, including liver failure or liver cancer. Being infected with both HBV and HIV increases the chances of these complications occurring and the rate they develop. The optimal long term management of HIV-HBV co-infection remains unclear; and the effects of antiretroviral therapy on liver disease progression outcome is unknown in the setting of HIV-HBV co-infection.