A philosophical and empirical approach to the nature of perception and belief. This project offers substantial benefits - intellectual, practical, and ultimately economic - to the nation. On the intellectual side, the project will contribute to research output and will further enhance the national research strength in the study of delusions, rationality, and agency, within both philosophy of mind and inter-disciplinary cognitive science. On the practical side, the project offers the prospect of ....A philosophical and empirical approach to the nature of perception and belief. This project offers substantial benefits - intellectual, practical, and ultimately economic - to the nation. On the intellectual side, the project will contribute to research output and will further enhance the national research strength in the study of delusions, rationality, and agency, within both philosophy of mind and inter-disciplinary cognitive science. On the practical side, the project offers the prospect of considerable benefits for the community as improved theories of the nature and causes of delusions generate strategies for earlier detection or even prevention of the development of delusions, new methods of therapy for patients, and better understanding for families.Read moreRead less
THE EFFECT OF STRESS AND ENVIRONMENTAL ENRICHMENT ON DISEASE PROGRESSION IN MESIAL TEMPORAL LOBE EPILEPSY
Funder
National Health and Medical Research Council
Funding Amount
$578,201.00
Summary
Mesial temporal lobe epilepsy, the most common form of drug-resistant epilepsy in adults, is a progressive neurodegenerative condition for which there is currently no effective disease modifying treatment. This proposal will explore whether co-morbid stress accelerates disease progression in MTLE, and whether targeting stress pathways by medical and environmental manipulations can mitigate against this.
Personal Identity, Consciousness and Agency. If I lose my memory, am I the same person I used to be? If much of my body or brain is replaced, do I remain the same person? What if my beliefs and attitudes are altered: does this affect who I am? These are questions of personal identity, and they have enormous bearing on questions of public ethics, especially in the light of biomedical changes. Our inter-disciplinary solutions will add both nuance and insight to the difficult decisions the communit ....Personal Identity, Consciousness and Agency. If I lose my memory, am I the same person I used to be? If much of my body or brain is replaced, do I remain the same person? What if my beliefs and attitudes are altered: does this affect who I am? These are questions of personal identity, and they have enormous bearing on questions of public ethics, especially in the light of biomedical changes. Our inter-disciplinary solutions will add both nuance and insight to the difficult decisions the community will face in this area. The project brings to Australia two leading young researchers from the United States, thus substantially enhancing Australia's skill base and international profile.Read moreRead less
From autobiographical memory to collective memory: An interdisciplinary study of individual and group cognition. Remembering our past is crucial to our identity and well-being, both as individuals and in groups. Investigating the role of social groups in memory, this project offers 4 benefits: (1) it builds Australia's capacity for high-level, innovative memory research; (2) it pioneers an interdisciplinary approach, genuinely integrating philosophy and psychology, to strengthen Australia's inte ....From autobiographical memory to collective memory: An interdisciplinary study of individual and group cognition. Remembering our past is crucial to our identity and well-being, both as individuals and in groups. Investigating the role of social groups in memory, this project offers 4 benefits: (1) it builds Australia's capacity for high-level, innovative memory research; (2) it pioneers an interdisciplinary approach, genuinely integrating philosophy and psychology, to strengthen Australia's international reputation in these fields; (3) it identifies social supports for healthy remembering, thus 'Promoting and Maintaining Good Health' ('Ageing well, ageing productively'); (4) it offers fresh, sophisticated ways to address public debates about the role of memory in productive, fulfilling lives, 'Strengthening Australia's social and economic fabric'.Read moreRead less
Language, belief formation and visual cognition: cognitive and neuropsychological investigations. I will direct a programme of research and research training in cognitive science and cognitive neuropsychology at macquarie universtiy, with international collaborative links to the USA, Canada, France, Italy, Spain, Germany & New Zealand. This programme of research and research training will initially focus on
a)how people understand and produce language, and how these capabilities can break down ....Language, belief formation and visual cognition: cognitive and neuropsychological investigations. I will direct a programme of research and research training in cognitive science and cognitive neuropsychology at macquarie universtiy, with international collaborative links to the USA, Canada, France, Italy, Spain, Germany & New Zealand. This programme of research and research training will initially focus on
a)how people understand and produce language, and how these capabilities can break down after brain damage;
b)The relationship between visual memory and reading; and
c)The nature of the delusions seen in schizophrenia and other disorders, and what causes these delusions.Read moreRead less
Inhibition Of Fear Memories By Extinction: Neural Substrates.
Funder
National Health and Medical Research Council
Funding Amount
$234,250.00
Summary
Anxiety disorders [e.g., Post Traumatic Stress Disorder (PTSD)] are the most prevalent type of psychopathology in the industrialised world. They are associated with characteristic behavioural (e.g., heightened startle) and autonomic (e.g., cardiovascular) reactions. These disorders are often characterised as an inability to regulate the emotion of fear. Significant progress has been made in understanding the neural and cellular processes involved in the establishment of fear memories, but relati ....Anxiety disorders [e.g., Post Traumatic Stress Disorder (PTSD)] are the most prevalent type of psychopathology in the industrialised world. They are associated with characteristic behavioural (e.g., heightened startle) and autonomic (e.g., cardiovascular) reactions. These disorders are often characterised as an inability to regulate the emotion of fear. Significant progress has been made in understanding the neural and cellular processes involved in the establishment of fear memories, but relatively little is known about the mechanisms by which fear memories can be inhibited or suppressed. Understanding this latter process is a key to the development of effective treatments for anxiety disorders such as PTSD where the patient suffers from persistent, intrusive, unwanted trauma memories. A common experimental procedure for reducing learned fear is to repeatedly expose the subject to a fear-eliciting stimulus but without any aversive outcome. This procedure leads to a progressive loss, or extinction, of the fear reactions elicited by the stimulus. Historically, the extinction of fear was thought to be due to an erasure of the fear memory. However, recent evidence shows that extinction inhibits, rather than erases, the fear memory. Because the fear memories remain intact, some structure(s) in the brain must inhibit activity in the fear pathway. This project uses extinction of conditioned fear reactions in rat subjects to determine the structure(s) in the brain that inhibit fear memories and their behavioural and cardiovascular expression. It brings together the expertise of four well-established researchers and uses a combination of behavioural, physiological, immunohistochemical, tract tracing, and lesion approaches to achieve this aim. The proposed experiments will reveal the structure(s) in the brain that control the inhibition of fear, as well as the site(s) of this inhibition in the fear pathwayRead moreRead less
Concepts and Conceptual Change. Aim: To develop a new theory of conceptual change that explains how a concept can change considerably, while still remaining in a crucial sense the very same concept.
Significance: All areas of philosophy need to solve this problem so as to distinguish between real and merely verbal disputes. There is no adequate solution to this long standing problem.
Outcomes: A general solution to the problem, with applications to areas including ethics, philosophy of con ....Concepts and Conceptual Change. Aim: To develop a new theory of conceptual change that explains how a concept can change considerably, while still remaining in a crucial sense the very same concept.
Significance: All areas of philosophy need to solve this problem so as to distinguish between real and merely verbal disputes. There is no adequate solution to this long standing problem.
Outcomes: A general solution to the problem, with applications to areas including ethics, philosophy of consciousness, metaphysics and political theory.
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'As-if thinking': an experimental analysis of human reasoning and decision-making. The failure to respond adequately to the havoc wreaked by Hurricane Katrina in 2005 highlighted the difficulty of sequential decision-making. Responses to such emergencies require detailed contingency plans, necessitating a consideration of all possible outcomes of a situation regardless of their objective probability. This project takes an innovative approach to the experimental analysis of human reasoning and de ....'As-if thinking': an experimental analysis of human reasoning and decision-making. The failure to respond adequately to the havoc wreaked by Hurricane Katrina in 2005 highlighted the difficulty of sequential decision-making. Responses to such emergencies require detailed contingency plans, necessitating a consideration of all possible outcomes of a situation regardless of their objective probability. This project takes an innovative approach to the experimental analysis of human reasoning and decision-making, with the aim of identifying the mechanisms, factors, and boundary conditions affecting inferences and decisions about uncertain alternatives. The research will inform planning for Australia's readiness to respond to unpredictable events with uncertain outcomes and enhance the reputation of Australian science.Read moreRead less
Music cognition in infants, children and adults. Music is an important tool for the expression of emotion and transmission of culture. One approach to understanding why music is a human universal is to examine how people process musical structure - the simultaneous and sequential pitch relations among tones of musical pieces. We investigate the way humans acquire implicit and explicit knowledge of such relations and the way exposure to music influences acquisition. Three experiments involving in ....Music cognition in infants, children and adults. Music is an important tool for the expression of emotion and transmission of culture. One approach to understanding why music is a human universal is to examine how people process musical structure - the simultaneous and sequential pitch relations among tones of musical pieces. We investigate the way humans acquire implicit and explicit knowledge of such relations and the way exposure to music influences acquisition. Three experiments involving infants, children and adults will compare formal musical training with incidental learning. Results will increase knowledge of the development of auditory perception and music cognition. Infant perceptual predispositions hold implications for music education.Read moreRead less
Associability processes in propositional learning. A novel attentional model of learning is evaluated in this project. In this model, learning is seen not as a consequence of a low-level, evolutionarily old system shared with our ancestors, but as a product of our capacity to apply rules and engage in reasoning. Understanding the role of attention in learning will allow a better understanding of the attentional biases seen in clinical disorders such as addiction and a new way to think about the ....Associability processes in propositional learning. A novel attentional model of learning is evaluated in this project. In this model, learning is seen not as a consequence of a low-level, evolutionarily old system shared with our ancestors, but as a product of our capacity to apply rules and engage in reasoning. Understanding the role of attention in learning will allow a better understanding of the attentional biases seen in clinical disorders such as addiction and a new way to think about the neuroscience of attention. These benefits may further suggest new lines of research in the development of drugs to combat attentional disorders.Read moreRead less