Microfluidic models of the CNS: Understanding cells, circuits & synapses. Aims: We aim to develop new cell culture platforms to form defined networks of brain cells. These platforms will be used to determine the critical mechanisms underpinning central nervous system function.
Significance: The devices developed will enable an unprecedented capacity to monitor changes throughout a network, with analysis at the level of the synapse, cell and circuit.
Expected outcomes: We will advance knowledge ....Microfluidic models of the CNS: Understanding cells, circuits & synapses. Aims: We aim to develop new cell culture platforms to form defined networks of brain cells. These platforms will be used to determine the critical mechanisms underpinning central nervous system function.
Significance: The devices developed will enable an unprecedented capacity to monitor changes throughout a network, with analysis at the level of the synapse, cell and circuit.
Expected outcomes: We will advance knowledge regarding the function of the CNS and deliver complex human cellular systems, that have both discovery and commercial applications.
Benefit: These platforms will have subsequent application revealing the mechanisms underlying numerous neurological diseases, with capacity to upscale for rapid drug screening.
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How do Changes in Institutional Memory Affect Public Policy Processes? . This project will analyse how changes in institutional memory inside government impact on the effectiveness of public policy processes. Institutional memory changes as ministers, public servants and public agencies come and go, but we don’t know what effect these changes have over the quality of public policy. This project will therefore analyse how changes to institutional memory have influenced public services and polici ....How do Changes in Institutional Memory Affect Public Policy Processes? . This project will analyse how changes in institutional memory inside government impact on the effectiveness of public policy processes. Institutional memory changes as ministers, public servants and public agencies come and go, but we don’t know what effect these changes have over the quality of public policy. This project will therefore analyse how changes to institutional memory have influenced public services and policies in Australia and the UK. Expected outcomes include best practice recommendations for government - about how to address memory loss to improve public policy - and novel academic findings about how institutional memory influences the character of public service delivery, lesson-learning and long-term reform.Read moreRead less
A Buddhist Debate and Its Contemporary Relevance. The aim of this project is to engage with one of the central debates in Tibetan philosophy concerning truth, realism and epistemic justification. It plans to explore the implications of this debate for subsequent Tibetan thought and for contemporary Western analytic philosophy. The project plans to analyse previously unstudied texts and demonstrate the fecundity of a traditional method of collaborative cross-cultural philosophy today in which Tib ....A Buddhist Debate and Its Contemporary Relevance. The aim of this project is to engage with one of the central debates in Tibetan philosophy concerning truth, realism and epistemic justification. It plans to explore the implications of this debate for subsequent Tibetan thought and for contemporary Western analytic philosophy. The project plans to analyse previously unstudied texts and demonstrate the fecundity of a traditional method of collaborative cross-cultural philosophy today in which Tibetan and Western scholars work together to develop joint analyses. It may also demonstrate that the metaphysical and epistemological ideas and arguments developed in these debates can contribute to Western philosophy.Read moreRead less
Cabinet Government in comparative perspective. This project explores how cabinet government is, or is not, able to develop a collective will. Cabinets lie at the heart of parliamentary systems, but public and academic analyses question whether they work effectively. Using examples of majoritarian and consensus democratic regimes, this project plans to examine how cabinets work and identify the different functions cabinet plays in developing collective views of policy or political situations. The ....Cabinet Government in comparative perspective. This project explores how cabinet government is, or is not, able to develop a collective will. Cabinets lie at the heart of parliamentary systems, but public and academic analyses question whether they work effectively. Using examples of majoritarian and consensus democratic regimes, this project plans to examine how cabinets work and identify the different functions cabinet plays in developing collective views of policy or political situations. The project expects to illustrates how the different appreciations of cabinet, whether seen as constitutional or operational, or in terms of policy analysis or political contests, help define the values of cabinet and can allow us to understand in what circumstances cabinet government is important in terms of stability and sensible policy. It asks if collective cabinets like Australia's can survive in the 21st century.Read moreRead less
Empowering Aboriginal & Torres Strait Islander Girls, Changing Communities. This project applies Indigenous knowledges to develop new understandings and insights in the area of Aboriginal and Torres Strait Islander girls’ education. Expected outcomes of the project include: the development of a national framework that supports the education of girls and acknowledges the importance of self-determination, culture, gender and place in creating life changing educational opportunities; addressing Clo ....Empowering Aboriginal & Torres Strait Islander Girls, Changing Communities. This project applies Indigenous knowledges to develop new understandings and insights in the area of Aboriginal and Torres Strait Islander girls’ education. Expected outcomes of the project include: the development of a national framework that supports the education of girls and acknowledges the importance of self-determination, culture, gender and place in creating life changing educational opportunities; addressing Close the Gap targets; and creating broader long lasting positive changes regarding access, participation and success for Aboriginal and Torres Strait Islander students. The outcomes of this project can provide significant benefits to the broad Australian schooling system.Read moreRead less
Reducing environmental footprint by improving phosphorous use efficiency. While modern agriculture relies heavily on the use of phosphorous fertilizers, most of them are not used by plants and lost in runoff, resulting in a massive environmental damage through contamination of waterways (termed eutrophication). This project takes advantage of an untapped resource - a unique collection of Tibetan wild barley genotypes, to reveal key traits that confer superior phosphorus use efficiency in wild ba ....Reducing environmental footprint by improving phosphorous use efficiency. While modern agriculture relies heavily on the use of phosphorous fertilizers, most of them are not used by plants and lost in runoff, resulting in a massive environmental damage through contamination of waterways (termed eutrophication). This project takes advantage of an untapped resource - a unique collection of Tibetan wild barley genotypes, to reveal key traits that confer superior phosphorus use efficiency in wild barley and identify appropriate candidate genes and their position on chromosomes for further incorporating these traits into commercial barley cultivars. This will reduce the environmental footprint of modern agricultural practices on terrestrial and aquatic ecosystems without compromising food security.Read moreRead less
The future of forests under climatic stress. This project aims to measure the vulnerability of forest trees to more extreme drought as global temperatures inevitably rise. Australian forests face the immediate threat of increased mortality associated with intensifying drought stress in the future. Understanding the magnitude of this threat is of the utmost urgency. This project aims to predict future mortality of forest communities in Australia and worldwide using recent breakthroughs enabling t ....The future of forests under climatic stress. This project aims to measure the vulnerability of forest trees to more extreme drought as global temperatures inevitably rise. Australian forests face the immediate threat of increased mortality associated with intensifying drought stress in the future. Understanding the magnitude of this threat is of the utmost urgency. This project aims to predict future mortality of forest communities in Australia and worldwide using recent breakthroughs enabling the rapid quantification of lethal stress in trees. This new understanding will provide a basis upon which to make far-reaching decisions about land management, conservation and restoration.Read moreRead less
How plants open up: revealing the evolution of stomatal opening mechanisms. This project aims to identify novel and conserved mechanisms that drive the opening of stomata – plant pores that enable CO2 acquisition for photosynthesis. Stomatal movements strongly affect plant productivity and water use efficiency and have profoundly influenced the earth’s climate and terrestrial ecology. This project will address critical gaps in our understanding of how plants open stomata in response to their env ....How plants open up: revealing the evolution of stomatal opening mechanisms. This project aims to identify novel and conserved mechanisms that drive the opening of stomata – plant pores that enable CO2 acquisition for photosynthesis. Stomatal movements strongly affect plant productivity and water use efficiency and have profoundly influenced the earth’s climate and terrestrial ecology. This project will address critical gaps in our understanding of how plants open stomata in response to their environment and the evolutionary history of the genes controlling this fundamental process. A major expected outcome is knowledge of the diversity of stomatal opening pathways, which should ultimately lead to improved predictions of plant responses to environmental change and assist future targeted modification of plant growth.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH190100014
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
ARC Research Hub for Sustainable Onshore Lobster Aquaculture. The project aims to build knowledge to establish the world’s first sustainable onshore lobster aquaculture industry focused on commercial, sustainable and socially responsible lobster production from hatchery to market. The project will investigate novel systems engineering, specialised feed manufacture, determination and modification of seedstock quality, new frontiers in seedstock transport, all within an informed environmental and ....ARC Research Hub for Sustainable Onshore Lobster Aquaculture. The project aims to build knowledge to establish the world’s first sustainable onshore lobster aquaculture industry focused on commercial, sustainable and socially responsible lobster production from hatchery to market. The project will investigate novel systems engineering, specialised feed manufacture, determination and modification of seedstock quality, new frontiers in seedstock transport, all within an informed environmental and marketing framework. The project will provide alternate solutions for lobster culture in bio-secure and cost effective onshore systems. The outcomes are targeted at positioning Australia at the forefront of onshore lobster aquaculture, with opportunity for technology transfer to other aquaculture sectors.Read moreRead less