Nanoliposomal delivery of docosahexaenoic acid (DHA) to neuronal cells. Omega-3 fatty acids such as docosahexaenoic acid (DHA) are essential for brain function. They are effective as adjunct treatments for depression, but at high doses. The project will develop nanoliposomes to target delivery of DHA to brain cells. Efficient delivery of DHA to brain cells will increase its effectiveness as a dietary supplement and lessen the burden of disease.
A prospective investigation of self-injury, suicidal ideation and psychological distress in Australian secondary school students. Suicide prevention has been a national priority for the past 10 years. Self-injury is a predictor of suicide, results in considerable distress for family and friends and is associated with significant health care expenditure. In addition the known correlates of self-injury, such as depression and substance use, also pose significant burden to society and are themselve ....A prospective investigation of self-injury, suicidal ideation and psychological distress in Australian secondary school students. Suicide prevention has been a national priority for the past 10 years. Self-injury is a predictor of suicide, results in considerable distress for family and friends and is associated with significant health care expenditure. In addition the known correlates of self-injury, such as depression and substance use, also pose significant burden to society and are themselves predictors of suicide. Understanding the nature and extent of self-injury in Australian adolescents, and the causal relationships between self-injury, suicidal ideation and psychological distress, will improve the care given to those who self-injure, improve their well-being, decrease their chances of further self-injury, and decrease the chance they will die by suicide.Read moreRead less
Who determines gestation length - mother or fetus? This project will extend our knowledge of a key biological process - pregnancy. Variation of gestation length by 10% is generally deleterious to the offspring, and smaller babies have been shown to be more susceptible to later life diseases. Therefore, extension of the information gained from this project will likely impact researchers in species conservation, pest control, and the livestock industries, as well as human, obstetric care and pract ....Who determines gestation length - mother or fetus? This project will extend our knowledge of a key biological process - pregnancy. Variation of gestation length by 10% is generally deleterious to the offspring, and smaller babies have been shown to be more susceptible to later life diseases. Therefore, extension of the information gained from this project will likely impact researchers in species conservation, pest control, and the livestock industries, as well as human, obstetric care and practice. Specifically, knowledge gained from this project may lead to means of limiting (pest control) as well as enhancing (endangered species) species survival.Read moreRead less
The development of emotion regulation strategies and their relationships with psychological wellbeing: A long-term follow-up study. A largely neglected area, emotion regulation in young people will be comprehensively examined. The first of its kind worldwide, this research will provide a rich understanding of the development of emotion regulation over the course of development from late childhood to early adulthood. An understanding of the role played by emotion regulation in wellbeing will prov ....The development of emotion regulation strategies and their relationships with psychological wellbeing: A long-term follow-up study. A largely neglected area, emotion regulation in young people will be comprehensively examined. The first of its kind worldwide, this research will provide a rich understanding of the development of emotion regulation over the course of development from late childhood to early adulthood. An understanding of the role played by emotion regulation in wellbeing will provide important foundations for the development of intervention and prevention strategies that incorporate emotional functioning processes. This is predicted to result in a marked increase in the efficacy of existing prevention and intervention efforts which will lead to significant health care cost savings and social benefits, particularly for our youth.Read moreRead less
Shaping the heart in early development - new insights into cellular modelling processes. Heart health is an important contributor to quality of life and longevity. This research will provide new insights into the way hormonal influences early in development shape a healthy heart. The project builds on the application of recently patented, sophisticated cell imaging techniques. Research students and trainees recruited to this project will benefit from their involvement with this leading edge tech ....Shaping the heart in early development - new insights into cellular modelling processes. Heart health is an important contributor to quality of life and longevity. This research will provide new insights into the way hormonal influences early in development shape a healthy heart. The project builds on the application of recently patented, sophisticated cell imaging techniques. Research students and trainees recruited to this project will benefit from their involvement with this leading edge technology. These studies are important in providing a basis for developing optimal management strategies for congenital heart conditions and preterm infants. Improved knowledge of the cardiac effects of fetal and neonatal exposure to steroids (to assist with lung maturation in prematurity or to control maternal asthma) will be gained.Read moreRead less
Playing it Safe: Psychological Safety and Mental Health for Community Sport. At a time when over half of all Australians participate in organised sports it is critical to ensure that these environments are psychologically safe. The problem is that community sports clubs have no clear guidance on how to fulfil this substantial responsibility. There have been urgent calls for the development of psychological safety and mental health guidelines which have yet to be answered. This project will deliv ....Playing it Safe: Psychological Safety and Mental Health for Community Sport. At a time when over half of all Australians participate in organised sports it is critical to ensure that these environments are psychologically safe. The problem is that community sports clubs have no clear guidance on how to fulfil this substantial responsibility. There have been urgent calls for the development of psychological safety and mental health guidelines which have yet to be answered. This project will deliver the knowledge to underpin effective psychological safety and mental health guidelines for community sports with national impact. When implemented, this knowledge will help sports clubs to provide a psychologically safe environment, and promote the mental health and wellbeing of all Australians involved in organised sports.Read moreRead less
Paving the way for effective public health interventions for bulimic eating disorders: Understanding stigma and mental health literacy. This research contributes to promoting and maintaining good health. The burden of bulimic eating disorders in the community is high, frequently ignored and increasing. Our research will pave the way for improved understanding of eating disorders and a reduction of stigma in relation to these problems. In so doing, it will lead to reduced shame and suffering for ....Paving the way for effective public health interventions for bulimic eating disorders: Understanding stigma and mental health literacy. This research contributes to promoting and maintaining good health. The burden of bulimic eating disorders in the community is high, frequently ignored and increasing. Our research will pave the way for improved understanding of eating disorders and a reduction of stigma in relation to these problems. In so doing, it will lead to reduced shame and suffering for people with eating disorders and enhance appropriate treatment seeking and the quality of advice received from family, friends and health professionals. A public health intervention based on our findings will contribute to a more tolerant and understanding community.Read moreRead less
High Performance in Elite Sports: A Cultural History of Medicine, Psychology, and Society during the Weimar Republic and Nazism, 1918-1945. Australia has long had an excellent international reputation for innovative research on European history. This research project will expand that reputation by providing cutting-edge research into a new field that is just beginning to be developed. The project brings together research in sport with research into the history of science and medicine that will a ....High Performance in Elite Sports: A Cultural History of Medicine, Psychology, and Society during the Weimar Republic and Nazism, 1918-1945. Australia has long had an excellent international reputation for innovative research on European history. This research project will expand that reputation by providing cutting-edge research into a new field that is just beginning to be developed. The project brings together research in sport with research into the history of science and medicine that will allow Australia to participate in major international debates in all of these fields. It examines the social and cultural significance of sports using Germany as a case study. A sports conscious and performance oriented society like Australia would certainly benefit from insights about the relationship between sports and performance management in a different time and place.Read moreRead less
Investigation of the resilience of immune memory to manipulation by pathogens. Vaccines have a major impact on the wellbeing of humans as well as productivity and welfare of veterinary species and pets. New vaccines have therefore a tremendous effect on both the economy and the community. Here we investigate in how far an adjuvanted vaccine can influence the type of immune response induced during subsequent infection when the pathogen has developed mechanisms to subvert the induced protective im ....Investigation of the resilience of immune memory to manipulation by pathogens. Vaccines have a major impact on the wellbeing of humans as well as productivity and welfare of veterinary species and pets. New vaccines have therefore a tremendous effect on both the economy and the community. Here we investigate in how far an adjuvanted vaccine can influence the type of immune response induced during subsequent infection when the pathogen has developed mechanisms to subvert the induced protective immune response. This question has profound implications for all vaccine and adjuvant development activities, as the resilience of immune memory is not yet considered an important parameter in the design of adjuvants yet it is fundamental to the successful of vaccines against many pathogens.Read moreRead less
Patients' preference for participation in patient safety activities. This study will identify patient and nurse perceptions of involving patients in patient safety activities. Priorities for implementing strategies to support patient participation in patient safety activities will be identified, which will influence both health policy and practice.