A study of the archaeology of Caucasian Iberia with implications for grazing management in Australia. This multi-disciplinary project will promote a younger generation of talented postgraduate and undergraduate students in a wide variety of fields, including archaeology, geomatic engineering, conservation of material culture, environmental and other natural sciences. The highlands of the Caucasus, located in a bioclimatic zone with a long history of alpine grazing, can also provide answers to qu ....A study of the archaeology of Caucasian Iberia with implications for grazing management in Australia. This multi-disciplinary project will promote a younger generation of talented postgraduate and undergraduate students in a wide variety of fields, including archaeology, geomatic engineering, conservation of material culture, environmental and other natural sciences. The highlands of the Caucasus, located in a bioclimatic zone with a long history of alpine grazing, can also provide answers to questions such as the effect of grazing on biodiversity and the rehabilitation of fragile ecosystems, which may inform management and conservation activities in analogous highland country in Australia. The project will also ensure that exhibitions illustrating the rich heritage of Caucasus will reach Australian shores.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE140100620
Funder
Australian Research Council
Funding Amount
$395,220.00
Summary
Inference, control and protection of interdependent spatial networked structures. Networked structures are everywhere and modern societies largely depend on their proper functioning. Some of these networks are spatial with each node having a geographical tag. Examples include power grids, the internet and transportation networks. These networks are often interdependent where their functioning depends on each other. This project will establish a mathematical framework to efficiently observe and c ....Inference, control and protection of interdependent spatial networked structures. Networked structures are everywhere and modern societies largely depend on their proper functioning. Some of these networks are spatial with each node having a geographical tag. Examples include power grids, the internet and transportation networks. These networks are often interdependent where their functioning depends on each other. This project will establish a mathematical framework to efficiently observe and control interdependent spatial networks and develop design strategies in order to maximise residency of spatial networks against catastrophic failures in their components. The outcomes of the project will protect the Australian power grid and transportation networks against random and intentional failures. Read moreRead less
The Role Of Non-classical MHC Class I Molecules In Adaptive Immunity
Funder
National Health and Medical Research Council
Funding Amount
$443,834.00
Summary
Specialised proteins called MHC class Ia molecules (MHC-Ia) stimulate killer T cells to lyse virus infected cells. In contrast, the function of the closely related MHC-Ib is uncertain. Recent findings have demonstrated that MHC-Ib can also be recognised by T cells and this interaction is important in the control of viral infections. However, despite the similarity to MHC-Ia, it is unclear how this interaction occurs. This project aims to investigate how killer T cells recognise MHC-Ib molecules.
Engineering evolving complex network systems through structure intervention. This project aims to create a theory and technology for engineering complex network systems (CSS) through structural intervention. Complex network systems with evolving components are ubiquitous in nature and society. The science of biological networks, the Internet and large-scale power networks demand tools to understand and influence their evolving dynamics. This project could result in a breakthrough theory in netwo ....Engineering evolving complex network systems through structure intervention. This project aims to create a theory and technology for engineering complex network systems (CSS) through structural intervention. Complex network systems with evolving components are ubiquitous in nature and society. The science of biological networks, the Internet and large-scale power networks demand tools to understand and influence their evolving dynamics. This project could result in a breakthrough theory in network science and technology to augment biological systems and power grids. Expected benefits include cost-effective augmentation of power networks injected with renewable energy sources, and advancing basic biology research.Read moreRead less
Dhenia: A study of regionalism, population and society in Bronze Age Cyprus. The cemetery complex at Dhenia in Cyprus was in use for 2500 years, from the beginning of the Bronze Age (2,400 BCE) to the end of the Iron Age. This project is designed to sample this extensive site to assess its changing size and structure during periods of major social transformation. Comparative studies of contemporary sites will provide the basis for monitoring and explaining local, regional and island-wide relatio ....Dhenia: A study of regionalism, population and society in Bronze Age Cyprus. The cemetery complex at Dhenia in Cyprus was in use for 2500 years, from the beginning of the Bronze Age (2,400 BCE) to the end of the Iron Age. This project is designed to sample this extensive site to assess its changing size and structure during periods of major social transformation. Comparative studies of contemporary sites will provide the basis for monitoring and explaining local, regional and island-wide relationships, viewed in a context of expanding population and increasing interaction with the wider Mediterranean world. New data and approaches will contribute significantly to Cypriot archaeology and to broader archaeological theory.Read moreRead less
Structural Studies On The Immune Effector Perforin: Developing Mechanism-based Inhibitors
Funder
National Health and Medical Research Council
Funding Amount
$1,116,594.00
Summary
Perforin is an essential weapon deployed by the human immune cells in order to destroy virally infected or cancerous cells. Despite this key role, unwanted or excessive perforin function can result in disease and can severely impact on successful treatment of leukaemia through bone marrow transplantation. This application aims to understand the molecular details of perforin function, and to apply this knowledge to develop perforin inhibitors.
Discovery Early Career Researcher Award - Grant ID: DE180101268
Funder
Australian Research Council
Funding Amount
$367,446.00
Summary
Inference and resilient control of complex cyber-physical networks. This project aims to establish a fundamental framework to efficiently analyse and control critical, modern infrastructure networks such as power grids and the Internet. The project expects to bridge the gap between cyber-physical network theory and network resilience engineering through developing a body of knowledge about cyber-physical systems, security analysis and emergence of network behaviours. The project will develop des ....Inference and resilient control of complex cyber-physical networks. This project aims to establish a fundamental framework to efficiently analyse and control critical, modern infrastructure networks such as power grids and the Internet. The project expects to bridge the gap between cyber-physical network theory and network resilience engineering through developing a body of knowledge about cyber-physical systems, security analysis and emergence of network behaviours. The project will develop design methodologies to improve the resilience of these networks against internal faults and external attacks. This should improve the robustness and invulnerability of Australian power grids and the Internet against random failures and malicious cyber-physical attacks.Read moreRead less
The Unique Nature Of Gamma Delta T Cell Recognition Resolved Through Interaction With H2-Q10
Funder
National Health and Medical Research Council
Funding Amount
$699,031.00
Summary
The liver is important for both digestion and immunity. Given these opposing functions, the liver must exert control points that prevent the immune system from recognising food products. We have now identified a new molecular target that controls the development of immune cells in the liver.
In the Wake of the Sea Peoples, In the Footsteps of Goliath: Excavating the Philistine Site of Tell es-Safi/Gath. This project brings Australian research into the current scholarly debates on Philistine identity, a quickly growing sub-discipline in Mediterranean archaeology. Marginalized in the Bible as decadent, current research sees the Philistines as a cosmopolitan culture resulting from migration from Cyprus and the Aegean, and interaction with the local Canaanite population. In addition, Au ....In the Wake of the Sea Peoples, In the Footsteps of Goliath: Excavating the Philistine Site of Tell es-Safi/Gath. This project brings Australian research into the current scholarly debates on Philistine identity, a quickly growing sub-discipline in Mediterranean archaeology. Marginalized in the Bible as decadent, current research sees the Philistines as a cosmopolitan culture resulting from migration from Cyprus and the Aegean, and interaction with the local Canaanite population. In addition, Australian collaboration and interaction with Israeli colleagues and students will contribute to a more positive perception of the Jewish community in Australia, which has been the recent target of anti-Semitic activities as a result of the Israeli government's invasion of Gaza.Read moreRead less
Special Research Initiatives - Grant ID: SR0354580
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
Sustainable Futures through Understanding Past Human Responses to Environmental Change. This Network brings together researchers within archaeology and environmental sciences to develop cross-disciplinary and internationally comparative approaches to understanding past human responses to rapid environmental change. Integration of skills and perspectives from the Humanities and Sciences will create a generation of scholars able to work across different theoretical frameworks to formulate credible ....Sustainable Futures through Understanding Past Human Responses to Environmental Change. This Network brings together researchers within archaeology and environmental sciences to develop cross-disciplinary and internationally comparative approaches to understanding past human responses to rapid environmental change. Integration of skills and perspectives from the Humanities and Sciences will create a generation of scholars able to work across different theoretical frameworks to formulate credible responses to the challenge of creating sustainable societies in a changing world. Through a greater understanding of past societies' reactions to rapid environmental change, the Network will build on existing leading edge research and create a more informed guide to a sustainable future.Read moreRead less