Electrohydrodynamically-Driven Microcentrifugation for Microfluidic Applications. Microfluidics has the potential to revolutionise the way we live. Imagine portable pocket sized devices for cheap and rapid medical diagnostics and drug delivery. Or miniaturised chemical/biological sensors as early warning detection systems against terrorist threats. The research is thus intended to not only commercially benefit various industries, but also to improve the quality of life as a whole by making medic ....Electrohydrodynamically-Driven Microcentrifugation for Microfluidic Applications. Microfluidics has the potential to revolutionise the way we live. Imagine portable pocket sized devices for cheap and rapid medical diagnostics and drug delivery. Or miniaturised chemical/biological sensors as early warning detection systems against terrorist threats. The research is thus intended to not only commercially benefit various industries, but also to improve the quality of life as a whole by making medical diagnosis or chemical/biological detection more readily accessible, portable and more efficient. Moreover, the fundamental studies, aimed at generating an understanding of the complex physics involved, has generic benefits to researchers in applied physics as well as providing practical protocols for microdevice development.Read moreRead less
Design of granule microstructure in fluidised bed granulation: Modelling & experimental realisation. Production of granules with engineered microstructure is a common industrial problem. This project focuses on understanding how to control the microstructure of granules - including size, porosity, composition - produced by fluidised bed granulation by developing systematic, science based design rules. Designer granules can be used to develop and fast-track the development of innovative microstru ....Design of granule microstructure in fluidised bed granulation: Modelling & experimental realisation. Production of granules with engineered microstructure is a common industrial problem. This project focuses on understanding how to control the microstructure of granules - including size, porosity, composition - produced by fluidised bed granulation by developing systematic, science based design rules. Designer granules can be used to develop and fast-track the development of innovative microstructured products for niche markets and the next generation of high-value agricultural, food and pharmaceutical industries. This unique project clearly contributes to the National Research Priority of 'Frontier Technologies' and will further enhance Australia's world-class excellence in both powder fluidisation and granulation research.Read moreRead less
Modern Low Oxidation State/Low Coordination Main Group Chemistry: A New Domain for Australian Science. The proposed research will benefit Australia by creating a knowledge base in an internationally important area of chemistry. This will be aided by the return to Australia of an international leader in the field. Through an integrated and interdisciplinary approach, the exploitation of technologies arising from the research program will be explored. In addition to the academic community, these ....Modern Low Oxidation State/Low Coordination Main Group Chemistry: A New Domain for Australian Science. The proposed research will benefit Australia by creating a knowledge base in an internationally important area of chemistry. This will be aided by the return to Australia of an international leader in the field. Through an integrated and interdisciplinary approach, the exploitation of technologies arising from the research program will be explored. In addition to the academic community, these technologies will benefit hi-tech industries including pharmaceutical and fine chemicals concerns which will gain from the use of the proposed group 13 heterocycles in organic synthesis. Moreover, industries reliant on polymer supports in catalytic process or opto-electronic polymers will profit from the various polymers derived from phosphaalkynes.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0346870
Funder
Australian Research Council
Funding Amount
$290,000.00
Summary
High framing rate stereoscopic particle image velocimetry (HFR SPIV) facility. This proposal seeks to establish a specialised high framing rate stereoscopic particle image velocimetry (HFR SPIV) facility for the measurement of rapidly changing velocity fields in complex flows. The proposed facility is currently not available in Australia and is significant in that it provides a continuous time sequence of rapidly changing 3D velocity fields in a two-dimensional plane. The facility will provide e ....High framing rate stereoscopic particle image velocimetry (HFR SPIV) facility. This proposal seeks to establish a specialised high framing rate stereoscopic particle image velocimetry (HFR SPIV) facility for the measurement of rapidly changing velocity fields in complex flows. The proposed facility is currently not available in Australia and is significant in that it provides a continuous time sequence of rapidly changing 3D velocity fields in a two-dimensional plane. The facility will provide experimental validation for models and theories developed for fast transient flows in non-periodic time dependent flows, multi-phase flows, solid mechanics and natural convection.Read moreRead less
Why is the photosynthetic CO2-fixing enzyme, Rubisco, so inefficient? Dissection of the catalytic chemistry by computational simulation and experimental testing. Fixation of CO2 by the enzyme Rubisco during photosynthesis produces organic compounds which feed all life. Despite this critical role, Rubisco catalyses its reaction sluggishly and, worse, discriminates poorly between CO2 and O2, leading to useless products. Our combined expertise equips us to analyse Rubisco's mechanism using quantum- ....Why is the photosynthetic CO2-fixing enzyme, Rubisco, so inefficient? Dissection of the catalytic chemistry by computational simulation and experimental testing. Fixation of CO2 by the enzyme Rubisco during photosynthesis produces organic compounds which feed all life. Despite this critical role, Rubisco catalyses its reaction sluggishly and, worse, discriminates poorly between CO2 and O2, leading to useless products. Our combined expertise equips us to analyse Rubisco's mechanism using quantum-chemical methods and then test predictions experimentally. We will capitalise on our previous successful studies of Rubisco by addressing emergent issues which are the keys to understanding catalytic efficiency and CO2/O2 selectivity: the roles of a carbamylated lysine; the way CO2 addition is rendered irreversible; and the spin inversion inherent in O2 addition.Read moreRead less