Cellular mechanisms that protect against copper-bound beta-amyloid. This project will investigate some of the brain’s own mechanisms for protecting itself against Alzheimer’s disease. Understanding these mechanisms will be important for developing future therapeutic strategies for treating Alzheimer’s disease.
Study of molecular interactions between wood pitch fixatives and components of wood pitch. Wood resins, released in pulping, agglomerate in the papermaking process to cause pitch deposits. These deposits adversely affect paper machine efficiency and product quality and limit further recycling of process water. This project aims to investigate the interactions between the components of the wood resins and different fixatives using capillary electrophoresis and other techniques. This knowledge w ....Study of molecular interactions between wood pitch fixatives and components of wood pitch. Wood resins, released in pulping, agglomerate in the papermaking process to cause pitch deposits. These deposits adversely affect paper machine efficiency and product quality and limit further recycling of process water. This project aims to investigate the interactions between the components of the wood resins and different fixatives using capillary electrophoresis and other techniques. This knowledge will provide a better understanding of the role of the physical and chemical properties of the fixatives in fixing the different compounds in wood resins. Molecular modelling will be used to design new fixatives that will be selective to a mixture of wood resins.
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Reduced water usage in the Australian pulp and paper industry through novel process chemistry. Norske Skog Paper Mill operates two paper mills on major rivers in Australia. For these mills to reduce water consumption greater recycling of the process water is needed which results in a build-up of detrimental substances that will affect paper machine performance and efficiency. The knowledge gained from this project will help the paper mills to find strategies to control the build-up of the detr ....Reduced water usage in the Australian pulp and paper industry through novel process chemistry. Norske Skog Paper Mill operates two paper mills on major rivers in Australia. For these mills to reduce water consumption greater recycling of the process water is needed which results in a build-up of detrimental substances that will affect paper machine performance and efficiency. The knowledge gained from this project will help the paper mills to find strategies to control the build-up of the detrimental material and deal with it in such a way that the process water can be recycled and the paper mills can reduce water consumption.Read moreRead less
Criminalisation of poverty and homelessness in Australia: A national study. The project aims to assess the policing and enforcement of public order crimes and related offences (e.g. obstruct/disobey police, breach of bail, and minor property offences) on individuals experiencing poverty and homelessness. The project endeavours to collect and analyse qualitative data from across Australia on the lived experience of people who are homeless or at risk of homelessness, regarding the impact of crimin ....Criminalisation of poverty and homelessness in Australia: A national study. The project aims to assess the policing and enforcement of public order crimes and related offences (e.g. obstruct/disobey police, breach of bail, and minor property offences) on individuals experiencing poverty and homelessness. The project endeavours to collect and analyse qualitative data from across Australia on the lived experience of people who are homeless or at risk of homelessness, regarding the impact of criminal laws and police powers concerned with presence in, and movement around public places. It will particularly focus on the impact on women, children and Indigenous peoples. The outcomes will seek to reduce the criminalisation of homeless people, by identifying law and policy reform options, and comparing their cost with that of 'business as usual'.Read moreRead less
Colloid interactions and extraction in sustainable, water efficient paper manufacture. This project will investigate the causes of wood extractive deposits on modern high-speed printing surfaces. The project will also develop alternatives to prevent their deposition in an environmentally sustainable manner, and to remove them from the paper making process allowing their utilisation as valuable natural products.
Redefining the metallothionein's role in the injured brain: extracellular metallothioneins play an important role in astrocyte-neuron responses to injury. This project is being performed by an Australian team of researchers who are leaders in this field of research, and has significant national benefits in supporting this team reveal fundamental information on the cellular interactions that occur between astrocytes and neurons within the injured brain. In national terms, it will contribute to th ....Redefining the metallothionein's role in the injured brain: extracellular metallothioneins play an important role in astrocyte-neuron responses to injury. This project is being performed by an Australian team of researchers who are leaders in this field of research, and has significant national benefits in supporting this team reveal fundamental information on the cellular interactions that occur between astrocytes and neurons within the injured brain. In national terms, it will contribute to the concerted effort by Australian scientists to understand how and why neurons die following brain injury or neurodegenerative disease. Furthermore, this research contributes directly to the Designated National Research Priorities by identifying some of the earliest biochemical and cellular processes associated with aging or disease of the brain.Read moreRead less
Improved management of coastal plankton systems by ancient DNA technology. This project aims to assemble comprehensive long term Australian plankton records spanning 50 to 1000 years, by applying ancient DNA technology to dated sediment depth cores. Long-term data for Australian coastal and estuarine waters are sparse, so cannot be used for management of fisheries, tourism or urban development. Long-term records are essential to understand how disruptive algal and jellyfish blooms, introduced sp ....Improved management of coastal plankton systems by ancient DNA technology. This project aims to assemble comprehensive long term Australian plankton records spanning 50 to 1000 years, by applying ancient DNA technology to dated sediment depth cores. Long-term data for Australian coastal and estuarine waters are sparse, so cannot be used for management of fisheries, tourism or urban development. Long-term records are essential to understand how disruptive algal and jellyfish blooms, introduced species and increased human use of coastal resources affect dynamic plankton ecosystems. This project’s findings are expected to explore cyclical patterns, define range expansions and understand and manage how dynamic coastal ecosystems respond to multistressor anthropogenic change. Findings will improve understanding of how dynamic marine environments retain their biodiversity values and critical ecological functions.Read moreRead less
Effect of climate boundary changes on the Southern Westerly Winds. This project aims to produce high quality data on how the Southern Westerly Winds (SWW) respond to largescale changes in climate boundary conditions over multiple glacial-interglacial cycles. Because the SWW are key drivers of Southern Hemisphere climate, Southern Ocean circulation and global carbon dioxide concentrations, it is important to understand how they respond to changes in boundary conditions. Uncertainty about how they ....Effect of climate boundary changes on the Southern Westerly Winds. This project aims to produce high quality data on how the Southern Westerly Winds (SWW) respond to largescale changes in climate boundary conditions over multiple glacial-interglacial cycles. Because the SWW are key drivers of Southern Hemisphere climate, Southern Ocean circulation and global carbon dioxide concentrations, it is important to understand how they respond to changes in boundary conditions. Uncertainty about how they do so limits attempts at accurate predictive climate modelling. This project will test conceptual models of SWW dynamics and provide essential boundary conditions for predictive climate models. The project intends to simultaneously build and support a research capacity and global network, and advance Australia’s knowledge and contribution in the area of global climate dynamics.Read moreRead less
The impact of environmental change on larval energetics of molluscs on the southeast coast of Australia. This project will investigate the impact of environmental change on larval energetics of molluscs on the southeast (SE) coast of Australia. The SE coast of Australia is a climate hotspot characterised by rising ocean temperatures, fluctuations in salinity and we expect in the near future ocean acidification (OA). Mollusc larvae show extreme sensitivity to OA, but the impacts of other stressor ....The impact of environmental change on larval energetics of molluscs on the southeast coast of Australia. This project will investigate the impact of environmental change on larval energetics of molluscs on the southeast (SE) coast of Australia. The SE coast of Australia is a climate hotspot characterised by rising ocean temperatures, fluctuations in salinity and we expect in the near future ocean acidification (OA). Mollusc larvae show extreme sensitivity to OA, but the impacts of other stressors remains unknown. It is predicted that OA will reduce the capacity of larvae to cope with temperature and salinity, particularly when food supply is low and in populations which have had no previous exposure to OA. Understanding the response of mollusc larvae to environmental change will support ecologically and economically significant mollusc populations over this century.Read moreRead less
The last glaciation maximum climate conundrum and environmental responses of the Australian continent to altered climate states. This project will show how climate systems in south east Australia responded to large scale global change the last time this happened, which was about 21,000 years ago. By determining the climate response in Australia to this change, this project will help predict future response in rainfall and temperature to human-induced and natural climate change.