Child Disability:understanding Determinants And Improving Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$697,605.00
Summary
The overall goals of my research are: to learn more about the causes of developmental disorders so that we can either prevent them occurring, or develop effective treatments for them; to improve the understanding, diagnosis and management of rare genetic disorders by developing and maintaining registers and by collaborating internationally; and to investigate the impact of rare and common developmental disorders on the health and quality of life of the affected child and their family.
Increasing Value, Reducing Waste From Incomplete Or Unusable Reports Of Medical Research
Funder
National Health and Medical Research Council
Funding Amount
$788,486.00
Summary
We estimated that the avoidable waste in research - from design flaws, non-publication, and inadequate reporting - results in over $85 Billion annual loss. I will research innovations to reduce this waste. My focus is particularly on non-drug interventions - exercises, dietary changes, self-monitoring, e-health applications – which are often effective but more difficult to use in clinical practice, and being compiled in my recently founded Handbook of Non-Drug Interventions (see RACGP website).
The aim of this research project is to provide critical new information on the functional changes in brain circuits mediating cognitive-emotional integration during decision-making. This project will use a powerful and unique combination of behavioural, circuit-level, cellular, genetic and imagining tools to assess decision processes in healthy rodent and human subjects, and in animal models of, and humans suffering from, specific psychiatric disorders.
Using Healthcare Wisely: Psychosocial Interventions To Reduce Unnecessary Testing And Treatment
Funder
National Health and Medical Research Council
Funding Amount
$763,845.00
Summary
Overuse of healthcare (use of unnecessary tests and treatments) is harming patients and diverting scarce health resources from where they are most needed. Effective communication of the problem to the public, patients, clinicians and policymakers is a prerequisite for behaviour change. This fellowship will develop a suite of communication-based interventions to reduce overuse and build a multidisciplinary workforce of researchers to address this urgent problem facing health systems globally.
Building Capacity For Health Services Research In Australia
Funder
National Health and Medical Research Council
Funding Amount
$697,209.00
Summary
I have developed a programme of applied health services research by winning grants, publications in good journals, investing in PhD and post-doc researchers and engaging with state governments and health departments. In 2011 I set up the Australian Centre for Health Services Innovation that will improve health services by funding health services research, and offering research training for health care professionals. The purpose of this fellowship is to sustain this activity.
New Interventions To End Neglected Tropical Diseases In Asia
Funder
National Health and Medical Research Council
Funding Amount
$926,980.00
Summary
My research goal is to eliminate parasitic worm infestations globally. These parasites cause substantial illness and affect the world's poorest people. Programs that drug treat infected individuals operate but these are neither effective nor sustainable. Our research has shown that additional measures, such as vaccination and health education, are needed and we aim to develop and field test a combination of interventions that will lead to their sustainable control and eventual elimination.
Delivering Quality Maternal And Newborn Care: Translating ‘evidence-based Practice’ Into ‘every-day Practice’
Funder
National Health and Medical Research Council
Funding Amount
$849,540.00
Summary
More than 300,000 women each year in Australia use maternity services. Unfortunately these are not always based on the best available evidence and there are considerable variations across the country. This research will provide much needed information to ensure that all women receive evidence-based care not just some women. The research will be initially conducted in south western Sydney but will ultimately improve the quality of care offered to women and babies across the country and beyond.
Innovative School-based Interventions To Improve Mental Health And The Social And Emotional Development Of Australian Children
Funder
National Health and Medical Research Council
Funding Amount
$763,845.00
Summary
I am a Professor in the Faculty of Medicine, Dentistry and Health Sciences, University of Western Australia and the Telethon Kids Institute. My research develops and delivers interventions that improve the quality of life, health, education, safety and social justice outcomes for Australian children. My work is particularly focused on ways to reduce harms from bullying and cyberbullying among children and adolescents.
A common characteristic of cancer is the failure of cells to die when they normally would. One of the problems with many cancer therapies is that they rely on the integrity of signalling pathways to the normal ‘death machinery’ of the cell to do their job. By understanding how the molecular death machine operates we are fashioning new drugs that can target it directly, thus bypassing the very pathways that are so frequently disrupted in tumour cells.
Innovations In Prevention And Treatment Of Vascular Disease
Funder
National Health and Medical Research Council
Funding Amount
$876,005.00
Summary
Novel clinical trials and related basic science research in the prevention and treatment of heart and blood vessel disease and diabetic complications will be undertaken, building on extensive collaborations and novel discoveries to date.