Assembly of neural circuits during development. This program aims to understand how nerve cells wire up accurately during development. Specifically, the program will determine how neuronal connections are established in the retina to produce a sensory structure essential for vision. The program will also generate innovative tools for watching in live animals, the making and breaking of connections during normal and abnormal development. Discoveries will not only significantly increase our knowle ....Assembly of neural circuits during development. This program aims to understand how nerve cells wire up accurately during development. Specifically, the program will determine how neuronal connections are established in the retina to produce a sensory structure essential for vision. The program will also generate innovative tools for watching in live animals, the making and breaking of connections during normal and abnormal development. Discoveries will not only significantly increase our knowledge base of how the nervous system develops or degenerates, but the results will provide crucial information for future studies based on genetic approaches, drug therapies and bioengineering technology to repair the injured nervous system.Read moreRead less
Neural mechanisms of attention in the honeybee and Drosophila melanogaster. By examining convergent neural mechanisms of attention in insects and comparing these mechanisms to those found in vertebrates, we may uncover basic principles of how attention operates in widely divergent systems. This type of basic scientific research could be used to provide a framework to develop better approaches for treatment for individuals with defects in attention. Such defects are symptoms of several psycholo ....Neural mechanisms of attention in the honeybee and Drosophila melanogaster. By examining convergent neural mechanisms of attention in insects and comparing these mechanisms to those found in vertebrates, we may uncover basic principles of how attention operates in widely divergent systems. This type of basic scientific research could be used to provide a framework to develop better approaches for treatment for individuals with defects in attention. Such defects are symptoms of several psychological conditions, including attention deficit disorder, autism, and schizophrenia, which have major social and economic costs in Australia. Therefore, by expanding our understanding of how attention operates at the level of neurons, we can begin to develop targeted treatments for addressing these conditions. Read moreRead less
Processing of social communication calls in primate auditory cortex. This research will advance our understanding of the brain mechanisms involved in perception of sound. This will help to understand disorders of speech and hearing following brain damage and may assist in efforts to develop better hearing aids, as well as other speech recognition technologies. In addition, we will develop a primate for studying processing of sound in the brain that will be useful in future research to develop ....Processing of social communication calls in primate auditory cortex. This research will advance our understanding of the brain mechanisms involved in perception of sound. This will help to understand disorders of speech and hearing following brain damage and may assist in efforts to develop better hearing aids, as well as other speech recognition technologies. In addition, we will develop a primate for studying processing of sound in the brain that will be useful in future research to develop improved cochlear implants.Read moreRead less
How the brain produces speech. Speech production is a fundamental ability that enables human interaction through language. Brain injuries impair this ability, with profound negative consequences for the individual and their immediate family and friends. This project will increase our understanding of the brain mechanisms involved in producing speech by using state-of-the-art brain imaging techniques. The findings will inform future clinical research and improve the advice given to clinicians, pa ....How the brain produces speech. Speech production is a fundamental ability that enables human interaction through language. Brain injuries impair this ability, with profound negative consequences for the individual and their immediate family and friends. This project will increase our understanding of the brain mechanisms involved in producing speech by using state-of-the-art brain imaging techniques. The findings will inform future clinical research and improve the advice given to clinicians, patients and the broader community about the nature of language production and its impairments and ultimately the treatment of speech disorders.Read moreRead less
Dynamics of Locomotion: Visualisation in skill acquisition & rehabilitation. How does visual information and attention determine the control and coordination of locomotion? Using large-screen projection of computer graphics and immersive virtual reality, we will examine the influence of visual information on driver training, gait in the elderly, cardiorespiratory control, and the attentional interference of mobile phones on driving. Experiments will be based on principles from dynamical and comp ....Dynamics of Locomotion: Visualisation in skill acquisition & rehabilitation. How does visual information and attention determine the control and coordination of locomotion? Using large-screen projection of computer graphics and immersive virtual reality, we will examine the influence of visual information on driver training, gait in the elderly, cardiorespiratory control, and the attentional interference of mobile phones on driving. Experiments will be based on principles from dynamical and complex systems theory and will inform the design of innovative algorithms for autonomous mobile robots. Expected outcomes include improved road safety, new methods for the rehabilitation of those with gait disorders, and a deeper understanding of the physiological response to virtual exercise.Read moreRead less
Audio-visual Information for Speech-hand Gestures. How does audio-visual information influence human movement and communication? We will investigate whether speech and hand gestures involve shared information about the timing of rhythmic movements. Using dynamical systems theory and brain imaging techniques, we will study rhythms that emerge during simultaneous speaking and finger tapping in both stutterers and non-stutterers, and in left-handers and right-handers. The communicative interaction ....Audio-visual Information for Speech-hand Gestures. How does audio-visual information influence human movement and communication? We will investigate whether speech and hand gestures involve shared information about the timing of rhythmic movements. Using dynamical systems theory and brain imaging techniques, we will study rhythms that emerge during simultaneous speaking and finger tapping in both stutterers and non-stutterers, and in left-handers and right-handers. The communicative interaction of two persons performing speech-hand gestures will be examined. Results will clarify how brain asymmetry affects gestural coordination in stutterers, how stuttering can be treated, and the hypothesis that speech and language evolved from a communication system based on hand gestures.
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