Better Evidence And New Tools To Improve Health After Surgical Menopause
Funder
National Health and Medical Research Council
Funding Amount
$1,855,260.00
Summary
Surgical menopause is removal of both ovaries before natural menopause. Surgical menopause may have severe adverse health consequences including short-term symptoms and long-term risk of chronic disease, but more information is needed to inform evidence-based care. This study will deliver the best available evidence internationally on the short (up to 5 year) and long (>20 year) consequences of surgical menopause and new tools for clinicians and patients to integrate this evidence into practi ....Surgical menopause is removal of both ovaries before natural menopause. Surgical menopause may have severe adverse health consequences including short-term symptoms and long-term risk of chronic disease, but more information is needed to inform evidence-based care. This study will deliver the best available evidence internationally on the short (up to 5 year) and long (>20 year) consequences of surgical menopause and new tools for clinicians and patients to integrate this evidence into practiceRead moreRead less
Nutritional Psychiatry: Extending The Evidence And Ensuring Translation
Funder
National Health and Medical Research Council
Funding Amount
$2,238,220.00
Summary
While poor diet is the leading contributor to illness and premature death globally, mental disorders account for the leading cause of disability. I have led the field internationally in establishing, for the first time, that diet quality and mental health are linked and have established a new field of research and clinical practice ‘Nutritional Psychiatry’. My program of research will now extend the evidence base and facilitate translation of this new knowledge into policy and practice.
Improving Patient Outcomes In Familial Hypercholesterolaemia Across The Continuum Of Care
Funder
National Health and Medical Research Council
Funding Amount
$645,205.00
Summary
'Familial' means it runs in families and 'hypercholesterolaemia' means high blood cholesterol. Familial Hypercholesterolaemia (FH) is the most common and serious form of inherited high cholesterol. People with FH are at an increased risk of developing cardiovascular disease. High cholesterol also placed an estimated $4 billion burden on the Australian economy in 2017-18. Practical research on prevention strategies will improve cardiovascular health outcomes and lower the burden of health costs.
Blocking Paths To Suicide: A Data Linkage Program To Identify Modifiable Risk Factors For Self-poisoning And Suicide In Australia
Funder
National Health and Medical Research Council
Funding Amount
$501,205.00
Summary
This research examines the relationship between medicines use and suicide. Some medicines may be more toxic than others and identification of these could allow for targeted restrictions. In addition, medication use practices may influence self-harm and suicide. This research will identify patterns (e.g. non-adherence prior to death, incorrect doses) to pinpoint beneficial or harmful practices. This will improve outcomes and help guide suicide prevention through targeted legislation and policy.
Unified Prevention Of Substance Use And Mental Disorders.
Funder
National Health and Medical Research Council
Funding Amount
$2,560,520.00
Summary
Substance use and mental disorders are among the leading causes of burden of disease in young people globally. Yet prevention and early intervention has not been prioritised in Australian research and policy.The major focus of my research will be on examining the effectiveness of new unified prevention programs.
INFORM-AF A Randomised Controlled Trial To Assess The Efficacy Of A Digital Education Program For Atrial Fibrillation
Funder
National Health and Medical Research Council
Funding Amount
$606,009.00
Summary
This grant aims to evaluate a new digital education program to improve quality of life for people living with atrial fibrillation and reduce rehospiatlisations.
Healthy Lungs For Life: A Life Course Approach To Reduce COPD
Funder
National Health and Medical Research Council
Funding Amount
$2,491,398.00
Summary
Chronic Obstructive Lung Disease (COPD) causes breathing distress, disability and premature death. I have shown that COPD mostly has its origins in childhood. This means we can now identify early life risk factors to prevent COPD or help us catch it early, to improve health. My 5-year vision is to reduce the dire burden of COPD by creating evidence to change guidelines and policy and facilitating the transfer of that knowledge to practice.
Reducing Colorectal Cancer Burden In Young Adults: Precision Prevention And Early Detection
Funder
National Health and Medical Research Council
Funding Amount
$1,449,800.00
Summary
Bowel cancer rate in young adults before age 50 is increasing worldwide including Australia. Since it is impossible to screen everyone, it is critical to identify who is likely to develop the disease, to optimise screening. Using the world's largest resource for young-onset bowel cancer, I will conduct studies to generate high-quality evidence to inform how to best prevent bowel cancer in young adults and translate into the policy and practice, to reduce colorectal cancer burden in young adults.
Improving Outcomes For Children With Cancer: Targeted Treatments And Prevention
Funder
National Health and Medical Research Council
Funding Amount
$900,000.00
Summary
Child cancer is the commonest disease causing death in children. Relapse is due to small, treatment-resistant populations of cancer cells in the initial tumour. Improvements in cure rates have slowed due to poor investment by the pharmaceutical industry in targeting specific child cancer driver genes. My program of research will use novel technologies to identify: new vulnerabilities for combination drug therapies, drugs directed against child cancer gene targets and strategies for prevention.
Breast Arterial Calcification And Cardiovascular Disease – Exploring Mechanisms And Outcomes.
Funder
National Health and Medical Research Council
Funding Amount
$645,205.00
Summary
Heart disease remains the major of cause of death in women in the Western world and current methods of screening women for heart disease are out-dated and inaccurate. Calcification in the breast arteries that can be diagnosed on screening mammograms has been associated with future heart disease. This may represent a unique way to screen and treat patients for heart disease without the need for additional testing and our research program aims to investigate this.