Morbidity, Mortality And Health Service Use Among Criminal Offenders: A Western Australian Population-based Study
Funder
National Health and Medical Research Council
Funding Amount
$133,750.00
Summary
This study will focus on the health of criminal offenders, as a most likely marginalised and neglected section of the community, in order to identify areas of need that if addressed will possess benefits for both offenders and the general community. A research team will apply their public health, criminology and forensic psychology expertise, in partnership with the WA Police Service, to provide information on the health outcomes and health service use of adult offenders in WA. Four themes will ....This study will focus on the health of criminal offenders, as a most likely marginalised and neglected section of the community, in order to identify areas of need that if addressed will possess benefits for both offenders and the general community. A research team will apply their public health, criminology and forensic psychology expertise, in partnership with the WA Police Service, to provide information on the health outcomes and health service use of adult offenders in WA. Four themes will be explored: (1) Health Status, to estimate the prevalence of overall and cause-specific hospital-treated morbidity (2) Mortality, to estimate the prevalence of overall and cause-specific mortality, (3) Health Service Use, focussing on both the rate of primary and secondary health service use; and (4) Inequalities In Health Outcomes, firstly comparing the health outcomes of adult offenders with the general WA population, and secondly, comparing the health outcomes of adult offenders based on sanction severity and custodial setting. This investigation is one of only a few worldwide to study health among criminal offenders. Offenders are a neglected section of the Australian health system. Responding to their needs is not possible without an understanding of their health outcomes and the disparities that exist. An important public health opportunity therefore exists to investigate the health of this socially disadvantaged group. This study will provide more detailed data regarding offender-health than currently exists internationally or nationally. Results can be used by health and-or justice administrators as indicators of program and service performance, and potentially lead to improved collaboration between these sectors. The methods used for outcome evaluation can be used readily for the routine evaluation of health performance indicators for offenders.Read moreRead less
Relaxin-3 Systems In Brain: Neurophysiology And Behaviour
Funder
National Health and Medical Research Council
Funding Amount
$287,321.00
Summary
The project aim is to better understand the function of a newly-discovered signalling molecule in the mammalian brain, know as relaxin-3. Recent research suggests that this chemical is vital for normal animal behaviour, such as arousal, stress, and learning and memory processes. This project will thoroughly characterise how this chemical modulates activity of brain regions that subserve behaviour in rats. This should reveal clinical implications of relaxin-3 in human behavioural disorders.
Drinking Patterns, Gender And Social Roles In Alcohol Problems In Victoria, In An International Comparative Context
Funder
National Health and Medical Research Council
Funding Amount
$342,239.00
Summary
The varied impacts of drinking in the family and other gendered relations are an important and understudied aspect of alcohol studies, with general social and policy implications. The proposed research will make an important contribution to developing quantitative research in this area in Australia. The project uses concepts and measures which are novel in an Australian environment, and the international comparative aspect of the project, with comparable questionnaires in a wide diversity of soc ....The varied impacts of drinking in the family and other gendered relations are an important and understudied aspect of alcohol studies, with general social and policy implications. The proposed research will make an important contribution to developing quantitative research in this area in Australia. The project uses concepts and measures which are novel in an Australian environment, and the international comparative aspect of the project, with comparable questionnaires in a wide diversity of societies, is novel and innovative for the alcohol research field in general. Measures of social problems from drinking, and particularly and family and relationship, developed in analysing the study material will be made more broadly available for use in future studies, raising the possibility that the study may serve as a first measurement point for future data-series over time.Read moreRead less
Proteases, Their Inhibitors And Receptors In Degenerative Disease
Funder
National Health and Medical Research Council
Funding Amount
$5,843,388.00
Summary
Many of the themes of this program are aimed at understanding the molecular basis of several important degenerative diseases that in particular affect the ageing population. These include osteoporosis, arthritis, periodontal disease, wasting diseases of muscle and inherited disorders such as antitrypsin deficiency. The five CI’s on this application have formed a collaborative network since 1996. Dr Whisstock is a bioinformatician and structural biologist with a research focus on the serpin super ....Many of the themes of this program are aimed at understanding the molecular basis of several important degenerative diseases that in particular affect the ageing population. These include osteoporosis, arthritis, periodontal disease, wasting diseases of muscle and inherited disorders such as antitrypsin deficiency. The five CI’s on this application have formed a collaborative network since 1996. Dr Whisstock is a bioinformatician and structural biologist with a research focus on the serpin superfamily of protease inhibitors and their protease partners. He is currently the scientific director of the Victorian Bioinformatics Consortium and an NHMRC Senior Research Fellow. Dr Bird is an NHMRC Senior Research Fellow who discovered the intracellular branch of the serpin superfamily and formulated the hypothesis that describes their function. A-Prof Mackie is a world expert in the field of musculoskeletal biology and pathology. Dr Bottomley is a Senior Logan Fellow and RD Wright Fellow whose research focuses upon how proteins misfold and lead to disease. Dr Pike is an enzymologist whose research area encompasses a wide range of bacterial and mammalian proteases involved in the pathology of human disease. Each individual in this team brings different skills which makes this a very important and powerful collaboration. The research is extensive and involves protein folding, enzyme kinetics, molecular modelling, structural biology, bioinformatics, cell biology and pathology, enzyme kinetics and drug design. Collectively the CI’s have a total of 154 papers since 1998, of which a third include two or more of the CI’s as co-authors. Currently the team holds over >$5 million in grant funding. The team is augmented by four P.I.s: Dr Buckle is a talented structural biologist; Dr Scott is a molecular cell biologist who holds an NHMRC CJ Martin Fellow; Dr Garcia de la Banda is a computer scientist based at Monash and Dr Grigoryev is a world expert in chromatin condensation based at Penn State University (USA).Read moreRead less
A Comparison Of Loaded And Unloaded Exercise For People With Non-specific Chronic Low Back Pain (NSCLBP)
Funder
National Health and Medical Research Council
Funding Amount
$42,410.00
Summary
Chronic low back pain is a common and costly condition. This research will conduct studies to determine the important ingredients of exercise programs that are related to successful outcomes for people with chronic low back pain (CLBP) and also to determine the effects of an exercise program intended to strengthen or load the low back muscles and a program that encourages movement restoration through movement not intended to strengthen for people with non-specific CLBP.