Centre Of Research Excellence In Medicines Intelligence
Funder
National Health and Medical Research Council
Funding Amount
$2,500,000.00
Summary
The NHMRC Centre of Research Excellence in Medicines Intelligence is a co-ordinated research program that will accelerate the development and translation of evidence on prescribed medicines use and outcomes for regulators and payers. The CRE is perfectly placed to embrace the national ‘call to action’ from the Health Minister's recent announcement to establish Quality Use of Medicine Safety as a National Health Priority.
Developing Salient Messages For Indigenous Tobacco Control In Rural Aboriginal Smokers
Funder
National Health and Medical Research Council
Funding Amount
$117,331.00
Summary
I am a General Practitioner with a keen interest in smoking cessation particularly for Aboriginal people, who have a high rate of smoking. Media messages are not to date being completely effective in this group, so I am investigating how to make more relevant and persuasive messages to support Indigenous smokers and their families (importantly pregnant smokers) to become smoke-free and encourage them to use effective treatments to do so.
Dementia, moral agency and identity. The project aims to examine the ethical issues raised by dementia and the care of those with the condition. The project will examine and evaluate the capacities those with dementia retain for social agency, valuing and relationships. The project will test and refine theories of agency, identity and vulnerability in the light of the cognitive deficits accompanying dementia. The project will lead to the delivery of more efficient healthcare through the developm ....Dementia, moral agency and identity. The project aims to examine the ethical issues raised by dementia and the care of those with the condition. The project will examine and evaluate the capacities those with dementia retain for social agency, valuing and relationships. The project will test and refine theories of agency, identity and vulnerability in the light of the cognitive deficits accompanying dementia. The project will lead to the delivery of more efficient healthcare through the development of increased understandings of the relevant ethical considerations for treatment, and recommendations for new and ethical approaches to policy on dementia. It brings benefits to the well-being and relationships of those with this condition, their families and friends, and the professionals who care for them.Read moreRead less
Trust in a social and digital world. This project aims to provide a systematic and empirically-informed account of the way networks facilitate or hinder knowledge. Distinguishing on-line information from disinformation can be difficult. This task can be greatly assisted by networks of trusted peers, but figuring out who to trust is itself a challenge. Identifying, designing, and facilitating networks of trust is therefore an urgent task. By using the tools of social epistemology, virtue epistemo ....Trust in a social and digital world. This project aims to provide a systematic and empirically-informed account of the way networks facilitate or hinder knowledge. Distinguishing on-line information from disinformation can be difficult. This task can be greatly assisted by networks of trusted peers, but figuring out who to trust is itself a challenge. Identifying, designing, and facilitating networks of trust is therefore an urgent task. By using the tools of social epistemology, virtue epistemology, and network science, this project will identify how individuals should distribute their trust when embedded in epistemically hostile environments.Read moreRead less
Pharmacology Of Potential Anti-Tumour Agents: Iron Chelators Of The BpT Class
Funder
National Health and Medical Research Council
Funding Amount
$585,455.00
Summary
Pharmacology of Potential Anti-Tumour Agents: Iron Chelators of the BpT Class Cancer cells have a high iron requirement for DNA synthesis and many clinical trials showed Fe chelators are effective anti-cancer drugs. Their potential to act as anti-tumour agents has been confirmed by the entrance of Triapine into widespread NCI clinical trials. In this NHMRC Renewal, we will perform pharmacological and preclinical studies to promote the development of BpT chelators as novel anti-tumour agents.
Re-EValuating The Inhibition Of Stress Erosions (REVISE): Gastrointestinal Bleeding Prophylaxis In ICU
Funder
National Health and Medical Research Council
Funding Amount
$2,955,164.00
Summary
Around 50,000 patients in Australian Intensive Care Units receive a drug called pantoprazole each year with the aim of preventing bleeding from the gut. Recent research suggests this practice is ineffective and may harm patients by increasing their risk of serious infections. We will perform a definitive study to determine whether the widespread use of pantoprazole is beneficial or harmful.