Incidence And Risk Factors For Cancer After Liver And Cardiothoracic Transplantation
Funder
National Health and Medical Research Council
Funding Amount
$301,220.00
Summary
We will examine the incidence of cancer in patients before and after heart, lung, and liver transplantation. We will also examine the risk factors for cancer in these populations, including viral infection, time since transplantation, and the cause of organ failure. We will do this by linking data held by world-class Australian transplantation registries and the national cancer registry. Comparisons with other immune-deficient populations will allow valuable insight into the causes of cancer.
Cancer Incidence In Recipients Of Haematopoietic Stem Cell Transplantation In Australia
Funder
National Health and Medical Research Council
Funding Amount
$408,788.00
Summary
Haematopoietic stem cell transplantation (HSCT) is widely used in Australia to treat patients with haematological cancers. The risk of developing second malignancies after HSCT has been increasingly recognised over recent decades as more and more patients survive. The proposed study will characterise the incidence and risk factors for cancer following HSCT. This information is essential for long-term surveillance and intervention strategies in both specialist and primary care settings.
The starting point for this project is the recent finding that women who experience miscarriages or terminations of pregnancy before theuir first birth have an increased risk of having a preterm (premature) infant. These findings have prompted a re-evaluation of the relationship between the number of pregnancies a women has had and the likely outcome in later pregnancies. It will take into account the stage at which prior pregnancies ended, what the outcomes of the pregnancies were (birth, healt ....The starting point for this project is the recent finding that women who experience miscarriages or terminations of pregnancy before theuir first birth have an increased risk of having a preterm (premature) infant. These findings have prompted a re-evaluation of the relationship between the number of pregnancies a women has had and the likely outcome in later pregnancies. It will take into account the stage at which prior pregnancies ended, what the outcomes of the pregnancies were (birth, health baby, death, baby with a birth defect, termination, miscarriage etc), as well as factors such as maternal age, in relation to the risks in subsequent pregnancies. The expected outcomes and significance of the study are: * new evidence about factors causing adverse outcomes of pregnancy; * better information on the risk of recuurence of common birth defects; * more precise information on risks of adverse pregnancy outcomes for users and planners of maternity services.Read moreRead less