Bioanalytical Microchips Based on Integrated, Application Tailored Monolithic Modules. Microfluidic devices offer substantial advantages over current technology, in terms of speed, cost of analysis, portability, operator simplicity and safety. Integrating multiple analytical processes within a simple and reliable portable device will lead to application in a range of areas, from pharmacology to therapeutic drug monitoring, proteomic and metabolomic screening for disease diagnosis and drug develo ....Bioanalytical Microchips Based on Integrated, Application Tailored Monolithic Modules. Microfluidic devices offer substantial advantages over current technology, in terms of speed, cost of analysis, portability, operator simplicity and safety. Integrating multiple analytical processes within a simple and reliable portable device will lead to application in a range of areas, from pharmacology to therapeutic drug monitoring, proteomic and metabolomic screening for disease diagnosis and drug development, and also for performing clinical diagnostics in a rural area. This will significantly impact on the quality of life of the Nation as a whole, not only due to expedient diagnosis and treatment which has obvious health benefits, but also in the considerable financial benefits that result from early and efficient treatment. Read moreRead less
Solid-state light sources for bio-imaging and microfluidics. Solid state light sources are the light sources of the 21st century. This project will allow us to find new ways of bioimaging in living organisms applicable to diagnosing disease, and for microfluidic chip based portable instruments for on-site and point-of-care analysis in medical diagnostics, environmental monitoring, and manufacturing processes.
A high speed, high fidelity 3D printer for fabricating microfluidic devices. This project aims to develop a novel 3D printer offering the highest resolution available and fastest printing speed for the single-step manufacturing of complex microfluidic devices. New resins developed to exploit the inert liquid interface layer printing approach will provide unprecedented capability to create micron sized channels interconnected in 3D space and fabricate Lab-on-a-Chip systems that cannot be generate ....A high speed, high fidelity 3D printer for fabricating microfluidic devices. This project aims to develop a novel 3D printer offering the highest resolution available and fastest printing speed for the single-step manufacturing of complex microfluidic devices. New resins developed to exploit the inert liquid interface layer printing approach will provide unprecedented capability to create micron sized channels interconnected in 3D space and fabricate Lab-on-a-Chip systems that cannot be generated by any current fabrication approach. This novel high speed, high fidelity 3D printer and the new resins to be developed are expected to lead to more effective manufacturing approaches for portable chemical devices and to promote complex chemical analysis into the knowledge immediacy culture of today.Read moreRead less
Everyday Incivilities. The study aims to provide the best available evidence on the seriousness of everyday incivilities between strangers in public places as a social problem in Australian society. This will involve gathering self-report data from socially diverse Australians for the purpose of exploring social group differences in (i) the type and prevalence of everyday incivilities experienced, and (ii) the social and psychological costs of exposure to everyday incivilities. The information ....Everyday Incivilities. The study aims to provide the best available evidence on the seriousness of everyday incivilities between strangers in public places as a social problem in Australian society. This will involve gathering self-report data from socially diverse Australians for the purpose of exploring social group differences in (i) the type and prevalence of everyday incivilities experienced, and (ii) the social and psychological costs of exposure to everyday incivilities. The information gathered will be used to identify high risk social groups and public places, and serve as a basis for developing programs for reducing everyday incivilities.Read moreRead less
The Effectiveness of Forensic Science in the Criminal Justice System. Policing plays a major role in combating crime in the community, reassuring and assisting persons affected by crime so that they can continue, or return, to enjoying their lives. Forensic science is increasingly relied upon by law enforcement to solve crime, and by the judicial system to prosecute offenders. However, the value and impact of forensic science has yet to be established. Through a comprehensive examination of fore ....The Effectiveness of Forensic Science in the Criminal Justice System. Policing plays a major role in combating crime in the community, reassuring and assisting persons affected by crime so that they can continue, or return, to enjoying their lives. Forensic science is increasingly relied upon by law enforcement to solve crime, and by the judicial system to prosecute offenders. However, the value and impact of forensic science has yet to be established. Through a comprehensive examination of forensic science usage in the criminal justice system in Victoria and ACT, this research will develop an evidence-based best-practice model for using forensic science efficiently and effectively. This will benefit the Australian community through the achievement of better and more cost effective criminal justice outcomes. Read moreRead less
Enhancing Selectivity and Detection in Miniaturised Analytical Separation Systems. Miniaturisation-compatible stationary phases and detection techniques will be developed for microseparation techniques of capillary electrochromatography and chip-based separation systems, and their analytical applications will be investigated. Replaceable stationary phases (RSP) of chromatographic particles suspended in reversible gels will be created by delivering a liquid RSP to the column followed by in situ ....Enhancing Selectivity and Detection in Miniaturised Analytical Separation Systems. Miniaturisation-compatible stationary phases and detection techniques will be developed for microseparation techniques of capillary electrochromatography and chip-based separation systems, and their analytical applications will be investigated. Replaceable stationary phases (RSP) of chromatographic particles suspended in reversible gels will be created by delivering a liquid RSP to the column followed by in situ immobilisation. This approach offers flexibility in optimising a number of parameters of the column and of its use for sample pre-treatment and preconcentration. Pulsed potentiometric detection will be developed for the abovementioned microseparation techniques, combining the advantages of pulsed amperometric techniques with the more universally responding potentiometric detection.Read moreRead less
Community Policing and Refugee Settlement in Regional Australia - A Case Study of Tasmania. This project will describe, analyse and theorise police-refugee relations in regional Australia. It compares refugee settlement in three rural/regional areas in Tasmania through the lens of police-refugee relations. In particular, it will identify ways in which community policing can enhance settlement experiences and reduce crime among refugees in regional Australia. It is significant in that it examines ....Community Policing and Refugee Settlement in Regional Australia - A Case Study of Tasmania. This project will describe, analyse and theorise police-refugee relations in regional Australia. It compares refugee settlement in three rural/regional areas in Tasmania through the lens of police-refugee relations. In particular, it will identify ways in which community policing can enhance settlement experiences and reduce crime among refugees in regional Australia. It is significant in that it examines both positive and negative aspects of community policing in the context of refugee settlement in regional Australia in order to develop a best-practice model. Given the Government's recent policy of encouraging settlement in regional Australia, there is an urgent need to analyse these processes. Read moreRead less
Improving Stroke Outcomes: Attenuating Progression And Recurrence
Funder
National Health and Medical Research Council
Funding Amount
$9,331,996.00
Summary
Stroke is the second most common cause of death and major cause disability. There are few proven interventions, so we need to introduce new ones. We developed a bench to bedside program to introduce new stroke therapies and its early secondary prevention. Our general goal is to provide evidence for their effectiveness and safety. We will use animal stroke models, markers in the blood to help diagnose and predict stroke outcome and imaging to help select patients for several clinical trials.
Modelling Food Expenditure, Analysing Nutrient Security, Measuring Hunger and Calculating Purchasing Power Parity: Methodological Advances with Policy Applications. The analysis of consumption changes in selected Asian countries will throw light on Australia's trade potential, especially with one of the fastest growing countries.
More informed debate on the role of trade and aid in reducing hunger and poverty.Following the 2000 Millenium summit and the step up of Australian developmental aid, ....Modelling Food Expenditure, Analysing Nutrient Security, Measuring Hunger and Calculating Purchasing Power Parity: Methodological Advances with Policy Applications. The analysis of consumption changes in selected Asian countries will throw light on Australia's trade potential, especially with one of the fastest growing countries.
More informed debate on the role of trade and aid in reducing hunger and poverty.Following the 2000 Millenium summit and the step up of Australian developmental aid, the subject has returned to the centre stage in policy discussions.
The systematic use of unit value information available elsewhere, but currently lacking in ABS data, will help the latter in improving its HES.
Contribute to "understanding our region and the world"(Key Priority Goal in Research Priority 4 of ARC).
Provide data sets for use in Australian RHD dissertations .
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The Derwent project: immersive digital media visualisations for the representational problems of complex and remote environments. The Derwent Project will create new ways to visualise the complex natural and cultural history of Tasmania’s Derwent River system. This vast and often inaccessible environment includes Aboriginal and colonial heritage alongside ten hydroelectric developments. Its multiple layers of space and time present new opportunities to synthesise artistic and scientific paradigm ....The Derwent project: immersive digital media visualisations for the representational problems of complex and remote environments. The Derwent Project will create new ways to visualise the complex natural and cultural history of Tasmania’s Derwent River system. This vast and often inaccessible environment includes Aboriginal and colonial heritage alongside ten hydroelectric developments. Its multiple layers of space and time present new opportunities to synthesise artistic and scientific paradigms of representation by drawing on geography, history, and archaeology. The outcome will be innovative forms of immersive time-based digital imaging that evocatively reveal hidden layers of environmental information to both specialist and general audiences.Read moreRead less