A Multi-site Randomised Controlled Trial Comparing The Severity Of Constipation Symptoms Experienced By Palliative Care Patients Receiving Usual Care Compared To Those Diagnosed And Managed According To The Underlying Pathophysiology.
Funder
National Health and Medical Research Council
Funding Amount
$498,795.00
Summary
This research aims to consider whether the problems of constipation in palliative care are less severe when the physical changes that underlie the problem are explored.
Characterisation Of Eurl, A Novel Gene Implicated In The Etiology Of Abnormal Brain Development And Intellectual Disability
Funder
National Health and Medical Research Council
Funding Amount
$597,541.00
Summary
Intellectual disability affects around one per cent of Australians, and can arise from genetic abnormalities during fetal life, such as through abnormal regulation of gene expression. We have identified a novel gene, known as eurl, which controls brain assembly as well as the ability of neurons to form functional connections within the brain. We will investigate how this novel gene controls brain development, and characterise eurl as a potential therapeutic target for learning and memory.
Support needs assessment: a developmental model for use in support, training and funding for individuals with single and multiple disabilities. This research project aims to construct and trial a new model for the assessment of the support needs of persons with disabilities. It addresses a number of critical deficiencies which recent research has shown to undermine the reliability, validity and usefulness of existing support needs instruments. Specifically, it is proposed to collect data that ....Support needs assessment: a developmental model for use in support, training and funding for individuals with single and multiple disabilities. This research project aims to construct and trial a new model for the assessment of the support needs of persons with disabilities. It addresses a number of critical deficiencies which recent research has shown to undermine the reliability, validity and usefulness of existing support needs instruments. Specifically, it is proposed to collect data that will inform the determination of the support needs of people with different kinds and combinations of disabilities. Variations in maintenance and intervention supports over time and context will be considered. The assessment system planned will have the flexibility to meet a number of potential user objectives.Read moreRead less
Using Epidemiology To Inform Psychiatric Classification (DSM-V And ICD-11)
Funder
National Health and Medical Research Council
Funding Amount
$631,502.00
Summary
Classification systems are vital for scientific progress. The classifications of mental disorders of the World Health Organization and the American Psychiatric Association are both being revised and this Australian team is a principal contributor to both processes. We have access to three national epidemiological surveys (n-30,000) that will inform fundamental issues by developing models of mental disorder typology and identifying practical improvements in the classification systems.
Negotiating caring and employment - the impact on carers' wellbeing. Work and caring compete for carers? time. Little is known about the difficulties of combining work with the care of adults or children with disabilities. Between 40 and 60 percent of Australian carers combine employment with caring responsibilities. The project proposes to adopt a life-course perspective to study the effect of caring on income security, social participation and the health of employed carers. It makes innovative ....Negotiating caring and employment - the impact on carers' wellbeing. Work and caring compete for carers? time. Little is known about the difficulties of combining work with the care of adults or children with disabilities. Between 40 and 60 percent of Australian carers combine employment with caring responsibilities. The project proposes to adopt a life-course perspective to study the effect of caring on income security, social participation and the health of employed carers. It makes innovative use of existing data sources, including new longitudinal survey data, supported by a specially designed program of qualitative research to study key transitions, possible workplace solutions and the effective provision of human services.Read moreRead less
Remote Aboriginal families and carers of children with disabilities. The project intends to explore the challenges that Aboriginal families who have children with disabilities experience when living in remote communities. Living in a community with family supports is important for the wellbeing, health and spirituality of Aboriginal people in the Ngaanyatjarra Pitjantjara Yankunytjatjara (NPY) lands. However, the NPY Women’s Council are concerned that this is a significant challenge for families ....Remote Aboriginal families and carers of children with disabilities. The project intends to explore the challenges that Aboriginal families who have children with disabilities experience when living in remote communities. Living in a community with family supports is important for the wellbeing, health and spirituality of Aboriginal people in the Ngaanyatjarra Pitjantjara Yankunytjatjara (NPY) lands. However, the NPY Women’s Council are concerned that this is a significant challenge for families and carers of children with disabilities. Project results will be used to propose models for supporting children with disabilities and their families and caregivers to live good lives in their communities. The outcomes are expected to inform service redesign to allow Aboriginal people to fully benefit from the National Disability Insurance Scheme.Read moreRead less
Neural migration: Which cells advance and which stay behind? This project aims to examine the neural crest cells that colonise the developing gut and to identify why some cells advance while others stay behind to populate a region. Directed cell migration is essential for normal development, including for the nervous system. In most of the migratory cell populations that have been analysed to date, all of the cells migrate as a collective from one location to another. However, there are also mi ....Neural migration: Which cells advance and which stay behind? This project aims to examine the neural crest cells that colonise the developing gut and to identify why some cells advance while others stay behind to populate a region. Directed cell migration is essential for normal development, including for the nervous system. In most of the migratory cell populations that have been analysed to date, all of the cells migrate as a collective from one location to another. However, there are also migratory cell populations that must populate the areas through which they migrate, and thus some cells get left behind while others advance. The planned data are likely to be relevant to other cell populations that also populate the areas through which they migrate, including neural crest-derived melanocytes and Schwann cell precursors.Read moreRead less