Sibling influence on development of children with autism spectrum disorder. This project aims to investigate how typically-developing siblings affect the development of children with autism spectrum disorder (ASD). ASD involves difficulties with language, executive functions and social understanding. For typically-developing children, growing up with siblings gives an advantage in these cognitive functions. Yet little is known about how having siblings’ impacts on cognitive development of childr ....Sibling influence on development of children with autism spectrum disorder. This project aims to investigate how typically-developing siblings affect the development of children with autism spectrum disorder (ASD). ASD involves difficulties with language, executive functions and social understanding. For typically-developing children, growing up with siblings gives an advantage in these cognitive functions. Yet little is known about how having siblings’ impacts on cognitive development of children with ASD. The project intends to longitudinally explore the mechanisms of sibling impact in families with and without a child with ASD. The outcomes will deepen understanding of child development, providing an evidence base for effective interventions to increase child competence and aiming ultimately to reduce the social costs of ASD.Read moreRead less
Engaging the over 50s to ensure the sustainability of our blood supply. Australia faces blood shortages as our population ages and demand for blood-product derived treatments increase. Donors aged over 50 donate more regularly with fewer adverse events than younger donors, yet comprise under 24% of blood donors. This multi-method project aims to investigate how those aged over 50 understand and engage with blood donation in the context of ageing, and how their involvement can be managed to maint ....Engaging the over 50s to ensure the sustainability of our blood supply. Australia faces blood shortages as our population ages and demand for blood-product derived treatments increase. Donors aged over 50 donate more regularly with fewer adverse events than younger donors, yet comprise under 24% of blood donors. This multi-method project aims to investigate how those aged over 50 understand and engage with blood donation in the context of ageing, and how their involvement can be managed to maintain psychosocial wellbeing. This project expects to generate new knowledge in recruiting, retaining, and deferring older blood donors. Expected outcomes include tailored, validated resources that may significantly benefit Australia by effectively engaging older adults to ensure the sustainability of the blood supply.Read moreRead less
ARC/NHMRC Research Network in Ageing Well. The ARC Research Network on Ageing Well will support interdisciplinary, high quality research in the National Research Priority Goal of Ageing Well, Ageing Productively. It will build scale and focus on Australia's notable research strengths in ageing, promote collaborative research, and extend research capacities. The Network will link outstanding researchers from many disciplines, nurture developing researchers, relate social to health researchers, s ....ARC/NHMRC Research Network in Ageing Well. The ARC Research Network on Ageing Well will support interdisciplinary, high quality research in the National Research Priority Goal of Ageing Well, Ageing Productively. It will build scale and focus on Australia's notable research strengths in ageing, promote collaborative research, and extend research capacities. The Network will link outstanding researchers from many disciplines, nurture developing researchers, relate social to health researchers, strengthen international collaboration, and involve and inform end-point users. It will foster research which responds to the aspirations and needs of older Australians and informs action that can improve experiences of individual and population ageing.Read moreRead less
Macrophage control of mammalian growth and development. The immediate postnatal period in mammals is crucial for survival, long term health and productivity. This project is an international collaboration that aims to investigate how cells of the innate immune system called macrophages control somatic growth and development of mature organ function in the early postnatal period. The project aims to build upon investment in new animals models and a novel discovery to generate significant new know ....Macrophage control of mammalian growth and development. The immediate postnatal period in mammals is crucial for survival, long term health and productivity. This project is an international collaboration that aims to investigate how cells of the innate immune system called macrophages control somatic growth and development of mature organ function in the early postnatal period. The project aims to build upon investment in new animals models and a novel discovery to generate significant new knowledge that will challenge current concepts of mammalian growth control. The outcomes will enhance Australia's international reputation in the fields of physiology, immunology and developmental biology. Read moreRead less
Placental nutrient transport shows how complex traits evolve. This project aims to use amino acid transport in the vertebrate placenta as a model to demonstrate how genes are recruited and modified to produce a major organ. Using an innovative combination of a new technology, selected reaction monitoring, and transcriptomic and molecular approaches, plus carefully selected Australian species pairs, this project will study the evolution of a complex trait (placental amino acid transport). The pr ....Placental nutrient transport shows how complex traits evolve. This project aims to use amino acid transport in the vertebrate placenta as a model to demonstrate how genes are recruited and modified to produce a major organ. Using an innovative combination of a new technology, selected reaction monitoring, and transcriptomic and molecular approaches, plus carefully selected Australian species pairs, this project will study the evolution of a complex trait (placental amino acid transport). The project will provide fundamental advances in our knowledge of the nutrient transport during pregnancy that is required to produce a healthy baby.Read moreRead less
Judges' work, place and psychological health - a national view. This project aims to address the human, juridical and financial costs of judicial officers’ work-related psychological harm. This harm is implicated in early retirement, sick leave and suicide. It threatens appropriate courtroom conduct, procedural fairness and impartial adjudication. The project seeks to generate new knowledge of the stress judicial officers experience and the individual and institutional mechanisms for managing st ....Judges' work, place and psychological health - a national view. This project aims to address the human, juridical and financial costs of judicial officers’ work-related psychological harm. This harm is implicated in early retirement, sick leave and suicide. It threatens appropriate courtroom conduct, procedural fairness and impartial adjudication. The project seeks to generate new knowledge of the stress judicial officers experience and the individual and institutional mechanisms for managing stressors, combining socio-legal and psychological approaches. Expected outcomes include evidence-based understandings to inform recruitment and retention strategies specific to this highly specialized workforce. This should provide significant benefits for judges’ work capacities and courts' delivery of justice.Read moreRead less
Modelling human decision making in complex environments. The project aims to extend quantitative psychological models of simple choice tasks to decision-making with complex stimuli in complex environments. The new formal models are designed to provide a comprehensive account of behaviour, including the choices that are made, how long it takes to make them, and how choices and choice times vary within and between decision-makers. The models would explain how people adapt to changes in task demand ....Modelling human decision making in complex environments. The project aims to extend quantitative psychological models of simple choice tasks to decision-making with complex stimuli in complex environments. The new formal models are designed to provide a comprehensive account of behaviour, including the choices that are made, how long it takes to make them, and how choices and choice times vary within and between decision-makers. The models would explain how people adapt to changes in task demands when dealing with multiple stimuli or performing multiple tasks concurrently under time pressure. The project aims to provide the basic research that is needed to extend psychological models of choice to complex ‘real-world’ tasks, such air traffic control and maritime surveillance.Read moreRead less
The Tasmanian Healthy Brain Project: A Longitudinal Intervention Study To Reduce The Risk Of Ageing-related Cognitive Decline And Dementia
Funder
National Health and Medical Research Council
Funding Amount
$878,792.00
Summary
It has been proposed that engagement in purposeful complex mental stimulation provides protection against dementia. The Tasmanian Healthy Brain Project (THBP) is a unique, large-scale prospective trial that examines whether university-level study in older adult population reduces ageing-related cognitive decline and risk of dementia. This project will also examine how an individual’s genetic profile may influence the potential benefits of complex mental stimulation as well as risk of dementia.
Redefining the molecular mechanism underlying crustacean metamorphosis. This project uses the astonishing lifecycle of lobster larvae to better define the pathways and discover the key genes that regulate crustacean metamorphosis. Where, when, why and how metamorphosis occurs in crustaceans are important factors affecting fisheries recruitment and aquaculture production. The project suggests that the current accepted paradigm for the molecular control of metamorphosis does not apply to lobsters ....Redefining the molecular mechanism underlying crustacean metamorphosis. This project uses the astonishing lifecycle of lobster larvae to better define the pathways and discover the key genes that regulate crustacean metamorphosis. Where, when, why and how metamorphosis occurs in crustaceans are important factors affecting fisheries recruitment and aquaculture production. The project suggests that the current accepted paradigm for the molecular control of metamorphosis does not apply to lobsters and possibly other crustaceans where larval metamorphosis and the juvenile transformation are uncoupled. Using a unique supply of cultured lobsters and advanced molecular techniques, the project aims to develop tools to trigger and synchronise metamorphosis for use in aquaculture and invasive species management.Read moreRead less
Aboriginal and non-Aboriginal sex-offenders in Australia: Assessing risk for practice and policy. A key priority of Australian governments is to improve community safety through reducing the risk of sex offenders re-offending after release from prison. This project will assess the validity of tools used to predict the risk of sexual offender recidivism and identify alternate risk assessment tools for Indigenous and non-Indigenous sex offenders.