Preparing Australia For Genomic Medicine: A Proposal By The Australian Genomics Health Alliance
Funder
National Health and Medical Research Council
Funding Amount
$25,000,000.00
Summary
The sequencing of the human genome brings the possibility of more accurate identification of the underlying basis of many diseases. This technology has moved so rapidly, however, that clinical access has been limited. In this application, a national alliance of clinicians, researchers, health economists and policymakers will evaluate the case for clinical genomics across inherited disease and cancer, determine how best to deliver this to the patient and train a capable workforce.
Acute rheumatic fever (ARF) and rheumatic heart disease (RHD) are a major problem for Australian Indigenous people. Accurate diagnosis of ARF allows for early preventive therapy with long acting penicillin, which can prevent RHD from developing or worsening. The aim of this study is to recruit a cohort of children and young people with ARF and apply the latest technologies to their blood samples, with the aim of developing a diagnostic test and open leads for potential new treatments.
New Insights Into Viral Inflammatory Disease Mechanisms And Approaches To Therapy
Funder
National Health and Medical Research Council
Funding Amount
$631,010.00
Summary
This fellowship aims to establish how viruses cause disease, including how they evade the immune response to persist and cause disease for prolonged periods. My vision is that knowing how the virus and the immune system interact to determine disease severity will assist in devising new treatments and prevention programs to lessen the impact of viral diseases in Australia and worldwide.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE160100026
Funder
Australian Research Council
Funding Amount
$230,000.00
Summary
VetCompass: Big Data and Real-time Surveillance for Veterinary Science. VetCompass: big data and real-time surveillance for veterinary science:
The VetCompass data service intends to collect real-time records from veterinary clinics and aggregate them for researchers to interrogate. It aims to provide Australian researchers with sustainable and cost-effective access to authoritative data from hundreds of practitioners in Australia and the United Kingdom. These data will be essential for researc ....VetCompass: Big Data and Real-time Surveillance for Veterinary Science. VetCompass: big data and real-time surveillance for veterinary science:
The VetCompass data service intends to collect real-time records from veterinary clinics and aggregate them for researchers to interrogate. It aims to provide Australian researchers with sustainable and cost-effective access to authoritative data from hundreds of practitioners in Australia and the United Kingdom. These data will be essential for research on disease distribution and determinants, and surveillance and diagnostics that underpin evidence-based practice. The expected outcomes include identification of the most prevalent disorders and their causes and optimal treatments. The data may also revolutionise clinical auditing in Australia, help the veterinary profession to rank research priorities, and inform companion animal and equine curricula in our universities.Read moreRead less
Examining scientific, philosophical, and folk perspectives on time=. This project aims to consider three very different physical theories, each of which reconciles quantum mechanics and general and special relativity in a different way. While science is more accessible than ever, we are increasingly faced with a scientific world-view that is antithetical to the way we see the world and experience ourselves in it. This project will consider the tension between the scientific picture of the world ....Examining scientific, philosophical, and folk perspectives on time=. This project aims to consider three very different physical theories, each of which reconciles quantum mechanics and general and special relativity in a different way. While science is more accessible than ever, we are increasingly faced with a scientific world-view that is antithetical to the way we see the world and experience ourselves in it. This project will consider the tension between the scientific picture of the world and our experience of the world, and aims to reconcile the two by bridging the gap between lived experience and scientific findings. The project will provide a range of ways of bridging the tension between these physical theories with our lived experience.Read moreRead less
Early Career Industry Fellowships - Grant ID: IE230100245
Funder
Australian Research Council
Funding Amount
$460,237.00
Summary
Transforming wastewater services in regional Australia. Wastewater treatment in regional Australia faces challenges of odour control, poor pollutant and pathogen removal, and greenhouse gas emissions. This project aims to innovatively use iron salts to realise highly efficient wastewater treatment in regional areas. With Partner, Western Australia Water Corporation, this project expects to leverage a recent breakthrough discovery on iron chemistry to co-develop and field test a solar system that ....Transforming wastewater services in regional Australia. Wastewater treatment in regional Australia faces challenges of odour control, poor pollutant and pathogen removal, and greenhouse gas emissions. This project aims to innovatively use iron salts to realise highly efficient wastewater treatment in regional areas. With Partner, Western Australia Water Corporation, this project expects to leverage a recent breakthrough discovery on iron chemistry to co-develop and field test a solar system that doses wastewater with iron, to overcome four challenges and a supply chain issue simultaneously. Expected outcomes include industry capacity to adopt and commercialise a novel technology with important global relevance. Outcomes should reduce the inequity of wastewater services in regional Australia.Read moreRead less
A Phase III Trial Comparing Adjuvant Versus Salvage Radiotherapy For High Risk Patients Post Radical Prostatectomy
Funder
National Health and Medical Research Council
Funding Amount
$819,138.00
Summary
About half of all patients Treated with an operation to remove their prostate cancer have a high chance of the cancer coming back. Giving immediate radiotherapy to all patients will improve cure rates but does not benefit all men and can cause significant side effects. This study explores whether it is safe to wait and only give radiotherapy when there is a rising PSA after surgery indicating active cancer. A total of 470 men from Australasia will enter this study comparing the two approaches.
Virtue with Aristotle: Recovering an Ancient Ethical Theory for Our Time. This project aims to show how Aristotle’s theory of virtue can guide our individual and collective attempts to live good human lives in challenging times. This project expects to produce the first comprehensive study of Aristotle’s concept of virtue in all three areas of human activity in which he applies it (moral action, theoretical cognition, and craft and artistic production) and to show its relevance for contemporary ....Virtue with Aristotle: Recovering an Ancient Ethical Theory for Our Time. This project aims to show how Aristotle’s theory of virtue can guide our individual and collective attempts to live good human lives in challenging times. This project expects to produce the first comprehensive study of Aristotle’s concept of virtue in all three areas of human activity in which he applies it (moral action, theoretical cognition, and craft and artistic production) and to show its relevance for contemporary ethical theory and practice. Expected outcomes of this project include enhanced understanding of the concepts of virtue and flourishing and their historical roots in Aristotle’s ethical writings. This should provide significant benefits, such as building our collective resilience.Read moreRead less
Exemplary early childhood educators at work: A multi-level investigation. Exemplary early childhood educators at work: A multi-level investigation. This project aims to inform strategies to better attract, prepare, recognise, support and retain a high quality workforce, by investigating the complexity of early childhood educators’ work. Seemingly entrenched workforce shortages threaten the objectives that governments and families seek through investment in early childhood education. Popular imag ....Exemplary early childhood educators at work: A multi-level investigation. Exemplary early childhood educators at work: A multi-level investigation. This project aims to inform strategies to better attract, prepare, recognise, support and retain a high quality workforce, by investigating the complexity of early childhood educators’ work. Seemingly entrenched workforce shortages threaten the objectives that governments and families seek through investment in early childhood education. Popular images of work with young children as easy and instinctual, or of teaching as only school based, mislead potential workforce entrants and erode the status of educators, leading to attrition. This project’s audit and description of exemplary educators’ work, across each level of mandated qualification, will inform strategies to sustain a high quality early childhood workforce into the future.Read moreRead less