Detection and Quantification of General Fetal Movements from Accelerometer Measurements using Nonstationary Signal Processing Techniques. There are approximately 1,750 fetal deaths per year in Australian with about one-third occurring late in gestation and without an apparent cause. The development of an automated system capable of long-term monitoring of fetal health will result in accurate diagnoses and prediction of future outcome. This will, in turn, allow early intervention by the clinicia ....Detection and Quantification of General Fetal Movements from Accelerometer Measurements using Nonstationary Signal Processing Techniques. There are approximately 1,750 fetal deaths per year in Australian with about one-third occurring late in gestation and without an apparent cause. The development of an automated system capable of long-term monitoring of fetal health will result in accurate diagnoses and prediction of future outcome. This will, in turn, allow early intervention by the clinician to reduce fetal deaths and enhance the chances of good outcomes with resultant savings in social and financial costs to the community. The development of such equipment would spawn future research into intervention treatments and contribute to Australia's position as a world leader in computerised health monitoring systems.Read moreRead less
Development of the PD GeneChip: a research and diagnostic tool for Parkinson's disease. The PD GeneChip will provide both social and economic benefits to Australia. It will be a key research platform for Australian scientists, and will facilitate collaboration both within Australia and overseas. It will assist with health care management of PD (Parkinson's disease) patients by providing a cost-effective diagnostic tool and the possibility of predicting the clinical course of disease. This inform ....Development of the PD GeneChip: a research and diagnostic tool for Parkinson's disease. The PD GeneChip will provide both social and economic benefits to Australia. It will be a key research platform for Australian scientists, and will facilitate collaboration both within Australia and overseas. It will assist with health care management of PD (Parkinson's disease) patients by providing a cost-effective diagnostic tool and the possibility of predicting the clinical course of disease. This information will provide the basis for tailoring treatment to a patients needs. It is anticipated that marketing of the PD GeneChip within Australia and overseas may produce revenue of at least $40 million annually.Read moreRead less
DEEP DRILLING OF THE HUMAN PLASMA PROTEOME. Like turning out city lights lets you see the faint stars more clearly - removal of high abundance proteins from human biofluids allows quantum leaps in biomarker discovery. This project will develop products that remove the biggest obstacle in proteomics - high abundance proteins (city lights). Cheap, efficient and routine removal of abundant proteins will amplify the power of ?cutting edge? proteomic technologies in the discovery of novel biomarkers ....DEEP DRILLING OF THE HUMAN PLASMA PROTEOME. Like turning out city lights lets you see the faint stars more clearly - removal of high abundance proteins from human biofluids allows quantum leaps in biomarker discovery. This project will develop products that remove the biggest obstacle in proteomics - high abundance proteins (city lights). Cheap, efficient and routine removal of abundant proteins will amplify the power of ?cutting edge? proteomic technologies in the discovery of novel biomarkers. This is possible because undiscovered low copy number biomarkers (faint stars) exist in human diagnostic fluids at levels far lower than current proteomic array detection limits.Read moreRead less
Special Research Initiatives - Grant ID: SR0354583
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
Biodevice fabrication through intelligent surface modification. Achieving the reliable control of the attachment of proteins and other macromolecules to surfaces needed for sophisticated biosensors and medical diagnostics requires expertise and infrastructure from a diverse range of disciplines from the physical, chemical and biological sciences and engineering. This network will bring together researchers from a multidisciplinary pool working on problems relevant to the creation of functional s ....Biodevice fabrication through intelligent surface modification. Achieving the reliable control of the attachment of proteins and other macromolecules to surfaces needed for sophisticated biosensors and medical diagnostics requires expertise and infrastructure from a diverse range of disciplines from the physical, chemical and biological sciences and engineering. This network will bring together researchers from a multidisciplinary pool working on problems relevant to the creation of functional surfaces for applications in biodevices. The program we envisage will break down the barriers imposed by disciplinary boundaries and technical terminology to bring together the skills and infrastructure required to make rapid advances in this field.Read moreRead less
Next-generation techniques for analysing massive data sets. To process enormous amounts of data, leading computing companies are turning to modern computing frameworks, for which little theory of efficient computational techniques has been developed. This project will resolve key theoretical questions and provide fast techniques for poorly understood pattern recognition and bioinformatics problems.
Cloud-data centres resource allocation under bursty conditions. Cloud-data centres resource allocation under bursty conditions. The project aims to design, implement, and integrate solutions to manage resources in cloud data centres (CDCs), especially when operating under bursty workload conditions. CDCs are expected to assure performance whilst optimising resource usage at a minimum cost, but efficiently providing resources with specific performance requirements can be difficult. This project i ....Cloud-data centres resource allocation under bursty conditions. Cloud-data centres resource allocation under bursty conditions. The project aims to design, implement, and integrate solutions to manage resources in cloud data centres (CDCs), especially when operating under bursty workload conditions. CDCs are expected to assure performance whilst optimising resource usage at a minimum cost, but efficiently providing resources with specific performance requirements can be difficult. This project intends to develop scalable solutions with industry approved software plug-ins. This is expected to affect both trustworthy information and communications technology (ICT) infrastructure (delivering more resilient CDCs) and economic sustainability (reducing CDC usage cost for both users and providers) of today’s computerised society.Read moreRead less
Contention-Aware Scheduling in Cloud Data Centres. This project aims to design, implement, and integrate solutions to improve resource use of private cloud data centres (CDCs). CDCs are expected to guarantee performance while optimising resource usage at a minimum cost. This incurs technical challenges that must be tackled to efficiently provision on-demand resources with specific performance requirements. The project intends to push the applicability of both current techniques and the ones to b ....Contention-Aware Scheduling in Cloud Data Centres. This project aims to design, implement, and integrate solutions to improve resource use of private cloud data centres (CDCs). CDCs are expected to guarantee performance while optimising resource usage at a minimum cost. This incurs technical challenges that must be tackled to efficiently provision on-demand resources with specific performance requirements. The project intends to push the applicability of both current techniques and the ones to be designed in this project to industry-scale CDCs, and identify metrics and variables to holistically control service-level agreements of hosted applications. Scalable solutions with industry approved software plug-ins are the major outcomes of this project. The outcomes of this project will have a substantial impact on both environmental (lowering energy consumption to lead to greener infrastructure) and economic sustainability (reducing cloud usage cost for both users and providers) of today’s much computerised society.Read moreRead less
Special Research Initiatives - Grant ID: SR0354832
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
Dependable Distributed Enterprises and Services. Distributed systems (clusters, grids, peer-to-peer) are the mainstay of many new applications. This has the potential of providing consumers with much more timely, accurate, and comprehensive information on which to base major decisions in financial, medical, and other areas. As with any new technology, related applications should be designed and implemented in such a way that users can depend on the application's availability and results, which i ....Dependable Distributed Enterprises and Services. Distributed systems (clusters, grids, peer-to-peer) are the mainstay of many new applications. This has the potential of providing consumers with much more timely, accurate, and comprehensive information on which to base major decisions in financial, medical, and other areas. As with any new technology, related applications should be designed and implemented in such a way that users can depend on the application's availability and results, which is the main focus of this network. The CIs will collaborate in several ways, ranging from basic research to applications, to enable the creation and maintenance of highly dependable computer systems and networked applications.
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Discovery Early Career Researcher Award - Grant ID: DE150100240
Funder
Australian Research Council
Funding Amount
$315,000.00
Summary
Geometry and Conditioning in Structured Conic Problems. Conic programming allows one to model and solve large industrial problems via modern optimisation methods, such as interior-point algorithms. These methods are efficient and reliable in solving a vast number of problems, however, they fail on a relatively small but significant set of ill-posed instances, thus affecting the overall reliability of the technique. The reason for such behaviour is profound and constitutes one of the major unsolv ....Geometry and Conditioning in Structured Conic Problems. Conic programming allows one to model and solve large industrial problems via modern optimisation methods, such as interior-point algorithms. These methods are efficient and reliable in solving a vast number of problems, however, they fail on a relatively small but significant set of ill-posed instances, thus affecting the overall reliability of the technique. The reason for such behaviour is profound and constitutes one of the major unsolved problems in real complexity: there is no known algorithm that solves conic problems with real data in polynomial time. The project aims to develop a deep understanding of the geometry of conic problems, aiming for the resolution of this fundamental problem in computational theory.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE180100043
Funder
Australian Research Council
Funding Amount
$435,279.00
Summary
High-throughput portable and wearable device fabrication facility. This project aims to establish a fabrication and characterisation facility for high-throughput production of portable, wearable and stretchable biomedical devices to accelerate the design–fabrication–evaluation process and save ‘trial-and-error’ costs during optimisation turnaround. It will apply computer-aided design for the programmable synthesis of hybrid materials for high-throughput screening of disease biomarkers, and super ....High-throughput portable and wearable device fabrication facility. This project aims to establish a fabrication and characterisation facility for high-throughput production of portable, wearable and stretchable biomedical devices to accelerate the design–fabrication–evaluation process and save ‘trial-and-error’ costs during optimisation turnaround. It will apply computer-aided design for the programmable synthesis of hybrid materials for high-throughput screening of disease biomarkers, and super-solution imaging of single molecules in live cells. This facility will provide capability for researchers pursuing industry transformation and other initiatives in the development of advanced materials, biomolecular sciences, nanotechnology, photonics and device engineering.Read moreRead less