Nanoscale Coating and Biomodification of Colloids for Biological Applications. The research entails the preparation of novel biofunctional colloids of nanometer to micrometer dimensions and their utilisation in biological applications. Self-assembly processes will be exploited to achieve nanoscale biomodification of technologically important colloid particles, including latex beads and rare earth and semiconductor nanoparticles. The studies conducted will generate fundamental knowledge pertainin ....Nanoscale Coating and Biomodification of Colloids for Biological Applications. The research entails the preparation of novel biofunctional colloids of nanometer to micrometer dimensions and their utilisation in biological applications. Self-assembly processes will be exploited to achieve nanoscale biomodification of technologically important colloid particles, including latex beads and rare earth and semiconductor nanoparticles. The studies conducted will generate fundamental knowledge pertaining to the underlying factors that govern the formation of biofunctional colloid particles through self-assembly. This is essential for the development of tailored colloids that will meet the demands placed on nanomaterials synthesis and performance by nanotechnology. The colloids prepared will find new applications in medicine, biocatalysis and bioassays.Read moreRead less
Spectroscopy of complex and biological micro-objects for biosensing applications. The optically based test for specific DNA binding resulting from the conclusion of this project is of great potential benefit to all Australians as DNA is the building block of all living organisms. The technique developed and resulting biosensor will provide an invaluable tool for the determination and analysis of specific DNA reactions. The general technique developed for the genetic targeting of specific DNA rea ....Spectroscopy of complex and biological micro-objects for biosensing applications. The optically based test for specific DNA binding resulting from the conclusion of this project is of great potential benefit to all Australians as DNA is the building block of all living organisms. The technique developed and resulting biosensor will provide an invaluable tool for the determination and analysis of specific DNA reactions. The general technique developed for the genetic targeting of specific DNA reactions makes the detection of diseases and toxins like Chlamydia and anthrax, for example cheap, quick and accurate, keeping Australian's healthy, and strengthening national security.Read moreRead less
Nanoengineered Colloids and thin films through self-assembly with potential applications in Bioscince and Nanotechnology. The proposed research program will focus on the preparation, characterisation and application of novel, small (nanometer size) particles and thin (micrometer thick)films derived from such particles. These new and advanced materials will be prepared by usinf a recently developed, highly versatile and facile technology to coat particles in solution. The strategy to be used en ....Nanoengineered Colloids and thin films through self-assembly with potential applications in Bioscince and Nanotechnology. The proposed research program will focus on the preparation, characterisation and application of novel, small (nanometer size) particles and thin (micrometer thick)films derived from such particles. These new and advanced materials will be prepared by usinf a recently developed, highly versatile and facile technology to coat particles in solution. The strategy to be used entails the step-by-step construction of well-defined layers of different composition on particles and flat surfaces, thereby allowing unprecendented control over the material properties and function. This will provide new avenues for the application of nanoscale materials in biotechnology and nanotechnology.Read moreRead less
Metabolic Profiling of Human Embryonic Stem Cells. Stem cell therapies are becoming a commercial reality. Stem cell products have an estimated value of US$ 87 million this year and are predicted to be worth US$ 8.5 billion within a decade. Development of stem cell products will be an international research effort with many contributing to the final products. Research described here will augment this effort, strengthening Australia's contribution by developing novel intellectual property and appl ....Metabolic Profiling of Human Embryonic Stem Cells. Stem cell therapies are becoming a commercial reality. Stem cell products have an estimated value of US$ 87 million this year and are predicted to be worth US$ 8.5 billion within a decade. Development of stem cell products will be an international research effort with many contributing to the final products. Research described here will augment this effort, strengthening Australia's contribution by developing novel intellectual property and applications. The training of individuals skilled in stem cell research will add to Australia's pool of stem cell researchers. Individuals trained in this area will be paramount to maintaining Australia's research effort and in the application of these technologies into the Australian health sector.Read moreRead less