Establishment of Therapeutically Relevant Animal Models and Markers for Crohn's Disease. Crohn's disease is a devastating life long disease, affecting 0.5% of the world population. There is urgent economic and social need to develop new and better drugs to treat the symptoms and underlying cause of this debilitating disease. Social benefits include the improved quality of life of sufferers that positively impacts society. Economic benefit includes income derived from commercialisation of rese ....Establishment of Therapeutically Relevant Animal Models and Markers for Crohn's Disease. Crohn's disease is a devastating life long disease, affecting 0.5% of the world population. There is urgent economic and social need to develop new and better drugs to treat the symptoms and underlying cause of this debilitating disease. Social benefits include the improved quality of life of sufferers that positively impacts society. Economic benefit includes income derived from commercialisation of research outcomes and the contribution this project makes to high value employment in the biotechnology sector.Read moreRead less
Gastrointestinal parasites and their diagnosis. Gastrointestinal disease such as diarrhoea, abdominal pain and irritable bowel syndrome are common in the Australian population and there are a wide variety of causes, including potentially parasites. The parasite Dientamoeba fragilis has, until recently, been overlooked as a cause of human disease, but recent studies have confirmed its role as a pathogen. This project seeks to improve the diagnosis of this organism in faeces and this development ....Gastrointestinal parasites and their diagnosis. Gastrointestinal disease such as diarrhoea, abdominal pain and irritable bowel syndrome are common in the Australian population and there are a wide variety of causes, including potentially parasites. The parasite Dientamoeba fragilis has, until recently, been overlooked as a cause of human disease, but recent studies have confirmed its role as a pathogen. This project seeks to improve the diagnosis of this organism in faeces and this development will allow effective treatment to be used in patients thereby ameliorating disease.Read moreRead less
Development of novel cereal grain products for wheat and gluten intolerant Australians. Many Australians claim to have wheat or gluten intolerances and this has led to the growing demand for wheat and gluten free grain products. The most common problems reported by individuals relate to gut symptoms and chronic fatigue. There are a number of dietary factors in cereal products that may be responsible for triggering these symptoms including the presence of poorly absorbed carbohydrates and wheat g ....Development of novel cereal grain products for wheat and gluten intolerant Australians. Many Australians claim to have wheat or gluten intolerances and this has led to the growing demand for wheat and gluten free grain products. The most common problems reported by individuals relate to gut symptoms and chronic fatigue. There are a number of dietary factors in cereal products that may be responsible for triggering these symptoms including the presence of poorly absorbed carbohydrates and wheat gluten itself. This partnership between Monash University and George Weston Foods will develop novel food products that will be better tolerated by Australians reporting wheat and gluten intolerances. This will help provide the cereal industry with a competitive edge and improve the sustainability of the Australian agriculture sector.Read moreRead less