Centre Of Research Excellence In Medicines Intelligence
Funder
National Health and Medical Research Council
Funding Amount
$2,500,000.00
Summary
The NHMRC Centre of Research Excellence in Medicines Intelligence is a co-ordinated research program that will accelerate the development and translation of evidence on prescribed medicines use and outcomes for regulators and payers. The CRE is perfectly placed to embrace the national ‘call to action’ from the Health Minister's recent announcement to establish Quality Use of Medicine Safety as a National Health Priority.
Re-EValuating The Inhibition Of Stress Erosions (REVISE): Gastrointestinal Bleeding Prophylaxis In ICU
Funder
National Health and Medical Research Council
Funding Amount
$2,955,164.00
Summary
Around 50,000 patients in Australian Intensive Care Units receive a drug called pantoprazole each year with the aim of preventing bleeding from the gut. Recent research suggests this practice is ineffective and may harm patients by increasing their risk of serious infections. We will perform a definitive study to determine whether the widespread use of pantoprazole is beneficial or harmful.
Next-gen accident prevention: a new theory and toolkit for safer systems. This project aims to address limitations associated with existing accident causation theory and methodologies. Accident prevention across high risk industries is constrained by limitations in accident theory and methodologies. As a result, reductions in injuries and fatalities in most domains are plateauing. The expected outputs of the project include a new theory of accident causation, a new proactive risk assessment meth ....Next-gen accident prevention: a new theory and toolkit for safer systems. This project aims to address limitations associated with existing accident causation theory and methodologies. Accident prevention across high risk industries is constrained by limitations in accident theory and methodologies. As a result, reductions in injuries and fatalities in most domains are plateauing. The expected outputs of the project include a new theory of accident causation, a new proactive risk assessment methodology and a new methodology for analysing accidents. This will provide organisations and researchers with a powerful framework for enhanced accident analysis and prevention activities. This will provide significant benefits, associated with reductions in accidents, injuries and fatalities.Read moreRead less
Application of contemporary systems-based methods to reduce trauma at rail level crossings. Crashes at railway level crossings continue to cause significant trauma across Australia. Despite being a longstanding safety problem, the design and operation of level crossings has not changed considerably for decades. This research will provide an in-depth understanding of road user, environmental and infrastructure-related factors that influence safety and performance at rail level crossings. This wil ....Application of contemporary systems-based methods to reduce trauma at rail level crossings. Crashes at railway level crossings continue to cause significant trauma across Australia. Despite being a longstanding safety problem, the design and operation of level crossings has not changed considerably for decades. This research will provide an in-depth understanding of road user, environmental and infrastructure-related factors that influence safety and performance at rail level crossings. This will be used to develop a world-first model of the level crossing system that is needed to support the development of innovative countermeasures that will improve safety. Reductions in the levels of significant trauma at level crossings, and new public policy for level crossing upgrades, are the intended real-world outcomes.Read moreRead less
An Investigation Of The Involvement Of Clotting Factors In Abdominal Aortic Aneurysm (AAA) Progression Within A Mouse Model
Funder
National Health and Medical Research Council
Funding Amount
$189,401.00
Summary
Early stage weakening of the main abdominal artery is present in ~100,000 Australians and currently has no accepted therapy. Development of drug therapies which limit progression of the weakening process is urgently needed. In this study involvement of the clotting cascade in artery weakening will be investigated. The study have been planned in order to identify new strategies which can be developed as treatments for artery weakening in patients.
Industrial Transformation Training Centres - Grant ID: IC160100025
Funder
Australian Research Council
Funding Amount
$2,259,000.00
Summary
ARC Training Centre in Food Safety in the Fresh Produce Industry. ARC Training Centre in Food Safety in the Fresh Produce Industry. This centre aims to create an innovation platform of food safety researchers and industry personnel who can significantly advance the safety of fruit and vegetables in Australia. The intended outcomes are safer food, leading to enhanced health and wellbeing; industry growth in the food/agribusiness sector; enhanced trust and international reputation; and increased a ....ARC Training Centre in Food Safety in the Fresh Produce Industry. ARC Training Centre in Food Safety in the Fresh Produce Industry. This centre aims to create an innovation platform of food safety researchers and industry personnel who can significantly advance the safety of fruit and vegetables in Australia. The intended outcomes are safer food, leading to enhanced health and wellbeing; industry growth in the food/agribusiness sector; enhanced trust and international reputation; and increased access to growing export markets. Intended benefits to industry are ready-to-use technologies for strengthened food safety, and a new generation of highly-skilled food safety scientists with experience in conducting industry-focused research.Read moreRead less
The Australian naturalistic driving study: innovation in road safety research and policy. A revolutionary new approach, the naturalistic driving study, will investigate what people actually do when they drive, in normal and safety-critical situations. It will provide Australia with answers to some intractable, high priority, road safety problems that cannot be answered using current methods, thereby saving hundreds of lives.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE130100050
Funder
Australian Research Council
Funding Amount
$570,000.00
Summary
Integrated facility for recording driver and road user behaviour. The integrated facility will be used to record and analyse data on driver and road user behaviour, in normal and safety-critical situations, for thousands of Australian drivers. The data yielded will be used to develop new and improved countermeasures for reducing road deaths and serious injuries on Australian roads.
Proactive detection of motor vehicle crash black spots based on their underlying behavioural, engineering, and spatially related causes. Road traffic crashes are responsible for about 1400 fatalities and 32,500 injuries on Australian roadways each year. A significant research opportunity exists to fundamentally rethink how the profession quantitatively identifies black spots on the transport network. The first project aim is to develop, test, and validate an evidence based methodology to proacti ....Proactive detection of motor vehicle crash black spots based on their underlying behavioural, engineering, and spatially related causes. Road traffic crashes are responsible for about 1400 fatalities and 32,500 injuries on Australian roadways each year. A significant research opportunity exists to fundamentally rethink how the profession quantitatively identifies black spots on the transport network. The first project aim is to develop, test, and validate an evidence based methodology to proactively detect motor vehicle crash black spots. The second aim is decompose (statistically) observed crashes at a site into their engineering, behavioural, and unobserved spatial components. The new methods combined will lead to fundamentally novel insights and knowledge regarding transport network safety management, in turn leading to reductions in the Australian road toll.Read moreRead less
A new generation high crash energy absorbing barrier for improved road safety. The new, high energy absorbing road safety barrier developed in this project will provide better protection for all road users than current barriers by reducing the severity of car crashes. Current road barriers result in an average loss of 1600 lives in Australia annually, including a disproportionate number of young lives. The new barrier will be highly efficient in absorbing collisions from vehicles travelling at s ....A new generation high crash energy absorbing barrier for improved road safety. The new, high energy absorbing road safety barrier developed in this project will provide better protection for all road users than current barriers by reducing the severity of car crashes. Current road barriers result in an average loss of 1600 lives in Australia annually, including a disproportionate number of young lives. The new barrier will be highly efficient in absorbing collisions from vehicles travelling at speeds between 60 to over a 100 kilometres per hour. Installation of the new road safety barrier systems in high accident zones will save lives by reducing the severity of accidents involving road barriers. This will significantly benefit the community by reducing injury, medical, rehabilitation and property damage costs, and improve quality of life for all road users.Read moreRead less