Genetic Mechanisms That Moderate Effects Of Aβ Accumulation In Preclinical Alzheimer's Disease
Funder
National Health and Medical Research Council
Funding Amount
$603,525.00
Summary
Alzheimer’s disease (AD) is the most common form of dementia, and the number of people living with it will triple by 2050. There is currently no cure for AD, and the only means of slow the growing epidemic is to delay onset. We propose to understand the complex interplay between genetic, cognitive, neuroimaging and biological markers of AD in order to better understand the disease process, and in turn identify high-risk individuals for clinical trials and uncover disease-modifying strategies.
The Role Of Renal Dendritic Cells In Infection And Immunity Under Immunosuppression
Funder
National Health and Medical Research Council
Funding Amount
$475,143.00
Summary
Kidney transplantation is the best treatment for kidney failure but it is frequently complicated by bacterial and viral infections that can cause rejection and may cause loss of the kidney. This grant will study the role that dendritic cells in the kidney play in causing rejection and preventing infection. With the knowledge gained from these studies, we will be able to discover new ways to prevent rejection and treat infections of the kidney post transplant.
Discovery Early Career Researcher Award - Grant ID: DE230100652
Funder
Australian Research Council
Funding Amount
$407,500.00
Summary
Toward data justice in Australian schools. This project will investigate the challenges raised by digital data for Australian schools. The use of digital technologies in schools has led to systematic data collection, which reconfigures schooling processes and interpersonal relationships and presents new risks to staff and students. Although there are laws in place to protect students' rights, there are hidden consequences to using digital technologies. This research project investigates how data ....Toward data justice in Australian schools. This project will investigate the challenges raised by digital data for Australian schools. The use of digital technologies in schools has led to systematic data collection, which reconfigures schooling processes and interpersonal relationships and presents new risks to staff and students. Although there are laws in place to protect students' rights, there are hidden consequences to using digital technologies. This research project investigates how data collection, use and disclosure is experienced and understood in schools. It will identify the role played by intermediaries, such as tech brokers, educational authorities and professional networks. Benefits include policy recommendations, protocols and guidelines for data justice in schools.Read moreRead less
Implementation and evaluation of a program to reduce alcohol and related problems among farm men and women. Farming is pivotal to Australia's food production and economy; yet farm communities are under great stress. The Sustainable Farm Families program aims to strengthen rural communities across Australia, and our project will add an important component to it by producing an evidence-based strategy for encouraging farm men and women to adopt more positive alcohol-related behaviours that will l ....Implementation and evaluation of a program to reduce alcohol and related problems among farm men and women. Farming is pivotal to Australia's food production and economy; yet farm communities are under great stress. The Sustainable Farm Families program aims to strengthen rural communities across Australia, and our project will add an important component to it by producing an evidence-based strategy for encouraging farm men and women to adopt more positive alcohol-related behaviours that will lead to better physical and mental health. We expect that our project will reduce the level of dangerous alcohol consumption and enhance the economic, social and cultural fabric of rural Australia.Read moreRead less
Selling The Punt: An interdisciplinary analysis of the extent and impact of sports wagering marketing strategies in Australia. Sports wagering is the fastest growing segment of the gambling market in Australia. Despite widespread concern about the impact of marketing strategies on the risky consumption of wagering products by young men and adolescents, research and policy has failed to keep up with this rapidly growing industry. This study will provide: detailed information about the range of ma ....Selling The Punt: An interdisciplinary analysis of the extent and impact of sports wagering marketing strategies in Australia. Sports wagering is the fastest growing segment of the gambling market in Australia. Despite widespread concern about the impact of marketing strategies on the risky consumption of wagering products by young men and adolescents, research and policy has failed to keep up with this rapidly growing industry. This study will provide: detailed information about the range of marketing strategies used to sell sports wagering in Australia; important qualitative insights into the impact of these marketing strategies on gambling behaviours; and, recommendations for a comprehensive public health approach to help counter the potential long and short term risks associated with sports wagering marketing.Read moreRead less
Maternal mental health and anaemia as determinants of infant health and development in resource constrained settings. A healthy start to life is an explicit Australian priority. Maternal health is a major determinant of the health and development of infants. This international collaborative project will contribute evidence about two maternal health conditions: mental disorders and anaemia, and their effects on infant health and development, through research in Vietnam where both are prevalent. ....Maternal mental health and anaemia as determinants of infant health and development in resource constrained settings. A healthy start to life is an explicit Australian priority. Maternal health is a major determinant of the health and development of infants. This international collaborative project will contribute evidence about two maternal health conditions: mental disorders and anaemia, and their effects on infant health and development, through research in Vietnam where both are prevalent. The findings will inform interventions to improve the health of mothers and infants in all resource-constrained settings, including among indigenous and refugee groups in Australia. It will advance Australia's international relations by strengthening a partnership with Viet Nam and contributing to a World Health Organization priority area. Read moreRead less
The big gamble: an interdisciplinary study of the normalisation of gambling. This project aims to explore industry and socio-cultural factors that contribute to the normalisation of gambling. Gambling is recognised as an urgent public health issue in Australia, posing a health threat to individuals and communities. However, there is limited empirical evidence about the processes that may contribute to the normalisation of different forms of gambling. This project aims to explore the interplay be ....The big gamble: an interdisciplinary study of the normalisation of gambling. This project aims to explore industry and socio-cultural factors that contribute to the normalisation of gambling. Gambling is recognised as an urgent public health issue in Australia, posing a health threat to individuals and communities. However, there is limited empirical evidence about the processes that may contribute to the normalisation of different forms of gambling. This project aims to explore the interplay between the sophisticated promotional tactics used by the gambling industry, and the socio-cultural mechanisms which may interact with these promotional tactics to normalise gambling beliefs in youth, women, and older adults. This project expects to help local governments and related stakeholders develop a comprehensive range of public health strategies aimed at preventing the risks and harms posed by the normalisation of gambling.Read moreRead less
Individual, social and physical environmental influences on children's active transport and independent mobility. Childhood obesity is likely to have significant economic and social impacts on Australian society. Preventing further increases in this disease is crucial, particularly among children at high risk such as those living in rural or disadvantaged areas. The promotion of behaviours such as active transport may have a significant benefit for public health; however little is known about wh ....Individual, social and physical environmental influences on children's active transport and independent mobility. Childhood obesity is likely to have significant economic and social impacts on Australian society. Preventing further increases in this disease is crucial, particularly among children at high risk such as those living in rural or disadvantaged areas. The promotion of behaviours such as active transport may have a significant benefit for public health; however little is known about what influences active transport among children in rural or disadvantaged areas. This study will identify important factors influencing active transport and will directly inform strategies aiming to promote health and wellbeing, thereby creating a healthier generation of Australian children.Read moreRead less
Weight stigma in the preconception, pregnancy and postpartum periods. The overall aim of this project is to develop guidance for the translation of weight stigma evidence into preconception, pregnancy and postpartum obesity-related policy. It focuses on the socio-ecological factors that perpetuate weight stigma in women across the reproductive life phase, that is, in women planning a pregnancy, in women who are pregnant and in mothers who have given birth within a 24-month period.
Social and health inequalities related to changes in drinking water in rural Victoria. This project will add significantly to knowledge about the role of water in health. Dental caries (decay) experience over an individual's life time is influenced by dental health in early childhood. Obesity and overweight in early childhood is also a predictor of later life obesity. Both these conditions reduce life chances and wellbeing for Australians and are costly for communities. Understanding why and how ....Social and health inequalities related to changes in drinking water in rural Victoria. This project will add significantly to knowledge about the role of water in health. Dental caries (decay) experience over an individual's life time is influenced by dental health in early childhood. Obesity and overweight in early childhood is also a predictor of later life obesity. Both these conditions reduce life chances and wellbeing for Australians and are costly for communities. Understanding why and how choices about drinks for children are made by parents using a longitudinal design will help to develop interventions and policies that support the use of water in preference to sweetened and acidic beverages. Read moreRead less