Neurodevelopmental disorders and loneliness: School predictors & outcomes. This project aims to establish trajectories of loneliness across the 10-18 year developmental period in adolescents with neuro-developmental disorders (NDDs). This is significant because adolescence is the peak period for loneliness and the social communication difficulties experienced by adolescents with NDDs place them at greater risk of loneliness. Lower levels of school attendance, connectedness and mental well-being, ....Neurodevelopmental disorders and loneliness: School predictors & outcomes. This project aims to establish trajectories of loneliness across the 10-18 year developmental period in adolescents with neuro-developmental disorders (NDDs). This is significant because adolescence is the peak period for loneliness and the social communication difficulties experienced by adolescents with NDDs place them at greater risk of loneliness. Lower levels of school attendance, connectedness and mental well-being, and higher rates of disruptive behaviour, expulsion, drop-out, depression, social withdrawal, and suicide ideation are strongly linked to loneliness. Therefore predicting critical times in trajectories will enhance emotional, behavioural and school related outcomes and optimise economic, societal and quality of life benefits.Read moreRead less
Structural relations of loners' loneliness and antisocial behaviour in children and adolescents: building a conceptual model for effective intervention. This is the first research project to develop a conceptual model of loneliness and detached a-loneness to explain the contribution of loneliness to childhood and adolescent antisocial behaviour. The outcome will be a school-based web delivered program which will have a major impact on promoting the healthy development of young Australians.
A cluster randomised controlled trial of a school-based physical activity intervention in at-risk communities. This project will test the effect of a professional development program targeting physical education teachers, designed to increase students' opportunities to do physical activity during physical education lessons. It will focus on how to enhance their motivation to not only be physically active during physical education lessons, but also outside school hours.
The role of mechanosensitive (MS) ion channels in magnetoreception. The magnetic field of the Earth has for long been known to influence the behaviour and orientation of a variety of organisms. Experimental study of the magnetic sense has however, been impaired by the lack of a plausible cellular and/or molecular mechanism providing meaningful explanation for detection of magnetic fields by living organisms. Recently, mechanosensitive (MS) ion channels have been implied to play a role in magneto ....The role of mechanosensitive (MS) ion channels in magnetoreception. The magnetic field of the Earth has for long been known to influence the behaviour and orientation of a variety of organisms. Experimental study of the magnetic sense has however, been impaired by the lack of a plausible cellular and/or molecular mechanism providing meaningful explanation for detection of magnetic fields by living organisms. Recently, mechanosensitive (MS) ion channels have been implied to play a role in magnetoreception. Based on our preliminary investigations, which suggest that the activity of bacterial MS channels may be affected by magnetic fields, we propose to study effects of magnetic fields on MS ion channels in Gram-negative bacteria Escherichia coli and Magnetospirillum magnetotacticum. The project promises also to contribute towards better understanding of adverse effects of electromagnetic radiation on human health and towards understanding the mechanisms behind remote magnetic-nanoparticle mediated activation of MS ion channels.Read moreRead less
The Ancient Today: Living Traditions of Classical Language Education. This project aims to compare, for the first time, ancient language education across world cultures with ‘classical’ literatures. It expects to illumine the purpose and value of classical language education in Chinese, Greek, Latin, and Sanskrit historically and within global education systems today by comparing pedagogic ideals and practices across times and cultures. It aims to test the potential of inclusive classical langua ....The Ancient Today: Living Traditions of Classical Language Education. This project aims to compare, for the first time, ancient language education across world cultures with ‘classical’ literatures. It expects to illumine the purpose and value of classical language education in Chinese, Greek, Latin, and Sanskrit historically and within global education systems today by comparing pedagogic ideals and practices across times and cultures. It aims to test the potential of inclusive classical language learning to boost educational outcomes for disadvantaged students. Other expected outcomes include two books, scholarly articles, education policy reports, and PhD student training. This should strengthen intercultural understanding and benefit school students, educators, policy makers and the wider public.Read moreRead less
Goal orientations, self-regulation and performance: Implications for accelerating learning via goal-setting interventions. This project relates to the priority of strengthening Australia's social and economic fabric. The question of when and why various goals are adaptive versus maladaptive is of fundamental importance for understanding human behaviour. Society benefits from research into this question, because it provides a pathway for tapping into human potential. The results have implications ....Goal orientations, self-regulation and performance: Implications for accelerating learning via goal-setting interventions. This project relates to the priority of strengthening Australia's social and economic fabric. The question of when and why various goals are adaptive versus maladaptive is of fundamental importance for understanding human behaviour. Society benefits from research into this question, because it provides a pathway for tapping into human potential. The results have implications for the development of effective training programs and thus have the potential to influence personal growth and financial stability. The results will have wide application in a variety of industries. Examples include the development of interventions for more rapid training, and the development of performance-management plans for facilitating career advancement.Read moreRead less
Early evolutionary origins of mechanosensory transduction: structure, function and phylogenetic studies of the family of mechanosensitive channels in cell-walled organisms. The proposed project is based on the recent progress the applicants have made by (i) identifying a novel family of mechanosensitive (MS) channels in cell-walled organisms, which include Archaea and Bacteria (prokaryotes), as well as fungi and plants (eukaryotes), and (ii) determining basic aspects of the structural dynamics ....Early evolutionary origins of mechanosensory transduction: structure, function and phylogenetic studies of the family of mechanosensitive channels in cell-walled organisms. The proposed project is based on the recent progress the applicants have made by (i) identifying a novel family of mechanosensitive (MS) channels in cell-walled organisms, which include Archaea and Bacteria (prokaryotes), as well as fungi and plants (eukaryotes), and (ii) determining basic aspects of the structural dynamics of MscL, the prototype MS channel, using electronparamagnetic resonance spectroscopy and molecular dynamics simulations in combination with the patch clamp technique. The aim of the project is to elucidate the molecular principles underlying the function of MS channels, which is of fundamental importance for understanding of the biophysics and physiology of mechanosensory transduction throughout the biological world.Read moreRead less
Engaging Students during the Early Years of Secondary School. This project aims to design, test and share sustainable strategies to support teachers and enable students from low socioeconomic communities to achieve success. The greatest decreases in students’ interest and effort occur when they transition into secondary school, with students from low socioeconomic communities at greatest risk of disengagement. What can teachers do to engage their students during this key life transition? This pr ....Engaging Students during the Early Years of Secondary School. This project aims to design, test and share sustainable strategies to support teachers and enable students from low socioeconomic communities to achieve success. The greatest decreases in students’ interest and effort occur when they transition into secondary school, with students from low socioeconomic communities at greatest risk of disengagement. What can teachers do to engage their students during this key life transition? This project plans to identify teacher behaviours that motivate students in their first year at secondary school. Using an experimental design with a representative sample of 150 teachers and 1500 students in low socioeconomic areas across three states, the project plans to test whether an online professional learning program for teachers can improve student engagement and achievement. This cost-effective and scalable intervention is designed for widespread dissemination to Australian teachers.Read moreRead less
Social, economic and health vulnerabilities in Indonesia. This project aims to study and provide ways to overcome vulnerability in Indonesia. Half the Indonesian population is still clustered around the poverty line, contributing to their vulnerability. This project will identify vulnerable groups and why they are vulnerable. Using a common framework of the life course in eight Indonesian field sites, this project will investigate whether social networks and welfare programs reduce vulnerability ....Social, economic and health vulnerabilities in Indonesia. This project aims to study and provide ways to overcome vulnerability in Indonesia. Half the Indonesian population is still clustered around the poverty line, contributing to their vulnerability. This project will identify vulnerable groups and why they are vulnerable. Using a common framework of the life course in eight Indonesian field sites, this project will investigate whether social networks and welfare programs reduce vulnerability, and pinpoint strategies for reducing vulnerabilities in the future. The project expects to show how vulnerable citizens in Indonesia can be made more secure, helping to build a more stable and prosperous region.Read moreRead less
Force from lipids: the role of the lipid bilayer in mechanosensory transduction. The proposed research will significantly contribute to a better understanding of the wide range of physiological processes underlying mechanosensory transduction in living cells. The direct benefit for Australian science consists of: (i) strengthening international links with leading overseas laboratories, and (ii) accessing the state-of-the-art expertise not available in Australia. The acquired knowledge will aid i ....Force from lipids: the role of the lipid bilayer in mechanosensory transduction. The proposed research will significantly contribute to a better understanding of the wide range of physiological processes underlying mechanosensory transduction in living cells. The direct benefit for Australian science consists of: (i) strengthening international links with leading overseas laboratories, and (ii) accessing the state-of-the-art expertise not available in Australia. The acquired knowledge will aid in developing and designing artificial tactile sensors inspired by their biological models studied in this project. Long-term, the project is expected to make an original contribution towards developing new technologies and novel medical applications, both of which promise to be of great national benefit.Read moreRead less