Surveillance And Treatment Of Prisoners With Hepatitis C (SToP-C)
Funder
National Health and Medical Research Council
Funding Amount
$1,560,494.00
Summary
SToP-C will investigate whether a significant reduction in hepatitis C infection in NSW prisons is possible with a “treatment as prevention” strategy. It will treat prisoners for hep C infection both to improve their own health and to make onward transmission to others less likely. There is currently a lack of available effective strategies; however through delivery of simple, effective new therapies this world-first trial offers significant opportunities to reduce the burden of liver disease.
Novel Artemisinin-based Combination Therapies For Children Exposed To High Transmission Of Multiple Plasmodium Species
Funder
National Health and Medical Research Council
Funding Amount
$1,378,408.00
Summary
We recently found that the WHO-recommended combination antimalarial therapy artemether-lumefantrine and the candidate regimen dihydroartemisinin-piperaquine were not fully effective for both falciparum and vivax malaria in young PNG children, a group at risk of complications and death. We plan to study two new combinations (artesunate-pyronaridine and artemisinin-naphthoquine) and hypothesise that at least one will prove superior and be used as first-line treatment in PNG and similar countries.
Adapting Pandemic Influenza Interventions And Management To The Newly-emerged Virus
Funder
National Health and Medical Research Council
Funding Amount
$245,098.00
Summary
The Australian Health Management Plan for Pandemic Influenza is based on data from past and current influenza. A newly-emerged influenza strain is likely to differ in some respects. This project will develop practical ways to adapt the management plan to the emerged virus from early pandemic data. It will determine the data needed to do this efficiently, to ensure that Australia receives the greatest benefit from its antiviral drugs, vaccines and other public health interventions introduced.