Linking Estrogens, Prostatitis And Prostate Cancer
Funder
National Health and Medical Research Council
Funding Amount
$291,309.00
Summary
Prostatitis is very common and a significant health issue that affects men from their 20's. Estrogens promote inflammation and inflammation is associated with the development of cancer. If this study links estrogens, prostatitis and prostate cancer, we can provide better treatment for prostatitis, thus preventing progression to prostate cancer
Molecular Mechanisms Leading To Schizophrenia- The Role Of Estrogen And Estrogen Receptor Alpha
Funder
National Health and Medical Research Council
Funding Amount
$292,639.00
Summary
Schizophrenia (SZ) is a devastating mental illness of unknown cause thought to arise from a derailment of normal brain development where the brain fails to respond to the pubertal surge in sex steroids. This proposal aims to determine the molecular pathogenesis of SZ. The SZ susceptibility gene estrogen receptor alpha and the SZ susceptibility pathway neuregulin-ErbB4 are interrogated. This will lead to the development of novel therapeutics and preventative agents that will halt disease onset.