Improving Treatment Strategies For Chronic Alphaviral Arthritic Diseases
Funder
National Health and Medical Research Council
Funding Amount
$643,624.00
Summary
Chikungunya virus and Ross River virus cause epidemics of acute and chronic arthritic disease in humans, which is often poorly managed with current treatments. This grant seeks to understand the mechanisms that give rise to disease in order to identify improved treatment strategies. Both the persistence of viral replication in joint tissues and unnecessary inflammatory responses appear to be important factors driving chronic disease.
Engagement in early childhood education in the context of disadvantage. This research responds to enduring inequalities in children’s participation in high quality early childhood education and care (ECEC). Contemporary families face precarious labour markets and a childcare system with stringent workforce participation requirements. This project will illuminate the affordances of everyday life for families most challenged by these emergent conditions and develop understandings of how to calibr ....Engagement in early childhood education in the context of disadvantage. This research responds to enduring inequalities in children’s participation in high quality early childhood education and care (ECEC). Contemporary families face precarious labour markets and a childcare system with stringent workforce participation requirements. This project will illuminate the affordances of everyday life for families most challenged by these emergent conditions and develop understandings of how to calibrate services accordingly. Findings will support universal ECEC access through knowledge translation about contemporary disadvantage to policy and practice forums. A strong Indigenous component contributes to researcher training and knowledge about effective practice for Indigenous children and their families.Read moreRead less
Driving Change: Using Emergency Department Data To Reduce Alcohol-related Harm
Funder
National Health and Medical Research Council
Funding Amount
$1,468,026.00
Summary
The proposed project is a system change within partner emergency departments, providing them the information and tools to act on both risky alcohol consumption in individual patients and the sources of alcohol in the community which cause the harm they experience. Most importantly, the proposed public health interventions act as a tool for emergency departments to regularly raise awareness with the public and policymakers regarding the impact of alcohol on patients, clinicians and hospitals.
Young children in digital society: An Online Tool for service provision . This project aims to identify the practices enacted and shared amongst young children, their families and educators in digital society.The project is significant because in digital society families and educators face new demands ensuring technologies are used in the best interests of young children. Knowledge about practices in digital society informs adult decision-making using technologies with, by and for young children ....Young children in digital society: An Online Tool for service provision . This project aims to identify the practices enacted and shared amongst young children, their families and educators in digital society.The project is significant because in digital society families and educators face new demands ensuring technologies are used in the best interests of young children. Knowledge about practices in digital society informs adult decision-making using technologies with, by and for young children in the early years. The outcome is a new Online Tool for the Partner Organisations to share exemplar practices benefiting Australian children, their families and educators with new resources, materials and programs in areas including: digital media production, cyber-safety education, digital play and digital parenting.
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The Role And Inheritance Of Constitutional Epimutations In Early-onset Colorectal Cancer.
Funder
National Health and Medical Research Council
Funding Amount
$347,551.00
Summary
Traditionally familial cancers are thought to be caused by spelling mistakes within the genetic code of cancer prevention genes. Our group has found that chemical attachments to one gene (MLH1) stops it working, even where there is no spelling mistake, and that those chemical changes can be inherited in families with bowel cancer. We will determine how frequently this type of defect occurs in bowel cancer patients, how and why it arises, and if other cancer genes are similarly affected.
'Digital Natives': Growing up with new and old media in Australia. Developing a sophisticated digital literacy is important for both the future of children, the cultural, social and economic well-being of the nation. Digital literacy requires not only communications infrastructure but targeted investment in human skills. Investing in the development of a digitally literate Australian population has become an explicit means for promoting the future economic and social well-being of the nation. Th ....'Digital Natives': Growing up with new and old media in Australia. Developing a sophisticated digital literacy is important for both the future of children, the cultural, social and economic well-being of the nation. Digital literacy requires not only communications infrastructure but targeted investment in human skills. Investing in the development of a digitally literate Australian population has become an explicit means for promoting the future economic and social well-being of the nation. The information provided by this project has the potential to contribute significantly to giving children 'a healthy start to life' in their early years. Read moreRead less
Epimutations As Germ-line Defects In Hereditary Cancer Syndromes
Funder
National Health and Medical Research Council
Funding Amount
$385,925.00
Summary
Traditionally familial cancers were thought to be caused and inherited by spelling mistakes within the genetic code of cancer prevention genes. Our group has found that a 'chemical coat' around the MLH1 gene, causing it to be switched off, can also be inherited in some cases of bowel cancer, without any mistakes within the gene's code. We will determine if this 'coat' causes other types of cancer and if this runs in families. We also hope to find out how the coat is formed and may be reversed.
Novel water treatment processes. The objective of this project is the discovery of novel methods for the treatment and reuse of water for both industrial and household applications. Improved treatment systems with the potential for water reuse offer significant improvements to our overall water management potential. The first part of the project is designed to focus on the study of hot bubble column evaporators for solute decomposition, sterilisation and the de-watering of heavily contaminated i ....Novel water treatment processes. The objective of this project is the discovery of novel methods for the treatment and reuse of water for both industrial and household applications. Improved treatment systems with the potential for water reuse offer significant improvements to our overall water management potential. The first part of the project is designed to focus on the study of hot bubble column evaporators for solute decomposition, sterilisation and the de-watering of heavily contaminated industrial wastewater. The second part would be based on the study of a suitable depth filter medium for the treatment of partially treated household sewage water. This is designed to form part of an on-site household sewage water treatment and reuse system which is currently being developed.Read moreRead less
Observe, Reflect, Improve: a tool to enrich Children’s Learning (ORICL). This project aims to address long-standing concerns about the quality of education and care for children during their critical first two years. It will introduce a promising, future-focused digital tool, co-designed with practitioners and providers of early childhood services, to support infant-toddler educators’ planning and practice. Building on ground-breaking pilot work, we will undertake a national implementation and e ....Observe, Reflect, Improve: a tool to enrich Children’s Learning (ORICL). This project aims to address long-standing concerns about the quality of education and care for children during their critical first two years. It will introduce a promising, future-focused digital tool, co-designed with practitioners and providers of early childhood services, to support infant-toddler educators’ planning and practice. Building on ground-breaking pilot work, we will undertake a national implementation and evaluation of the Observe, Reflect and Improve Children’s Learning (ORICL) tool. Expected outcomes include: enhanced pedagogical practices; enriched learning experiences for children birth-two; effective communication with families; and improved resourcing for providers of early childhood education and care services. Read moreRead less
ARC Centre of Excellence for the Digital Child. Our vision is for Australian children to be healthy, educated and connected. This Centre will integrate child health, education, and digital and social connectedness, innovating across disciplines to meet Australia’s ongoing challenges of supporting young children growing up in a rapidly changing digital age. The Centre’s world-leading team investigates children’s digital practices through three interconnected research programs supported by a longi ....ARC Centre of Excellence for the Digital Child. Our vision is for Australian children to be healthy, educated and connected. This Centre will integrate child health, education, and digital and social connectedness, innovating across disciplines to meet Australia’s ongoing challenges of supporting young children growing up in a rapidly changing digital age. The Centre’s world-leading team investigates children’s digital practices through three interconnected research programs supported by a longitudinal family cohort study and children’s technology laboratories. The Centre will address tensions in a contested field to inform government and non-government policy, technology innovation, and develop programs and guidelines for children, families, educators and technology developers. Read moreRead less