Improving Quality Of Life In Late Stage Bipolar Disorder: RCT Of A Novel Psychological Treatment
Funder
National Health and Medical Research Council
Funding Amount
$1,083,620.00
Summary
Hundreds of thousands of Australians have bipolar disorder and receive minimal benefit from existing drug and psychological treatments. ORBIT 2.0 is a new low-intensity online treatment using mindfulness strategies to improve quality of life in this poorly served ‘late stage’ group. Pilot testing suggests ORBIT is effective. This project will refine the intervention and is expected to confirm its clinical and cost effectiveness prior to international roll-out.
Tailoring Targeted Therapy To DNA Repair-defective High-Grade Serous Ovarian Cancer
Funder
National Health and Medical Research Council
Funding Amount
$802,247.00
Summary
Ovarian cancer is a major cause of cancer death in women because current treatments are inadequate. Half of aggressive ovarian cancers have abnormalities in DNA repair and should be susceptible to new PARP inhibitor therapy, yet not all those respond. By developing a new model of studying human ovarian cancers in mice, we can discover markers to predict which ovarian cancers will respond best to these exciting new treatments.
Improved Landfill Barrier Design for Changing Climates. The proposed research project will develop advanced methods and guidelines for practising engineers for improved engineering and design of waste containment barrier systems, leading to improved protection of groundwater resources and the environment and sustainable development of the country. The project will contribute to the priority area of building an environmentally sustainable Australia with a specific focus on water as a critical re ....Improved Landfill Barrier Design for Changing Climates. The proposed research project will develop advanced methods and guidelines for practising engineers for improved engineering and design of waste containment barrier systems, leading to improved protection of groundwater resources and the environment and sustainable development of the country. The project will contribute to the priority area of building an environmentally sustainable Australia with a specific focus on water as a critical resource.Read moreRead less
Arsenite oxidation by a novel bacterium that is a candidate for arsenic bioremediation. The arsenic munching microbe NT-26 could help in the fight to clean up arsenic-contaminated mining waste and drinking water. Arsenic poses an environmental problem in countries such as Australia, USA and Canada owing primarily to mining activities. The problem in countries such as Bangladesh and West Bengal are even more serious as these people are dying of arsenic-related diseases as they rely on water conta ....Arsenite oxidation by a novel bacterium that is a candidate for arsenic bioremediation. The arsenic munching microbe NT-26 could help in the fight to clean up arsenic-contaminated mining waste and drinking water. Arsenic poses an environmental problem in countries such as Australia, USA and Canada owing primarily to mining activities. The problem in countries such as Bangladesh and West Bengal are even more serious as these people are dying of arsenic-related diseases as they rely on water containing arsenic as their primary source of drinking water. The outcomes of this research should provide the necessary information for removing arsenic from all types of waters.Read moreRead less
A fundamental study of the simultaneous gold dissolution during the alkaline oxidation of sulfide containing refractory gold ores and concentrates. The gold industry is Australia's second largest export earner and therefore is immensely important to the Australian economy. The proposed project aims to develop an environmentally acceptable process for treating gold containing sulfidic ores and concentrates that are not amenable to conventional cyanidation. This would provide an enormous benefit t ....A fundamental study of the simultaneous gold dissolution during the alkaline oxidation of sulfide containing refractory gold ores and concentrates. The gold industry is Australia's second largest export earner and therefore is immensely important to the Australian economy. The proposed project aims to develop an environmentally acceptable process for treating gold containing sulfidic ores and concentrates that are not amenable to conventional cyanidation. This would provide an enormous benefit to both the Australian gold industry and the Australian environment. A successful outcome in the research project would also lead to export earnings emanating from technology transfer and enhance Australia's reputation for high quality research and academic endeavours.Read moreRead less
Optimising gold recovery whilst minimising cyanide and copper discharges during the processing of gold ores containing copper. The presence of copper is a major problem in Australia's gold industry. We have proposed an innovative method for treating copper containing ores which eliminates discharge of copper and cyanide to the tailings dam. The copper is recovered, and the cyanide is either recycled or destroyed within the plant. Another advantage of the process is a reduction in the cyanide req ....Optimising gold recovery whilst minimising cyanide and copper discharges during the processing of gold ores containing copper. The presence of copper is a major problem in Australia's gold industry. We have proposed an innovative method for treating copper containing ores which eliminates discharge of copper and cyanide to the tailings dam. The copper is recovered, and the cyanide is either recycled or destroyed within the plant. Another advantage of the process is a reduction in the cyanide requirement, hence reducing the risk associated with cyanide transport and storage. Thus the proposed project has the potential to substantially improve the gold recovery process, particularly in an era where environmental and public concerns exist over the use of cyanide.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0989125
Funder
Australian Research Council
Funding Amount
$150,000.00
Summary
Enhanced Capacity in Ultra-Trace Level Detection and Speciation of Compounds of Environmental, Biological and Materials Science Interest. The proposed integrated facility will strongly support collaborative research in areas of high national priority. These are environmental sustainability, development of new materials and designing molecules of therapeutic value on the basis of better understanding the relevant biological processes. This support will lead to maximizing the outcomes of numerous ....Enhanced Capacity in Ultra-Trace Level Detection and Speciation of Compounds of Environmental, Biological and Materials Science Interest. The proposed integrated facility will strongly support collaborative research in areas of high national priority. These are environmental sustainability, development of new materials and designing molecules of therapeutic value on the basis of better understanding the relevant biological processes. This support will lead to maximizing the outcomes of numerous projects already funded by the Australian Research Council which require accurate and highly sensitive analysis. This will improve the cost effectiveness of research funding and will further strengthen the outstanding reputation of Australia science worldwide.Read moreRead less
Development of Leakage Resistant Well-Cements for Geo-Sequestration of Carbon Dioxide Application using Alkali Activated Slag and Geopolymer Cements. The biggest threat facing life now is climate change due to carbon dioxide (CO2) emissions. Extreme weathers are increasing in frequency and intensity, as evidenced by recent bushfires, and it is predicted to get worse unless carbon mitigation strategies are quickly implemented. Geo-sequestration is the technology of capturing and storing of the CO ....Development of Leakage Resistant Well-Cements for Geo-Sequestration of Carbon Dioxide Application using Alkali Activated Slag and Geopolymer Cements. The biggest threat facing life now is climate change due to carbon dioxide (CO2) emissions. Extreme weathers are increasing in frequency and intensity, as evidenced by recent bushfires, and it is predicted to get worse unless carbon mitigation strategies are quickly implemented. Geo-sequestration is the technology of capturing and storing of the CO2 deep below ground for long time (>1000 years). It offers the best hope for large reductions of CO2 emissions. However, CO2-brine stored under pressure is acidic and has the risk of leaking in the long term by dissolving the cement used to seal the pipe wells. This project will develop alternative novel cements which are acid resistant and will not allow CO2 to leak through the sealed wells.Read moreRead less
Application of nano-sized zero valent iron particles to agrochemicals degradation through Fenton's reagent oxidation. Zero-valent iron (ZVI) has been successfully used for the degradation of a wide range of contaminant organics in groundwaters in recent years. The rates of degradation however are relatively slow and render the process unsuitable for situations where there are limits on the time available for reaction. An innovative approach is to couple the dissolution of ZVI with hydrogen perox ....Application of nano-sized zero valent iron particles to agrochemicals degradation through Fenton's reagent oxidation. Zero-valent iron (ZVI) has been successfully used for the degradation of a wide range of contaminant organics in groundwaters in recent years. The rates of degradation however are relatively slow and render the process unsuitable for situations where there are limits on the time available for reaction. An innovative approach is to couple the dissolution of ZVI with hydrogen peroxide addition thereby generating hydroxyl radicals as a result of Fenton's reagent reactions. The efficacy of using this innovative ZVI/H2O2 process to degrade herbicides and pesticides of concern to Australian agriculture is investigated at laboratory and field scale in this project.Read moreRead less
Identifying novel, health-related predictors of recidivism: Informing evidence-based throughcare. Throughcare is a policy priority for correctional authorities in Australia, however the evidence base to inform policy is limited. Using innovative modelling techniques and unique data from a large, representative cohort of ex-prisoners in Queensland, this study will: identify novel, health-related predictors of recidivism in the first two years after release from adult custody; examine the extent t ....Identifying novel, health-related predictors of recidivism: Informing evidence-based throughcare. Throughcare is a policy priority for correctional authorities in Australia, however the evidence base to inform policy is limited. Using innovative modelling techniques and unique data from a large, representative cohort of ex-prisoners in Queensland, this study will: identify novel, health-related predictors of recidivism in the first two years after release from adult custody; examine the extent to which risk and protective factors for recidivism vary over time and according to individual characteristics; and, provide evidence-based recommendations to improve throughcare interventions and reduce recidivism.Read moreRead less