Dissecting The Pseudoexfoliation Syndrome With Complementary Genetic, Proteomic And Biophysical Strategies
Funder
National Health and Medical Research Council
Funding Amount
$490,352.00
Summary
Pseudoexfoliation syndrome (PEX) is an eye condition in which flaky material deposits in the eye, greatly increasing the risk of cataract and glaucoma which can lead to blindness. PEX is also associated with heart disease, strokes and aneurysms. Cataract surgery in PEX patients has a higher rate of complications. In this project we will determine the nature of PEX material and why it forms. This knowlege will facilitate better diagnosis and treatment of PEX preventing associated blindness.
A Genome-wide Association Study In 2000 Glaucoma Cases With Matched Controls Using Equimoloar DNA Pools
Funder
National Health and Medical Research Council
Funding Amount
$610,267.00
Summary
Glaucoma is a common cause of loss of vision worldwide but we are unable to predict which people are at high risk of blindness. We aim to discover the genetic risk factors for glaucoma. We will use cutting edge genetic technology to assess the whole genome in thousands of patients with glaucoma. We hope to identify important new glaucoma genes, which could lead to the development of diagnostic tests and treatments which will provide the most cost-efficient ways to prevent glaucoma blindness.
Aboriginal and non-Aboriginal sex-offenders in Australia: Assessing risk for practice and policy. A key priority of Australian governments is to improve community safety through reducing the risk of sex offenders re-offending after release from prison. This project will assess the validity of tools used to predict the risk of sexual offender recidivism and identify alternate risk assessment tools for Indigenous and non-Indigenous sex offenders.
Capital Offending: Income, Work and Crime in Australia’s Convict Era. At least 60 per cent of Australia’s current prison population has been in prison before. By contrast a mere 18 per cent of transported convicts were re-incarcerated following release. This project aims to use information on the bank accounts maintained for convicts while under sentence to measure the relationship between capital formation and post-sentence marriage, migration and reconviction rates. It will look in particular ....Capital Offending: Income, Work and Crime in Australia’s Convict Era. At least 60 per cent of Australia’s current prison population has been in prison before. By contrast a mere 18 per cent of transported convicts were re-incarcerated following release. This project aims to use information on the bank accounts maintained for convicts while under sentence to measure the relationship between capital formation and post-sentence marriage, migration and reconviction rates. It will look in particular at the extent to which skills, employment opportunities and asset accumulation enabled former transported convicts to go straight. It will also result in improved archival search engines enabling access for members of the public to internationally recognised record groups hitherto held by different institutions.Read moreRead less
Rebuilding fiscal federalism in Australia: reforming the financial relationship between the Commonwealth and the States. The finances of the Australian States in the modern day face serious structural challenges. The aim of this project is to analyse and develop appropriate alternatives for reform of fiscal federalism in Australia, which would allow the States to gain access to income tax revenue as a secure source of funding in the future.
Enabling social innovation for local climate adaptability. Climate variability and change is likely to be felt most acutely at the local scale in Australia. This is where inter/national and State policies are translated into practices to prepare for, and adapt to, anticipated impacts of heatwaves, bushfires and floods. This project will investigate tensions and potentialities between risk-based assessments by local governance agencies and innovations by local groups and Non-Government Organisati ....Enabling social innovation for local climate adaptability. Climate variability and change is likely to be felt most acutely at the local scale in Australia. This is where inter/national and State policies are translated into practices to prepare for, and adapt to, anticipated impacts of heatwaves, bushfires and floods. This project will investigate tensions and potentialities between risk-based assessments by local governance agencies and innovations by local groups and Non-Government Organisations. The research will utilise an innovative mixed-methods approach to investigate and to analyse the strategies and experiments of adaptation practices. It aims to develop new ways of identifying and implementing practical, local, adaptive responses that are contextually relevant, socially innovative and capacity building.Read moreRead less
Global Citizen Deliberation: Analysing a Deliberative Documentary. The project will enact and film the world’s first truly global citizens’ deliberation, a global citizens’ assembly (GCA) on genome editing, and proceed to analyse the impact of the ‘deliberative documentary’ film on public understanding of complex, fast-evolving science and technology. It will investigate the cross-cultural capacity of citizens to deliberate complex value-laden issues, and so ascertain prospects for an informed g ....Global Citizen Deliberation: Analysing a Deliberative Documentary. The project will enact and film the world’s first truly global citizens’ deliberation, a global citizens’ assembly (GCA) on genome editing, and proceed to analyse the impact of the ‘deliberative documentary’ film on public understanding of complex, fast-evolving science and technology. It will investigate the cross-cultural capacity of citizens to deliberate complex value-laden issues, and so ascertain prospects for an informed global public response to challenges posed by genome editing. Research will test the effects of the deliberative documentary on viewers, examining benefits of communicating complex issues via the work of the GCA. Other benefits include improving public trust in governance and advancing the Australian film industry.
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Industrial Transformation Training Centres - Grant ID: IC220100003
Funder
Australian Research Council
Funding Amount
$4,930,205.00
Summary
ARC Training Centre for Biofilm Research and Innovation . The ARC Training Centre for Biofilm Research and Innovation aims to transform biofouling management strategies for maritime platforms by building on local and international expertise to mentor and train the next generation of interdisciplinary scientists and engineers. Anticipating evolving regulatory stringency, this project expects to establish a dynamic environment for industry partners, students and scientists to collaborate and devel ....ARC Training Centre for Biofilm Research and Innovation . The ARC Training Centre for Biofilm Research and Innovation aims to transform biofouling management strategies for maritime platforms by building on local and international expertise to mentor and train the next generation of interdisciplinary scientists and engineers. Anticipating evolving regulatory stringency, this project expects to establish a dynamic environment for industry partners, students and scientists to collaborate and develop biofilm management strategies. Expected outcomes include new and enhanced collaborations that advance and translate knowledge to better manage biofouling. The significant benefits will include a generation of industry-focused researchers critical for growing Australia’s Defence industry.Read moreRead less
Community Engagement for Productive Ageing: Models to support rural healthy ageing through the maintenance of community involvement and contribution. Governments at all levels are concerned about the looming social and economic challenges flowing from an ageing population. At present, ageing services are largely focussed on caring for the frail dependent aged. Yet, ultimately, the key to meeting the ageing challenge will lie in how successful we are in supporting our healthy independent aged to ....Community Engagement for Productive Ageing: Models to support rural healthy ageing through the maintenance of community involvement and contribution. Governments at all levels are concerned about the looming social and economic challenges flowing from an ageing population. At present, ageing services are largely focussed on caring for the frail dependent aged. Yet, ultimately, the key to meeting the ageing challenge will lie in how successful we are in supporting our healthy independent aged to stay contributing and productive members of their community. By developing evidence-based interventions that focus on preventing social disengagement before it occurs, the project provides a cost effective approach to ensuring that Australia's rapidly growing aged cohort remain social assets and do not become social burdens.Read moreRead less
The age of personalised medicine: regulatory challenges for Australia. Australia is entering an age of personalised medicine where therapies and tests will be based on individual genetic profiles. This project aims to ensure that there is a best practice regulatory and governance environment for facilitating responsible research and clinical service delivery through a process of evidence-based regulatory reform.