Premature Mortality Post Fracture:A NSW Linked Data Study
Funder
National Health and Medical Research Council
Funding Amount
$391,012.00
Summary
Osteoporotic fractures are associated with increased morbidity and mortality. Anti-osteoporosis medications reduce re-fracture and possibly morality, yet osteoporosis is poorly treated. This study will link information from >260,000 people (45&Up study) with hospital admissions, medications and deaths to create the largest, detailed dataset of its kind. We will be able to determine cause of any fracture-associated mortality and the effect of medication to improve osteoporosis management.
Conjugate natural convection boundary layers. Conjugate natural convection systems occur when a conducting vertical wall separates fluids at different temperatures (that is at a window separating the interior of a room from the outside or when a container of fluid is placed in a refrigerator). This project will provide accurate predictions of such flows together with scaling relations.
Reducing the energy consumed by lighting with gaze-dependent illumination. Lighting consumes approximately 18% of electricity, but only a fraction of the light emitted into buildings actually supports occupants’ vision – the rest is wasted. This research aims to reduce the energy consumed by lighting by developing strategies for illuminating only the portions of architectural environments that are visible to occupants, thereby reducing unnecessary light. The impacts of gaze-dependent lighting on ....Reducing the energy consumed by lighting with gaze-dependent illumination. Lighting consumes approximately 18% of electricity, but only a fraction of the light emitted into buildings actually supports occupants’ vision – the rest is wasted. This research aims to reduce the energy consumed by lighting by developing strategies for illuminating only the portions of architectural environments that are visible to occupants, thereby reducing unnecessary light. The impacts of gaze-dependent lighting on energy consumption and the visual environment will be characterized and design guidelines will be generated to facilitate the development of innovative lighting systems that consume less energy by producing less light, without negatively impacting the visual experiences of building occupants.Read moreRead less
Enhancing passive cooling using flexible baffles. The project aims to develop a novel passive strategy using fluid-structure-thermal interactions to enhance passive cooling by natural convection and improve the energy efficiency of engineering systems. Comparing to the existing strategies, the new strategy does not require driving fan or pump and is quiet, reliable, self-adaptive and economical. The Multiphysics embodied in the proposal is at the leading edge of the field. Expected outcomes incl ....Enhancing passive cooling using flexible baffles. The project aims to develop a novel passive strategy using fluid-structure-thermal interactions to enhance passive cooling by natural convection and improve the energy efficiency of engineering systems. Comparing to the existing strategies, the new strategy does not require driving fan or pump and is quiet, reliable, self-adaptive and economical. The Multiphysics embodied in the proposal is at the leading edge of the field. Expected outcomes include advanced understanding of the complex Multiphysics and design rules for enhancing passive cooling by natural convection using flexible baffles. The research is expected to bring direct economic benefit to relevant industry and significant environmental and social benefit to the general public.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE180100203
Funder
Australian Research Council
Funding Amount
$956,700.00
Summary
Novel diagnostics capabilities in reacting, particle-laden flows. This project aims to establish innovative capabilities for advanced diagnostics techniques to be applied in reacting, particle-laden flows over a range of pressures. The complementary measurements are expected to provide an unprecedented understanding of the dynamics of liquid fragments and solid particles in flames. The resulting data, and improved knowledge, will set the framework for more effective predictive methods that assis ....Novel diagnostics capabilities in reacting, particle-laden flows. This project aims to establish innovative capabilities for advanced diagnostics techniques to be applied in reacting, particle-laden flows over a range of pressures. The complementary measurements are expected to provide an unprecedented understanding of the dynamics of liquid fragments and solid particles in flames. The resulting data, and improved knowledge, will set the framework for more effective predictive methods that assist in the design of cleaner and efficient processes that benefit a range of applications, from engine design to the generation of new fuels, and the flame synthesis of novel materials.Read moreRead less
Perinatal Stress Leads To Neurosteroid Deficits And Adverse Behavioural Outcomes
Funder
National Health and Medical Research Council
Funding Amount
$1,198,042.00
Summary
This grant will examine the effect of psychosocial stress experienced after birth on the production and regulation of steroid hormones in the brain of newborn animals. The work will investigate how stress changes the levels these brain steroids and sensitivity to them and if these effects are remain into adulthood. The studies will then determine if these changes lead to adolescent behaviour disorders. The effectiveness of steroid therapies in treating these disorders will also be determined.
Large Scale Natural Convection Boundary Layers with Non-Boussinesq Effects. This proposal aims to understand and predict heat transfer by turbulent natural convection in two scenarios, firstly at very large environmental scales, such as occur on melting Antarctic ice sheets, and secondly convection involving very large temperature differences such as occur in solar thermal power plants and industrial processes. These natural convection flow regimes are incredibly difficult to investigate directl ....Large Scale Natural Convection Boundary Layers with Non-Boussinesq Effects. This proposal aims to understand and predict heat transfer by turbulent natural convection in two scenarios, firstly at very large environmental scales, such as occur on melting Antarctic ice sheets, and secondly convection involving very large temperature differences such as occur in solar thermal power plants and industrial processes. These natural convection flow regimes are incredibly difficult to investigate directly but by focusing on the fundamental dynamics of the turbulent flows using large scale numerical simulations and innovative experiments, the project is expected to develop better analytical and computational models which will underpin improvements in
global ocean models and improve energy efficiency.Read moreRead less
Fundamental flaws in the design and reporting of research outcomes can undermine evidence-based medicine, impede patient-centred care, cause harm to patients, and result in a waste of research dollars. Our 3-year multinational project engages with patients, caregivers, clinicians, researchers and policy makers, to establish core outcomes in haemodialysis. This will ensure that patient-centred outcomes are consistently measured and reported in haemodialysis trials and other forms of research.
Is Placental Aging The Key To Understanding, Predicting And Preventing Stillbirth?
Funder
National Health and Medical Research Council
Funding Amount
$473,861.00
Summary
Stillbirth occurs in 35 times as many pregnancies as sudden infant death but the causes are unknown. This project will help to develop tests that can predict the risk of stillbirth so that the obstetrician can deliver the baby before it dies. The investigators hypothesise that stillbirth is due to aging of the placenta and that markers of the aging placenta can be detected in the mother’s blood. The project brings together experts in the placenta, aging and obstetric care of high risk pregnancy.
Entrainment and Mixing in Turbulent Negatively Buoyant Jets and Fountains. The project intends to develop tools to accurate predict fountain flows. Volcanic eruptions, building ventilation and brine discharge from desalination plants are all examples of turbulent fountains and negatively buoyant jets. The project aims to conduct an investigation into the turbulent structure of fountains and negatively buoyant jets using numerical simulation and laboratory experiments, and to assess the accuracy ....Entrainment and Mixing in Turbulent Negatively Buoyant Jets and Fountains. The project intends to develop tools to accurate predict fountain flows. Volcanic eruptions, building ventilation and brine discharge from desalination plants are all examples of turbulent fountains and negatively buoyant jets. The project aims to conduct an investigation into the turbulent structure of fountains and negatively buoyant jets using numerical simulation and laboratory experiments, and to assess the accuracy of the commonly used integral models and test the effect of the use of more accurate entrainment relations. This may have a range of applications – enabling better prediction of environmental impacts, reduction of the adverse effects of the discharge of pollutants, and reduction in energy consumption in building ventilation and other industrial applications.Read moreRead less