From The Synchrotron To The Clinic: Translation Of A Novel Functional Lung Imaging Technology
Funder
National Health and Medical Research Council
Funding Amount
$891,834.00
Summary
Our team has recently developed a synchrotron technology with a startling capacity for dynamic functional imaging that can act as a sensitive regional indicator of lung disease. We will demonstrate that this technology can be translated from the synchrotron to the lab and eventually the clinic. We will provide proof of this concept by the application of this technology to emphysema, asthma, lung cancer, cystic fibrosis lung disease and neonatal resuscitation.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE240100073
Funder
Australian Research Council
Funding Amount
$1,150,000.00
Summary
A femtosecond beamline for time-resolved momentum microscopy. This project aims to obtain a femtosecond high-harmonic generation beamline that will be integrated with a photoemission electron microscope to create Australia’s first time-resolved momentum microscope. This project expects to use ultrafast spectromicroscopy to observe the changes to the excited electron motion within materials after they absorb light. Expected outcomes of this project include improving our understanding of light-dri ....A femtosecond beamline for time-resolved momentum microscopy. This project aims to obtain a femtosecond high-harmonic generation beamline that will be integrated with a photoemission electron microscope to create Australia’s first time-resolved momentum microscope. This project expects to use ultrafast spectromicroscopy to observe the changes to the excited electron motion within materials after they absorb light. Expected outcomes of this project include improving our understanding of light-driven physical and chemical processes that occur in materials and optoelectronic devices. This should provide significant benefits through the development of new cost effective and efficient materials for energy harvesting, sensors and photocatalysts.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100229
Funder
Australian Research Council
Funding Amount
$250,000.00
Summary
A prototype Scanning Helium Atom Microscope (SHeM) for soft materials. The scanning helium atom microscope (SHeM) has been a tantalising prospect since the birth of quantum physics. The SHeM would have unparalleled resolution and would be completely non-damaging; potentially revolutionising the imaging of soft delicate materials. This project will develop the first SHeM instrument in Australia to study soft matter.
Fibre sensors with subwavelength features in the Terahertz radiation (T-ray) regime. With this program, Australia will benefit from expertise in photonics that will develop new chemical biosensors based on optical fibre technology. The novelty is that the fibres will be used to guide Terahertz radiation (T-ray) frequencies that will be able to detect very small samples of material or fluid. This is a fundamental step towards a system that will impact on applications in the medical, pharmaceutica ....Fibre sensors with subwavelength features in the Terahertz radiation (T-ray) regime. With this program, Australia will benefit from expertise in photonics that will develop new chemical biosensors based on optical fibre technology. The novelty is that the fibres will be used to guide Terahertz radiation (T-ray) frequencies that will be able to detect very small samples of material or fluid. This is a fundamental step towards a system that will impact on applications in the medical, pharmaceutical, forensic, and security industries. Ultimately, Australia will benefit from a new cutting-edge technology and a new diagnostic biosensing technique.Read moreRead less
Terahertz optoelectronics based on spintronics materials. Spintronic devices have many advantages which include non-volatility, permitting data retention in non-powered conditions, increased integration densities, high data processing speeds, low electrical energy demands, and a fabrication process compatible with those currently used in semiconductor microelectronics. The low energy consumption of spintronic devices also leads to economic and environmental benefits. Spintronic devices will help ....Terahertz optoelectronics based on spintronics materials. Spintronic devices have many advantages which include non-volatility, permitting data retention in non-powered conditions, increased integration densities, high data processing speeds, low electrical energy demands, and a fabrication process compatible with those currently used in semiconductor microelectronics. The low energy consumption of spintronic devices also leads to economic and environmental benefits. Spintronic devices will help to meet the sensing and storage demands of information technology in the decades to come. The project will enhance the international competitiveness and export power of Australian industry in the areas of information technology, quantum computing, magnetic recording and optoelectronics.Read moreRead less
Innovative Grid-Connected, Small-Scale Wind Turbine Generators Offering Low Cost and Wide Operating Speed Range. Growing concerns about sustainability issues with fossil fuels have resulted in strong interest in wind power worldwide. Grid-connected inverters are an efficient way of utilising small wind turbines on domestic, farming or small commercial properties which have access to the power grid. Existing small-scale, grid-connected wind turbines are expensive and have a limited operating wind ....Innovative Grid-Connected, Small-Scale Wind Turbine Generators Offering Low Cost and Wide Operating Speed Range. Growing concerns about sustainability issues with fossil fuels have resulted in strong interest in wind power worldwide. Grid-connected inverters are an efficient way of utilising small wind turbines on domestic, farming or small commercial properties which have access to the power grid. Existing small-scale, grid-connected wind turbines are expensive and have a limited operating wind speed range. We are investigating new designs for low-cost wind turbine generators which can produce power over a wide range of wind speeds. The project should result in a greater application of small-scale wind generators in Australia and will lead to reductions in fossil fuel usage and greenhouse gas emissions.Read moreRead less
Epilepsy: Molecular Basis And Mechanisms In The Era Of Functional Genomics
Funder
National Health and Medical Research Council
Funding Amount
$12,062,533.00
Summary
The team comprises of neurologists with a special interest in epilepsy (both adult and child) molecular geneticists, physiologists and brain imaging specialists. The team leads the world in the discovery of the genetic causes of epilepsy and epilepsy associated with intellectual disability. The team will continue to identify the genes underlying epilepsy, and study how genetic variations result in the development of seizures and will continue to develop advanced imaging techniques for these stud ....The team comprises of neurologists with a special interest in epilepsy (both adult and child) molecular geneticists, physiologists and brain imaging specialists. The team leads the world in the discovery of the genetic causes of epilepsy and epilepsy associated with intellectual disability. The team will continue to identify the genes underlying epilepsy, and study how genetic variations result in the development of seizures and will continue to develop advanced imaging techniques for these studies. This will include extensive laboratory studies, including the development of mice with the exact mutations that we find in the human condition. Stateof-the-art imaging techniques with magnetic resonance and positron emission tomography are used in human subjects to further understand the effects of the mutations on the structure and function of the brain. This will allow deep understanding of how seizures develop and may lead to new diagnostic methods and treatments. The laboratory and clinical aspects of the research are tightly integrated in this internationally leading collaborative program.Read moreRead less
Novel RF Controlled Electromechanical Microvalve. The significance of the proposed microvalve is its potential use in exciting biomedical applications such as in drug delivery and fertility control. For human body implantation, it must be batteryless, wireless and be made of a biofriendly-polymer. We propose to meet all three criteria, based on novel use of surface acoustic waves (SAWs) as the actuation mechanism in a polymer material. Energy for actuation will be supplied by a radio frequency ( ....Novel RF Controlled Electromechanical Microvalve. The significance of the proposed microvalve is its potential use in exciting biomedical applications such as in drug delivery and fertility control. For human body implantation, it must be batteryless, wireless and be made of a biofriendly-polymer. We propose to meet all three criteria, based on novel use of surface acoustic waves (SAWs) as the actuation mechanism in a polymer material. Energy for actuation will be supplied by a radio frequency (RF) signal. We propose to model, design and demonstrate the device in laboratory conditions. This will enable development of application specific designs in future programs, such as ARC linkage.Read moreRead less