Single Shot X-ray Tomography For Real-Time Functional X-ray Imaging
Funder
National Health and Medical Research Council
Funding Amount
$322,641.00
Summary
Computed Tomography (CT) scanners produce three-dimensional images of vital organs that cannot be obtained by conventional two-dimensional (single projection) x-ray radiographs. However, the radiation exposure is hundreds of times higher than conventional radiography. We will develop the world’s first CT scanner that uses no more radiation than a single conventional x-ray image that will provide four-dimensional reconstructions of a patient’s moving internal organs.
Discovery Early Career Researcher Award - Grant ID: DE230100192
Funder
Australian Research Council
Funding Amount
$458,318.00
Summary
Quantum sensing of magnetism in two dimensions. This project aims to use innovative quantum sensing technologies to investigate the novel emerging field of two-dimensional magnetism; imaging both static and dynamic forms of 2D magnetism. This project expects to generate new knowledge about magnetic van der Waals materials and their potential application to ultra-thin electronic and spintronic devices. Expected outcomes of this project are a deeper understanding of the formation and modulation of ....Quantum sensing of magnetism in two dimensions. This project aims to use innovative quantum sensing technologies to investigate the novel emerging field of two-dimensional magnetism; imaging both static and dynamic forms of 2D magnetism. This project expects to generate new knowledge about magnetic van der Waals materials and their potential application to ultra-thin electronic and spintronic devices. Expected outcomes of this project are a deeper understanding of the formation and modulation of magnetic order in 2D, new fabrication methods for deliberate domain wall formation, production of near-zero energy gap spin-waves, and new encapsulation methods for ultra-stable 2D materials. This should provide significant benefits towards fundamental physics and future device engineering. Read moreRead less
Developing Interpretable Machine Learning Models For Clinical Imaging And Single-cell Genomics
Funder
National Health and Medical Research Council
Funding Amount
$1,312,250.00
Summary
Machine learning methods will be vital to make best use of the deluge of data generated by high-throughput technologies in biomedical science. To get the most out of these models, however, we need to be able to unpack the 'black box'. I will use curated clinical and public research data to benchmark and develop interpretable deep learning models and software tools. These models will be used for breast cancer screening programs and for analysis of complex, large-scale single-cell genomics data.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE240100092
Funder
Australian Research Council
Funding Amount
$1,100,000.00
Summary
Quantum microscopy facility for ultrasensitive nanoscale magnetic imaging. Investigations of 2D and van der Waals materials, biological samples, energy materials, and quantum devices on the nano- and microscale are revolutionising medicine, communications, information technology, energy production and storage by virtue of new phenomena. The new quantum microscopy facility will enable state-of-the-art capabilities in mapping chemical, magnetic, optical, electronic, and spectral properties, provid ....Quantum microscopy facility for ultrasensitive nanoscale magnetic imaging. Investigations of 2D and van der Waals materials, biological samples, energy materials, and quantum devices on the nano- and microscale are revolutionising medicine, communications, information technology, energy production and storage by virtue of new phenomena. The new quantum microscopy facility will enable state-of-the-art capabilities in mapping chemical, magnetic, optical, electronic, and spectral properties, providing cutting-edge tools that will enable breakthroughs in both existing and future multi-disciplinary projects in photonics, quantum devices, nanomaterials, nanoelectronics, biotechnology, and energy technology as key drivers of the new economy in Australia.Read moreRead less
Unlocking the potential of magnetic 2D materials with quantum microscopy. This project aims to create a universal, high-throughput platform to characterise magnetic 2D materials, by exploiting recently developed quantum diamond microscopy. It will enable the measurement of hitherto inaccessible magnetic properties of individual 2D microsheets, the imaging of device-relevant phenomena such as domain wall dynamics and skyrmionics, and the systematic screening of newly synthesised materials. Antici ....Unlocking the potential of magnetic 2D materials with quantum microscopy. This project aims to create a universal, high-throughput platform to characterise magnetic 2D materials, by exploiting recently developed quantum diamond microscopy. It will enable the measurement of hitherto inaccessible magnetic properties of individual 2D microsheets, the imaging of device-relevant phenomena such as domain wall dynamics and skyrmionics, and the systematic screening of newly synthesised materials. Anticipated outcomes include crucial new insights into 2D magnetism and the discovery of magnetic 2D materials compatible with real-world conditions. This should accelerate the development of future energy-efficient and flexible electronics and memory technologies, where magnetic 2D materials are expected to play a key role.
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From The Synchrotron To The Clinic: Translation Of A Novel Functional Lung Imaging Technology
Funder
National Health and Medical Research Council
Funding Amount
$891,834.00
Summary
Our team has recently developed a synchrotron technology with a startling capacity for dynamic functional imaging that can act as a sensitive regional indicator of lung disease. We will demonstrate that this technology can be translated from the synchrotron to the lab and eventually the clinic. We will provide proof of this concept by the application of this technology to emphysema, asthma, lung cancer, cystic fibrosis lung disease and neonatal resuscitation.
Imaging Neutrophil And Endothelial Function In Acute Glomerulonephritis
Funder
National Health and Medical Research Council
Funding Amount
$545,517.00
Summary
The glomerulus is a group of small blood vessels which form the filtering component of the kidney. In many diseases, it can be the target of an inappropriate inflammatory response during which white blood cells accumulate in the glomerular blood vessels and cause damage. In this project, we will visualise the blood vessel lining of the glomerulus in order to understand how white blood cells damage this region and cause leakage of protein leak into the urine.
Efficacy Of A 3-month Aerobic Exercise Regime For Restoring 'brain Health' In Heavy Cannabis Users
Funder
National Health and Medical Research Council
Funding Amount
$1,209,221.00
Summary
Over a ten-year period, we, and others have documented the brain and psychological harms associated with regular cannabis use. We have now shown that these harms are not permanent, but can be restored. However, the recovery process takes a long time. This study will build on our extensive work to date and, for the first time, investigate whether a specific form of exercise will cause accelerated and beneficial changes in i) the brain and ii) the daily lives of heavy cannabis users.
Aspirin For The Prevention Of Cognitive Decline In The Elderly: A Neuro-Vascular Imaging Study (ENVIS-ion) From ASPREE
Funder
National Health and Medical Research Council
Funding Amount
$1,341,232.00
Summary
The ENVIS-ion trial will examine whether Aspirin is effective in delaying the onset of worsening of thinking and memory abilities in healthy older adults. Magnetic resonance imaging (MRI) of brain structure will detect markers of early worsening of thinking and memory abilities. Blood vessels in the back of the eye (retina) share many features with vessels in the brain. We will compare whether aspirin lessens changes over time of features shown with brain MRI and retinal photography.