Haemodynamic investigation of flow diverter stents for the treatment of intracranial aneurysms. This project will explore the engineering of a flow diverter, an endovascular device for the treatment of brain aneurysms. The project will determine the optimal design of new types of flow diverters, which in turn could improve the effectiveness of treatments, thus reducing the associated costs of cerebral haemorrhage and stroke.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE130100128
Funder
Australian Research Council
Funding Amount
$670,000.00
Summary
Helium and neon ion microscope for sub nanometer imaging and fabrication. The project's proposed instrument would add a new desperately needed capability to Australia's high resolution microscopy centre and nano fabrication facility and enable a wide range of users to image, measure, build and design complex nanostructures at the atomic level and upwards.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE110100159
Funder
Australian Research Council
Funding Amount
$360,000.00
Summary
National facility for biased target deposition of alloyed nanolayers. This facility will enhance Australia's strengths and capabilities in fabricating structures, with applications in multiple research fields including opto-magneto-electronics, next generation lithium ion batteries and energy nanogenerators. It will enhance Australia's research profile as a leader in nanotechnology.
Technology platform for noninvasive measurement of intracranial pressure. The project aims to investigate a technology platform for noninvasive measurement of fluid pressure in the brain to improve assessment of brain function. Engineering approaches will aim to characterise the relationships between arterial and intracranial pressure from experimental data, computational models and signal processing of noninvasive blood pressure in the aorta, pressure in the eye and blood flow in brain and reti ....Technology platform for noninvasive measurement of intracranial pressure. The project aims to investigate a technology platform for noninvasive measurement of fluid pressure in the brain to improve assessment of brain function. Engineering approaches will aim to characterise the relationships between arterial and intracranial pressure from experimental data, computational models and signal processing of noninvasive blood pressure in the aorta, pressure in the eye and blood flow in brain and retinal vessels. Findings are expected to produce novel engineering advances in development of techniques and devices for intracranial pressure measurement, a procedure currently limited to high-risk invasive methods.Read moreRead less
Advancing hybrid imaging with magnetic resonance imaging and positron emission tomography (MRI-PET). This project aims to increase the utility, accessibility, cost-effectiveness and accuracy of magnetic resonance imaging and positron emission tomography (MRI-PET) hybrid imaging technology for brain tumour imaging. This project will develop new contrast agents, better ways of measuring their uptake including a new high sensitivity MRI-PET head coil and methods for predicting tumour progression us ....Advancing hybrid imaging with magnetic resonance imaging and positron emission tomography (MRI-PET). This project aims to increase the utility, accessibility, cost-effectiveness and accuracy of magnetic resonance imaging and positron emission tomography (MRI-PET) hybrid imaging technology for brain tumour imaging. This project will develop new contrast agents, better ways of measuring their uptake including a new high sensitivity MRI-PET head coil and methods for predicting tumour progression using imaging information.Read moreRead less
Biological determinants of the safety and stability of neuroprosthetic stimulation electrodes. Performance of cochlear implants and the quality of sound perceived by patients is strongly related to electrode impedance. Electrode impedance fluctuates relative to the implant electrical activity, but the mechanisms which cause this are not clear. This project aims to investigate the role of protein adsorption in electrode performance, including impedance and material dissolution. To enable these in ....Biological determinants of the safety and stability of neuroprosthetic stimulation electrodes. Performance of cochlear implants and the quality of sound perceived by patients is strongly related to electrode impedance. Electrode impedance fluctuates relative to the implant electrical activity, but the mechanisms which cause this are not clear. This project aims to investigate the role of protein adsorption in electrode performance, including impedance and material dissolution. To enable these investigations a new biomimetic analogue of the perilymph (cochlea fluid) is intended to be developed. Additionally, the project aims to investigate two strategies to minimise impedance changes: small pulse electrode cleaning and antifouling coatings. Understanding and control of factors influencing electrode stability aim to facilitate next-generation implant designs.Read moreRead less
Improved effectiveness of cochlear implants through new simultaneous stimulation techniques. Cochlear implants have brought the gift of hearing to 250,000 people worldwide and are an excellent example of Australian innovation. This project will examine an improved "high fidelity" stimulation strategy with the objective of defining a safe stimulus range for clinical use and providing a commercial advantage for Cochlear Ltd.
Laser emission at the limit of glass transparency using nanocrystal doping . We will create a new composite glass providing strong fluorescence which fully exploits the high transmission of glass in the mid-infrared. When combined with emerging rare earth ion transitions and precise excitation processes, this project will help solve an important problem in optics; that the overall efficiency and power produced from deep mid-infrared light sources is not sufficient for all industries. The primary ....Laser emission at the limit of glass transparency using nanocrystal doping . We will create a new composite glass providing strong fluorescence which fully exploits the high transmission of glass in the mid-infrared. When combined with emerging rare earth ion transitions and precise excitation processes, this project will help solve an important problem in optics; that the overall efficiency and power produced from deep mid-infrared light sources is not sufficient for all industries. The primary outcome will be a series of robust fibre-based gain modules suitable for high power and very short optical pulses in the mid-infrared. These light sources will beneficially impact medicine, defence, sensing and manufacturing providing excellent opportunities for increasing Australian productivity and global competitiveness. Read moreRead less
Through a glass brightly: opening up the mid-infrared using dysprosium ions. By exploiting the dysprosium ion in a unique and practical way, the project will create high power mid-infrared light with unprecedented optical efficiency. The project will make use of the unusually wide fluorescence spectrum of the dysprosium ion to produce stable and bandwidth-limited ultra-fast light pulses in the mid-infrared. The proposed light sources will have application in mid-infrared nonlinear optics and wil ....Through a glass brightly: opening up the mid-infrared using dysprosium ions. By exploiting the dysprosium ion in a unique and practical way, the project will create high power mid-infrared light with unprecedented optical efficiency. The project will make use of the unusually wide fluorescence spectrum of the dysprosium ion to produce stable and bandwidth-limited ultra-fast light pulses in the mid-infrared. The proposed light sources will have application in mid-infrared nonlinear optics and will benefit medicine, defence, fundamental physics and manufacturing providing excellent opportunities for Australian research, industry and collaboration.Read moreRead less
Circuit-based monitoring and characterisation of high performance semiconductor processes. As a frontier technology, this project extends Australia's leadership in wireless communications. Potentially this project provides the key enabling method for integrated circuits to take full advantage of future generations of semiconductor technology. National Research Priorities safeguarding Australia and promoting and maintaining good health will also be impacted through more capable circuits for def ....Circuit-based monitoring and characterisation of high performance semiconductor processes. As a frontier technology, this project extends Australia's leadership in wireless communications. Potentially this project provides the key enabling method for integrated circuits to take full advantage of future generations of semiconductor technology. National Research Priorities safeguarding Australia and promoting and maintaining good health will also be impacted through more capable circuits for defence electronics and anti-terrorism, medical remote sensing and networking. The innovations here will make Sapphicon, Australia's only commercial integrated circuit manufacturer, more competitive and indirectly benefit National ICT Australia (NICTA), Commonwealth Scientific and Industrial Research Organisation (CSIRO), Defence Science and Technology Organisation (DSTO), the National Broadband Network and a host of other high-performance electronics concerns.Read moreRead less