Investigation Of A New Electronic Portal Imaging Device For Radiation Therapy Dose Delivery Verification
Funder
National Health and Medical Research Council
Funding Amount
$408,101.00
Summary
In external beam radiotherapy highly complex radiation fields are used to deliver high doses of radiation to the tumour while sparing normal tissues. Inaccurate treatment could result in poor patient outcome or damage to normal tissues. We aim to investigate a novel imaging device to measure the dose accuracy of these fields. This work has the potential to make a significant and fundamental difference to existing verification techniques for radiotherapy treatments to ensure patient outcomes.
Improving Outcomes Of Radiotherapy Treatments Through In-vivo Dosimetric Verification
Funder
National Health and Medical Research Council
Funding Amount
$379,855.00
Summary
Radiotherapy remains an important non-surgical treatment for over 50 % of cancer patients. This project aims to develop methods that will enable the optimisation of the patients' treatment as it progresses by non-invasively measuring the radiation dose delivered each day. This will increase the likelihood of curing the patient as well as reducing the side effects experienced due to the treatment. This will improve the patients' quality of life post-treatment.
The Use Of Electronic Portal Imaging Devices For The Dosimetric Verification Of Complex Radiotherapy Treatments
Funder
National Health and Medical Research Council
Funding Amount
$260,949.00
Summary
The prognosis for someone diagnosed with cancer is much better than commonly believed. If detected early, malignant tumours are generally well localised. During these early stages of tumour growth high doses of radiation therapy can with a high probability, eradicate a cancer but come with the cost of causing unacceptable damage to normal tissue. A specific goal of improving the technology of radiation therapy is to reduce the probability of damage to normal tissue. Achieving this goal may allow ....The prognosis for someone diagnosed with cancer is much better than commonly believed. If detected early, malignant tumours are generally well localised. During these early stages of tumour growth high doses of radiation therapy can with a high probability, eradicate a cancer but come with the cost of causing unacceptable damage to normal tissue. A specific goal of improving the technology of radiation therapy is to reduce the probability of damage to normal tissue. Achieving this goal may allow delivery of higher doses with an associated increase in the chance of controlling the tumour. One of the challenges in radiation therapy is that tumours do not come in shapes that are easy to treat. Tumours extend into cavities and push aside healthy organs growing into complex 3D shapes. The careful shaping of the radiation beams to deliver dose distributions that match the 3D shape of the target is known as 3D conformal radiotherapy (3DCRT). Intensity Modulated Radiotherapy (IMRT) is an advanced form of 3DCRT that allows the delivered dose to be closely tailored to the shape of complex tumour volumes while sparing neighbouring healthy tissues. One of the consequences of increasing the conformality of radiation therapy is an increased sensitivity to errors in the preparation and execution of the treatment. If the maximum gain in the treatment outcome using 3DCRT and IMRT techniques is to be achieved then it is crucial that the correct volume is treated to the correct dose on each day of the treatment. This requires new improved methods and techniques for verifying the daily delivery of the treatment. In this project we aim to develop the use of online digital imaging devices for measuring the delivered dose during treatment. This will increase the confidence with which these new conformal radiotherapy techniques can be delivered allowing their true potential for improving patient treatment outcomes to be realised.Read moreRead less
Microelectronic Applications of Improved Silicon Light Emission. While semiconductor silicon chips have been the workhorse of the microelectronics revolution, more complex semiconductor materials have driven the communications revolution. Australian developments during 2001 have largely dispelled the myth that silicon is fundamentally a poor emitter of light. This project aims to build on this work by developing silicon light emitters suitable for integration into high density integrated circu ....Microelectronic Applications of Improved Silicon Light Emission. While semiconductor silicon chips have been the workhorse of the microelectronics revolution, more complex semiconductor materials have driven the communications revolution. Australian developments during 2001 have largely dispelled the myth that silicon is fundamentally a poor emitter of light. This project aims to build on this work by developing silicon light emitters suitable for integration into high density integrated circuits, adding a new dimension to the capabilities of these circuits, driving microelectronics and the information age to the next stage of development.Read moreRead less
Centre for Advanced Silicon Photovoltaics and Photonics. Silicon photovoltaics (Si PV) is a priority area within the Photon Science and Technology category. Multiple studies have identified PV solar electricity as the most promising option for a sustainable energy future, with Australia already at the forefront internationally in Si PV. The applicants recently have shown that insights from PV also may provide the key to the successful development of active Si photonic devices for integration i ....Centre for Advanced Silicon Photovoltaics and Photonics. Silicon photovoltaics (Si PV) is a priority area within the Photon Science and Technology category. Multiple studies have identified PV solar electricity as the most promising option for a sustainable energy future, with Australia already at the forefront internationally in Si PV. The applicants recently have shown that insights from PV also may provide the key to the successful development of active Si photonic devices for integration into microelectronics. The Centre's aims and expected outcomes are to strengthen this technological lead in Si PV while pioneering the development of active Si photonic devices for microelectronic integration, with economic, cultural and social benefits.Read moreRead less
A Single Digital Handheld Imaging Device For Use In Both Ophthalmology And Dentistry
Funder
National Health and Medical Research Council
Funding Amount
$431,221.00
Summary
Our aim is to produce and validate a single digital imaging device which can be used in ophthalmology (both for retinal and anterior segment imaging) and dentistry. This device will be low-cost, easy-to-operate and portable. Our planned development of the novel screening tool should help in bringing high quality, lower cost health care to those without easy access to it, firstly to residents of rural areas in Australia and then in developing countries in our region. This can be achieved by more ....Our aim is to produce and validate a single digital imaging device which can be used in ophthalmology (both for retinal and anterior segment imaging) and dentistry. This device will be low-cost, easy-to-operate and portable. Our planned development of the novel screening tool should help in bringing high quality, lower cost health care to those without easy access to it, firstly to residents of rural areas in Australia and then in developing countries in our region. This can be achieved by more efficient screening methods and redirecting resources to target those with treatable eye disease only. The detection process can be progressively transferred to less expensive health workers while ophthalmologist input can be redirected to monitoring the screening results and performing surgery. The dentists travel infrequently to rural and remote WA. If the dentist can pre plan their treatment then it will be more efficient and possible to treat more people at each visit to remote and rural WA. With the help of the proposed imaging device for dentistry, the nurses and other allied personnel should be able to send the digital images in advance to dentist over Internet and therefore help dentist pre-plan their treatment. As a result, improved dental care for rural, remote and underserved communities will occur.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0238960
Funder
Australian Research Council
Funding Amount
$940,000.00
Summary
High Performance Semiconductor Micromachining Facility. The purpose of this project is to make available to the Australian semiconductor research community a facility to undertake specialist deposition and etching tasks needed for fabrication of next generation solar cells, microelectronics, optronics, and micro-electromechanical systems. The facility will have the flexibility to allow independent control of major process parameters, allowing development of new fabrication technologies which wi ....High Performance Semiconductor Micromachining Facility. The purpose of this project is to make available to the Australian semiconductor research community a facility to undertake specialist deposition and etching tasks needed for fabrication of next generation solar cells, microelectronics, optronics, and micro-electromechanical systems. The facility will have the flexibility to allow independent control of major process parameters, allowing development of new fabrication technologies which will be generic to a wide range of semiconductor materials. In particular, the facility will be unique in its ability to perform processes at low temperatures, and under conditions that allow optimisation of the deposition and etching processes, without compromising the performance of delicate devices or exceeding the maximum process temperature limitations found in many mainstream semiconductor materials technologies.Read moreRead less