Characterising Lung Growth And Development In Health And Disease
Funder
National Health and Medical Research Council
Funding Amount
$451,716.00
Summary
A/Prof Graham Hall is senior researcher at the Telethon Institute for Child Health Research in Perth, Western Australia and is internationally recognised for his research in the area of respiratory physiology in infants and young children. His research focuses on understanding the impact of respiratory diseases, such as asthma and cystic fibrosis, as well as pre-term birth and air pollution on lung function not only in early life but as the lung grows and develops.
Understanding The Biology Of Pregnancy To Prevent Morbidity And Mortality
Funder
National Health and Medical Research Council
Funding Amount
$422,746.00
Summary
Progress in the care of the unborn baby, and thus optimisation of life-long health, will only come with a greater understanding of the fundamental processes that underlie pregnancy. My research is aimed at saving babies lives and reducing the long-term burdens (health, emotional and economic) of major perinatal conditions. I am uniquely placed to carry out this research, using the research tools I have developed to deliver real outcomes that will change clinical practice
Protecting Newborn Brains Via Innovative Monitoring Technology
Funder
National Health and Medical Research Council
Funding Amount
$394,460.00
Summary
This project aims to develop innovative brain monitoring technology which could help minimise brain damage in newborn babies with brain injuries, thereby delivering a healthier start to life. Such novel technology may automatically analyse babies’ brain activity and deliver instant detection of critical abnormalities, which could enable more effective treatment of brain injuries. Babies with reduced oxygen or blood supply to the brain and premature babies could benefit from such innovations.
Transcriptional Regulation Of Hematopoietic Commitment
Funder
National Health and Medical Research Council
Funding Amount
$289,985.00
Summary
Blood cell formation is a tightly regulated process and provides an important model for our understanding of blood homeostasis. Perturbations result in a number of disorders such as leukaemia. The application of stem cells to many diseases is being pursued; yet, to be successful knowledge of normal cellular behavior is crucial. I aim to improve our understanding of these processes and help to provide the framework for future studies aimed at more directly manipulating blood cell functions.
Understanding Typical And Atypical Development Of The Infant Brain
Funder
National Health and Medical Research Council
Funding Amount
$428,065.00
Summary
This project will apply advanced magnetic resonance imaging (MRI) techniques to understand how brain abnormalities in preterm infants relate to their functional impairments. It aims to: develop new software to easily and accurately measure infant brain structures and tissues; understand the neurobiological basis for adverse outcomes, enabling diagnosis of high risk preterm infants; and identify MRI biomarkers to assess interventions designed to give Australian babies a healthier start to life.
Reducing Perinatal Lung, Heart And Brain Injury In Preterm Infants – From Bench To The Clinic.
Funder
National Health and Medical Research Council
Funding Amount
$463,652.00
Summary
Many infants are exposed to an adverse environment whilst developing in the womb, and are therefore at increased risk of lung, heart and brain injury, with life-long consequences. This research is focused on improving the entry into the world of vulnerable infants, thus reducing the risk and severity of brain injury.