Detection and viability of waterborne pathogens using a gut-on-chip. This project aims to resolve a significant problem for water utilities. Microbial pathogens Cryptosporidium, norovirus and adenovirus are the main public health concern for drinking water in developed nations. Water monitoring is limited by the lack of fast, reliable detection methods and viability assays for these pathogens. This project will use a novel gut-on-a-chip to develop for the first time rapid infectivity assays for ....Detection and viability of waterborne pathogens using a gut-on-chip. This project aims to resolve a significant problem for water utilities. Microbial pathogens Cryptosporidium, norovirus and adenovirus are the main public health concern for drinking water in developed nations. Water monitoring is limited by the lack of fast, reliable detection methods and viability assays for these pathogens. This project will use a novel gut-on-a-chip to develop for the first time rapid infectivity assays for Cryptosporidium, norovirus and adenovirus. Significant benefits include improved diagnostics and water disinfection assays, improved water treatment and reduced costs with global impact.Read moreRead less
Lizard social networks and the spread of parasites. Australian ecosystems are continually threatened by new epidemics of diseases and parasites, some local, others from overseas. Examples include the facial tumours of Tasmanian devils and the fungus that threatens many native frog species. To manage these epidemics effectively, we must understand how they spread through animal populations. This project will help to protect our fauna from invasive diseases. It contributes to sustaining the biodiv ....Lizard social networks and the spread of parasites. Australian ecosystems are continually threatened by new epidemics of diseases and parasites, some local, others from overseas. Examples include the facial tumours of Tasmanian devils and the fungus that threatens many native frog species. To manage these epidemics effectively, we must understand how they spread through animal populations. This project will help to protect our fauna from invasive diseases. It contributes to sustaining the biodiversity of the country. With better knowledge of how diseases of wildlife spread, we can develop more effective control of those diseases thereby protecting wildlife species, animal populations and, ultimately, Australian ecosystems.Read moreRead less
Running Hot: Increasing the Availability of World-Class Precision Timing . Precision clocks are a key enabler for many important technologies including navigation, radar, distributed computing and communications. Unfortunately, the very best clocks are currently bulky and very expensive. This project will take Australia’s multi-award winning sapphire clock technology and transform it so that its unmatched performance is available from a unit with an order of magnitude smaller size, power consum ....Running Hot: Increasing the Availability of World-Class Precision Timing . Precision clocks are a key enabler for many important technologies including navigation, radar, distributed computing and communications. Unfortunately, the very best clocks are currently bulky and very expensive. This project will take Australia’s multi-award winning sapphire clock technology and transform it so that its unmatched performance is available from a unit with an order of magnitude smaller size, power consumption and cost. This transformation will be driven on the back of a patented revolutionary step that allows operation of the sapphire clock at higher cryogenic temperatures. The new clock will have a wider range of applications delivering more computational power, higher bandwidth transmissions and better radar. Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE130100133
Funder
Australian Research Council
Funding Amount
$400,000.00
Summary
National Facility for Physical Blast Simulation (NFPBS). Recent terrorist attacks employing large quantities of high explosives have prompted the international demand for experimental investigation of civil infrastructure response to shock wave loadings. The National Facility for Physical Blast Simulation (NFPBS) is one of only a few in the world that are suitable for conducting experimental research via a physically generated blast approach.
Phylogeography, evolution and taxonomy of humanity's greatest pest, Rattus rattus: Epidemiological, archaeological and conservation implications. This project will characterise a major threat to Australian biosecurity and health, and identify the range of likely disease risks associated with introductions of different 'strains' of black rat. It will provide critical data for management efforts around the world, especially for strategic partners in neighbouring Southeast Asian nations, as well as ....Phylogeography, evolution and taxonomy of humanity's greatest pest, Rattus rattus: Epidemiological, archaeological and conservation implications. This project will characterise a major threat to Australian biosecurity and health, and identify the range of likely disease risks associated with introductions of different 'strains' of black rat. It will provide critical data for management efforts around the world, especially for strategic partners in neighbouring Southeast Asian nations, as well as for conservation efforts within Australia. The data will also provide novel means to track the timing and routes of human prehistoric movements throughout the area. It will establish strategic research collaborations between researchers in zoological, medical, epidemiological, genetics, and conservation fields in a unique multi-disciplinary study.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE150100001
Funder
Australian Research Council
Funding Amount
$410,000.00
Summary
Collaborative advanced spectroscopy facility for materials and devices. Collaborative advanced spectroscopy facility for materials and devices: This project aims to enable advancements in electronics, photonics, biomedicine, and sensing through a collaborative, open access facility for advanced optical and chemical spectroscopy of thin films, materials, and devices. The intended capabilities include high-speed, precise and state-of-the-art spectroscopy tools which enable in situ characterisation ....Collaborative advanced spectroscopy facility for materials and devices. Collaborative advanced spectroscopy facility for materials and devices: This project aims to enable advancements in electronics, photonics, biomedicine, and sensing through a collaborative, open access facility for advanced optical and chemical spectroscopy of thin films, materials, and devices. The intended capabilities include high-speed, precise and state-of-the-art spectroscopy tools which enable in situ characterisation at sub-micron scales and cryogenic temperatures, under bio-simulated environments, down to single pixel resolution, with parallel imaging and spectroscopy, and of fluids and biomaterials. The instrumentation will include cryogenic sub-micron photoluminescence and micro-Raman spectroscopy, single pixel optical and dark field spectroscopy, continuous wave terahertz time-domain spectroscopy, wide wavelength microscopic spectroscopy, and temperature-jump kinetics spectroscopy. It is expected that these complementary instruments will accelerate research in materials and devices for plasmonics, nanoelectronics, biomedicine, biochemistry, security, and forensic science.Read moreRead less
Functional characterisation of poly-histidine triad proteins. This project aims to understand the role and function of a novel family of surface proteins produced by Streptococci. These so-called polyhistidine triad proteins are known to contribute to capacity to cause disease in animals and humans, but we need to know how they work, as they may be excellent targets for novel drugs or vaccines.
Novel perspectives on the function of AB5 toxin B subunits in pathogenic bacterial. AB5 toxins are produced by bacteria that cause important diseases in humans and livestock. This project tests the hypothesis that the components of the toxins responsible for binding to host cells and tissues also directly contribute to cellular damage, thereby providing a better understanding of how AB5 toxin-producing bacteria cause disease.
Space-based space surveillance with robust computer vision algorithms. Space-based space surveillance with robust computer vision algorithms. This project aims to develop computer vision algorithms to detect man-made objects in space. These algorithms function on nanosatellite platforms, enabling space-based space surveillance. This technology is expected to provide always-on monitoring of the Earth's orbit to enhance existing defence infrastructure and protect vital space assets, including comm ....Space-based space surveillance with robust computer vision algorithms. Space-based space surveillance with robust computer vision algorithms. This project aims to develop computer vision algorithms to detect man-made objects in space. These algorithms function on nanosatellite platforms, enabling space-based space surveillance. This technology is expected to provide always-on monitoring of the Earth's orbit to enhance existing defence infrastructure and protect vital space assets, including communications and navigational satellites, in Earth’s orbit from collisions and covert sabotage. Increased space use by government and civilian agencies opens up opportunities for the space industry. This project is expected to develop Australia’s space surveillance capabilities, protect space assets and capture a growing market.Read moreRead less
Quantum Nanostructure Positioning for Breakthrough Quantum Photonics. The integration of quantum nanostructures in optical devices has been proposed to improve the efficiencies of existing optical devices and create new classes of quantum photonics. Limiting progress is that many nanostructures are made through bottom-up processes with inherently randomly distributions, making integration into devices problematic. Lithographic nanostructure fabrication is rarely an option as it leads to diminish ....Quantum Nanostructure Positioning for Breakthrough Quantum Photonics. The integration of quantum nanostructures in optical devices has been proposed to improve the efficiencies of existing optical devices and create new classes of quantum photonics. Limiting progress is that many nanostructures are made through bottom-up processes with inherently randomly distributions, making integration into devices problematic. Lithographic nanostructure fabrication is rarely an option as it leads to diminishes performance. Here, we propose a new and unique nanostructure positioning technique incorporated directly into the growth process. It interfaces bottom-up technologies with device fabrication, facilitating incorporation of nanostructures in photonic devices, and may be transferrable to a variety of other systems.Read moreRead less